Gene Information

Name : Sph21_0227 (Sph21_0227)
Accession : YP_004315479.1
Strain : Sphingobacterium sp. 21
Genome accession: NC_015277
Putative virulence/resistance : Resistance
Product : ATPase P
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 249682 - 252168 bp
Length : 2487 bp
Strand : +
Note : TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: gfo:GFO_1200 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; PFAM: ATPase

DNA sequence :
ATGAAAAAAACAAAAATAAACTTAGACATACTCCTTCCCGAAATCCCCGATGAACGGGATCGTTGCGTTGAGCGTTTAAT
AAAATTGCTGGAAGGCAGAAATGGGATTGAAAAGGTACATCTCAAACCTCAAAATAAGCAAAGTAAAGCTCAATTATGTT
TCCACTATGACCCGGATGTTATCTCCATCGATAGAATACAAAGCTTAGCTAAAAAAGCGGGAGCCACATTTACCGAAAAA
TTCGGACATTTATTGATACACACAGATGGTGTTCGACATGTAAGACATGCACGGCTCATTGAAAGCAGATTGAAGCGAAT
CAAAGGTTTTACGACGGTATCCGTTTCGGGAACGGGAGTAATGTATATCGAATTCGACCATCACAAAATCAATCAAAAGG
AGGTTGAACGCTCAATAACAGCTATGGGAATTAAAATAATTTCTAATGAGCAAGCACAATTTATCGGACAGAAAAGTGAC
GGGATAGATAAACACTTGGACAAAAAGAATGAGGAGAGTAAGTCAAAGGAGCATGATCATGTCCATGGGGGTATATTCGG
CAAAAACGCTGAACTCGTTTTTAGCATTATTTCAGGGATATTATTAGGGATAGGCTTTGGTTTATCCTTTTTAGAAGGTC
TCGCTCCATGGGTTTCCCTTTGTTTCCTTTTCGGAGCTTATTTTTTCGGAGCCTACTATGTTACTAAAGAAGCCTATGAG
GCTATTTCTAAAGGAGAATTTGAAATAGATTTTTTAATGTTAGTGGCCGCCGCCGGAGCTGGGGCACTTGGACAGTGGAC
AGAAGGTGCTCTTTTATTATTTCTATTCAGTTTAGGACATGCACTCGAACACTTTGCGTTAGAAAAGGCGCGTAAATCAA
TAGCTGCACTCACCGATCTGGCACCAAAAACGGCCTTTAGAAAACATGCCGATAAAATTGAAGAAGTTCCCATCGAACAA
CTTAATATCGGCGACATTATCGTTATTCGTCCCAATACTAAAATTGCTGCAGATGGTATTGTAGTTAAAGGAACCAGCGG
GGTCAACCAGGCGCCAATTACCGGGGAAAGTATTCCCGTTGATAAGCTGGCATTTGAGAAAGAAGAGATAGATGTAAATA
AAGCTGCTACACTTGACGCAAAGTATAAAGTATTCTCGGGTTCAATTAACGGAAACGGTACATTGGAAGTGAAGGTAAGT
CGGGAAGCCAATGATTCAACAATTTCCCGGATGATTAAAATGGTTAATGAAGCGCAAACACAAAAGTCGCCCACGCAGCA
ATTTACAGATCGTTTTGAAAAACTTTTTGTCCCTGCTGTCCTGATTTTAGTGTTTTTACTGTGTTTTGCGTTTCTTGTGA
CCGACGAAACGTTTAGTGCCAGTTTTTACAGAGCGATGTCCGTGTTGGTAGCTGCCAGTCCGTGCGCCCTTGCAATATCT
ACACCCAGTGCAGTACTCAGCGGCGTTGCGCGAGCGGCAAAAGGTGGTGTTCTTATAAAAGGAGGAAAACCGCTAGAAGA
CTTGGGAACATTAACTGCTTTAGCTTTCGACAAGACAGGGACATTAACTGAAGGTAAGCCAAAACTTACGGCGGTTTTTC
CTTCTAAAGATATCGATGAAGAAACCCTGCTCAAGATTACTATAGCAGTAGAAGCGCTAAGCGACCATCCATTGGCAAAA
GCCATTGTACGGGACGGGATGAAAAGGCTCAATGATACAAACATCCCTTCTGCGGAGAGTCTTGAAGCGGTGCTCGGTAA
AGGAGTAAAAGCGAAGTTAGAAGGAGATACAATATACATTGGCAACCTTGCCCTATTTGAAACATTAGATACAAAAAAAC
CGTCGGACACCTTTGTAAAAAAAGTACAGGAACTGGAAGGTCAGGGTAATACTACCATGATAATACGAAGGAATGAAGAC
TACATAGGCATGATTGCTGTTATGGATACACCCCGCCCGGAAGCAAGGGAGGCCTTGTCCAGTCTGGAAGCTGTTGGCAT
CCGCCGTATGGTCATGTTAACCGGTGATAATCAAAAGGTAGCTGATGCTATAGCGGGTGAGATTGGCCTGTCTGACGCGT
GGGGAGGCCTGCTTCCGGAACAGAAGGTTGATGCAATAAAAAAGCTTAGGCAGCAGGAAAAGAATGTAGCGATGGTGGGT
GACGGCGTTAATGATGCACCTGCCATGGCTAATAGCACCGTTGGTATCGCAATGGGAGCTGCGGGGTCGGATGTTGCTCT
TGAGACGGCCGATATTGCTTTAATGGGAGACAATCTGAATTTGCTCCCTTTTGCAATTGGGCTTAGCCGTAAAGCAAAAG
GTATCATTAAACAAAATTTATGGATCAGCCTCGGTGTTGTCACTGTGTTAATTCCATTAACTATTCTCGGGATAGCTTCC
ATCGGCCCAGCCGTAGTAGCACATGAAGGATCAACCTTGGTTGTGGTATTTAACGCGCTGAGGCTATTGGCATACAAAAA
CGAATAA

