Gene Information

Name : Marme_0124 (Marme_0124)
Accession : YP_004311264.1
Strain : Marinomonas mediterranea MMB-1
Genome accession: NC_015276
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 136677 - 138395 bp
Length : 1719 bp
Strand : +
Note : PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; TIGRFAM: Urease, subunit alpha; HAMAP: Urease, subunit alpha; KEGG: mmw:Mmwyl1_0956 urease subunit alpha

DNA sequence :
ATGAGTACATCCAAAAAAACGATGGATCGTGCGAGTTATGCTCAAATGTTTGGCCCGACGACGGGCGATAAAGTGCGTTT
AGGGGACACGGATCTTTGGATACAGGTCGAAAAAGACTTTACGACCTATGGCGATGAGGTGAAGTTCGGTGGCGGTAAAG
TAATCCGTGATGGAATGGGGCAAAGCCAATTGACCAATGATGTCGCCGTCGACCTTGTGATTACCAATGCGCTGGTGATG
GATCATTGGGGCATCGTCAAAGGGGATGTCGGCGTCAAAGACGGACGTATTTTTAAAGTCGGCAAAGCGGGCAACCCAGA
TGTACAGGACAACGTCGATATTGTCGTTGGTCCGGGTACTGAAGTCATTGCAGGGGAAGGCTCGATATTAACCGCAGGCG
GCATCGATGCTCACATCCACTTTATTTGTCCGCAACAAATTGAAGAAGCGCTGACCTCCGGTGTAACAACCATGATCGGA
GGGGGAACCGGACCTGCGACAGGAACCAATGCCACGACCTGTACTCCGGGGCCTTGGTATATTGGGAAAATGATGCAAGC
CACCGACAGCATGCCAATGAACTTAGGCTTTCTCGGAAAGGGCAATGCGAGTTTGCCTGACGCGTTGGAAGAACAGTTAG
AAGCGGGGGCGTGTGGGCTCAAATTGCATGAGGATTGGGGTACAACACCTGCTTCGATTGATTGTTGCCTGTCTGTCGCA
GAAAAGTACGATGTACAAGTGGCGATTCATACCGATACGCTTAATGAGTCGGGCTTTGTGGACAGCACTTTAGGTGCGTT
CAAAGACCGTGTTATTCATACCTATCACACGGAAGGTGCAGGCGGTGGTCATGCGCCGGATATCATTCGTGCAGCAGGTC
AGCCAAATGTGTTGCCGTCTTCAACCAACCCTACGCGTCCATATACTCACAATACCGTTGATGAACACCTTGATATGTTG
ATGGTGTGCCACCACTTGGACAGCAACATTCCAGAAGATGTTGCGTTTGCCGATTCTCGTATTCGTAAGGAAACCATAGC
GGCAGAAGATGTGTTTCATGATCGTGGTGCGTTCTCGATGATCTCTTCTGACTCTCAGGCAATGGGCCGAGTGGGAGAAG
TGGTTACTCGTACATGGCAAACCGCGCATAAGATGAAGCAACAGTTCGGTCTGCTACCGGAAGATCAAGAACTGGGTGCA
GATAACTTTCGTGCTAAGCGTTATATTGCAAAATATACAATCAACCCTGCAATTGCGCATGGCATGAGCCATGAAGTGGG
TTCCATTGAACCGGGTAAATTGGCCGATTTGGTGTTGTGGAAGCCTGCCTTTTTTGCGGTTAAACCGTCGATGATCATCA
AAGGCGGAATGATCGCAAGTGCGCCGATGGGCGACCCAAATGCGTCTATCCCAACCCCACAACCGGTTCATTATCGTCCG
ATGTTTGGTTCGTTTGGTAAGGCCAGTGCGGCAACGTCGGTGACCTTTGTGTCCGATGCAGCTTTAAAAAATGGTATTAA
AGACCGCCTTGGTTTAGATCGTTCACTGGTGGCGTGTAAAAACACGCGTACCGTCAGCAAGAAAGACATGGTTCACAATG
ATTGGATGCCTGACATTATGGTCGACCCACAAACCTATGAGGTGCGCGCAGATGGTGAATTGCTAACGTGTGAACCAGCT
AAAGAACTGCCTTTGGCGCAGTTGTATAACCTTTTTTAA

Protein sequence :
MSTSKKTMDRASYAQMFGPTTGDKVRLGDTDLWIQVEKDFTTYGDEVKFGGGKVIRDGMGQSQLTNDVAVDLVITNALVM
DHWGIVKGDVGVKDGRIFKVGKAGNPDVQDNVDIVVGPGTEVIAGEGSILTAGGIDAHIHFICPQQIEEALTSGVTTMIG
GGTGPATGTNATTCTPGPWYIGKMMQATDSMPMNLGFLGKGNASLPDALEEQLEAGACGLKLHEDWGTTPASIDCCLSVA
EKYDVQVAIHTDTLNESGFVDSTLGAFKDRVIHTYHTEGAGGGHAPDIIRAAGQPNVLPSSTNPTRPYTHNTVDEHLDML
MVCHHLDSNIPEDVAFADSRIRKETIAAEDVFHDRGAFSMISSDSQAMGRVGEVVTRTWQTAHKMKQQFGLLPEDQELGA
DNFRAKRYIAKYTINPAIAHGMSHEVGSIEPGKLADLVLWKPAFFAVKPSMIIKGGMIASAPMGDPNASIPTPQPVHYRP
MFGSFGKASAATSVTFVSDAALKNGIKDRLGLDRSLVACKNTRTVSKKDMVHNDWMPDIMVDPQTYEVRADGELLTCEPA
KELPLAQLYNLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-177 70
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-177 70
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-159 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-159 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-159 64
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-159 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Marme_0124 YP_004311264.1 urease subunit alpha VFG0270 Protein 8e-154 63