Gene Information

Name : tkt_1 (HMPREF9243_0107)
Accession : YP_004320519.1
Strain : Aerococcus urinae ACS-120-V-Col10a
Genome accession: NC_015278
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 108972 - 110969 bp
Length : 1998 bp
Strand : +
Note : identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232

DNA sequence :
ATGTTTAATCAAACAGATGAACTCGCTGTGAATGCAGTGCGTATGTTAAGTATTGATATGATTAACAAGGCTAATTCCGG
TCACCCAGGCCTACCTATGGGTGTAGCACCTATGGCCTATGCATTATGGGCAGAACACATGGTGCAAAACCCAAGTGATC
CCCACTGGACCAACCGGGACCGCTTTGTCTTATCAGCGGGGCATGGGTCTGCCTTACTCTATAGCTTATTACACCTATCT
GGTTACCAAGTGACCATGGATGATATTAAACAATTCCGTCAATTAAATTCCAAGACTCCTGGTCACCCCGAAGTCCACTT
TACCGAAGGGGTCGAAGCGACCACTGGTCCATTAGGCCAAGGTTTTGCTAATGCAGTAGGGATGGCTATGGCAGAAGCCC
ATGACGCTGCTATCTATAACCAAGGTGACTATAAGATCGTTGACCATTACACCTATGCCCTCTGTGGGGACGGGGACTTG
ATGGAAGGTATTTCCCATGAAGCGGCTTCCCTAGCTGGCCACCTCCAATTAGGCAAATTGATTGTCTTCTATGACTCCAA
CGACATTTCTCTAGACGGCCCAACTGACAAGGCCTTCACCGAAGACAATAAGGGCCGGTTCGAAGCTTACGGCTGGCAAC
ATATTCTAGTGGAAGATGGCCGTGACTTAGAAGCCATTTCCAAAGCCGTGGAAGCAGCCAAAGCTGAAACCAATAAACCA
ACCCTCATCCAAGTCAAAACCGTGATCGGTTACGGTTCTGAAAATGAAGGCACTTCCGCAACACACGGGAACCCAATTGG
TGAAGAAGACCGGGCTCACGCTGCCCAAGTTTACGGTTGGAACCATGAAGCCTTTGATATTCCTCAAGAAGTTTACAATC
GCTTCCAAGAACGGGTCGCTGACCGTGGAGCTCAGGCGCAAGCAGACTGGCAAGAAGAATTCAAGGCCTATGAAGCCGAC
TATGCGGACTTAGCTGCCCAATATCAACGCGCCTATGCCGGTGAATTACCCGCTGACTGGGCGGACTGCCTGCCTAGCTA
TGACGTTAACGATGAGGCTATGGCTTCGCGGAAAACCAGCCAAAAAGCCATCCAAGCCATTGCTCAAACTCTCCCTGAAT
TCTGGGGCGGGTCTGCGGACTTGAAGTCCTCCAACAATACTTACATTGACGCCGATAGTGACTTTGAAGCTGGAAATTAT
GCGGGTCGTAACATTTGGTATGGTGTCCGTGAGTTTGGCATGGGTGCTGCCATGAACGGGATTCGTTTACACGGCGGGTC
GATTCCTTATGCCGGAACCTTCTTTGTCTTCTCGGACTATCTCCGGGCAGCTATGCGGGTAGCGGCATTATCCCACTTAC
CTTCAACCTTTGTCTTTACCCATGACTCCATTGCCGTTGGAGAAGATGGACCAACCCATGAACCGATTGAACAGTTAGCG
GCTTTCAGAGCCATGCCAAATATCAACACCATCCGCCCAGCTGACGGTAACGAAGTCTCTGCGGCTTGGAAGCTCGCTAT
CGAGGCTAAAGATACGCCAACAGTTCTGGCCCTGTCCCGGCAAAACCTCCCTGTGCTCAAAGGCACCGCTGATAAAGCTA
TGGAAGGGGTCGCTCGAGGCGCCTATGTCTTATCCGATGCCCAAGGGGATACCCCAGACGGTATCTTGATTGCCACCGGT
TCAGAAGTGAACTTAGCCCTGGAAGCTCAGGCCGAACTGGCTAAGGACGGTATCGACGTCCGTGTGGTTTCCATGCCTTG
TCAAGAGCTCTTCGACCAAGAAGACCAAGCTTATAAGGAAAGTGTTCTCCCAAGTGAAGTCAAAAACCGGATGGCCATCG
AAATGGCTGCTACATTTGGTTGGGAACGCTATGTCGGCGACCAAGGCGTCGTGCTTGGCTTAGACCGCTATGGCCAATCA
GGTAAGGGCGGCCAAGTCATGGAAGCTTTAGGCTTTAACCTGGACAATGTCGTAAAAACCTACAAAAACGCCTTTTAA

Protein sequence :
MFNQTDELAVNAVRMLSIDMINKANSGHPGLPMGVAPMAYALWAEHMVQNPSDPHWTNRDRFVLSAGHGSALLYSLLHLS
GYQVTMDDIKQFRQLNSKTPGHPEVHFTEGVEATTGPLGQGFANAVGMAMAEAHDAAIYNQGDYKIVDHYTYALCGDGDL
MEGISHEAASLAGHLQLGKLIVFYDSNDISLDGPTDKAFTEDNKGRFEAYGWQHILVEDGRDLEAISKAVEAAKAETNKP
TLIQVKTVIGYGSENEGTSATHGNPIGEEDRAHAAQVYGWNHEAFDIPQEVYNRFQERVADRGAQAQADWQEEFKAYEAD
YADLAAQYQRAYAGELPADWADCLPSYDVNDEAMASRKTSQKAIQAIAQTLPEFWGGSADLKSSNNTYIDADSDFEAGNY
AGRNIWYGVREFGMGAAMNGIRLHGGSIPYAGTFFVFSDYLRAAMRVAALSHLPSTFVFTHDSIAVGEDGPTHEPIEQLA
AFRAMPNINTIRPADGNEVSAAWKLAIEAKDTPTVLALSRQNLPVLKGTADKAMEGVARGAYVLSDAQGDTPDGILIATG
SEVNLALEAQAELAKDGIDVRVVSMPCQELFDQEDQAYKESVLPSEVKNRMAIEMAATFGWERYVGDQGVVLGLDRYGQS
GKGGQVMEALGFNLDNVVKTYKNAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-155 52
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-152 50