Protein sequence :
MKKTKINLDILLPEIPDERDRCVERLIKLLEGRNGIEKVHLKPQNKQSKAQLCFHYDPDVISIDRIQSLAKKAGATFTEK
FGHLLIHTDGVRHVRHARLIESRLKRIKGFTTVSVSGTGVMYIEFDHHKINQKEVERSITAMGIKIISNEQAQFIGQKSD
GIDKHLDKKNEESKSKEHDHVHGGIFGKNAELVFSIISGILLGIGFGLSFLEGLAPWVSLCFLFGAYFFGAYYVTKEAYE
AISKGEFEIDFLMLVAAAGAGALGQWTEGALLLFLFSLGHALEHFALEKARKSIAALTDLAPKTAFRKHADKIEEVPIEQ
LNIGDIIVIRPNTKIAADGIVVKGTSGVNQAPITGESIPVDKLAFEKEEIDVNKAATLDAKYKVFSGSINGNGTLEVKVS
REANDSTISRMIKMVNEAQTQKSPTQQFTDRFEKLFVPAVLILVFLLCFAFLVTDETFSASFYRAMSVLVAASPCALAIS
TPSAVLSGVARAAKGGVLIKGGKPLEDLGTLTALAFDKTGTLTEGKPKLTAVFPSKDIDEETLLKITIAVEALSDHPLAK
AIVRDGMKRLNDTNIPSAESLEAVLGKGVKAKLEGDTIYIGNLALFETLDTKKPSDTFVKKVQELEGQGNTTMIIRRNED
YIGMIAVMDTPRPEAREALSSLEAVGIRRMVMLTGDNQKVADAIAGEIGLSDAWGGLLPEQKVDAIKKLRQQEKNVAMVG
DGVNDAPAMANSTVGIAMGAAGSDVALETADIALMGDNLNLLPFAIGLSRKAKGIIKQNLWISLGVVTVLIPLTILGIAS
IGPAVVAHEGSTLVVVFNALRLLAYKNE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 8e-103 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 6e-103 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 6e-103 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sph21_0227 YP_004315479.1 ATPase P BAC0124 Protein 3e-180 53
Sph21_0227 YP_004315479.1 ATPase P BAC0092 Protein 1e-89 41