Gene Information

Name : Marme_1076 (Marme_1076)
Accession : YP_004312187.1
Strain : Marinomonas mediterranea MMB-1
Genome accession: NC_015276
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1205406 - 1206812 bp
Length : 1407 bp
Strand : -
Note : SMART: ATPase, AAA+ type, core; TIGRFAM: ATPase, type III secretion system, FliI/YscN; KEGG: epy:EpC_30890 hrp/hrc type III secretion system-Hrp/hrc secretion/translocation pathway-HrcN protein; PFAM: ATPase, alpha/subunit beta, nucleotide-binding domain;

DNA sequence :
ATGTTAAACAGCCACAACATGACACAGCAATCGAACGATGACACACGTCACAGCGACATTAAACAACGTTTAAAAAATTG
GTCCTCAGAACGATTGCAGACAGTACAAGACGAGCCAATTGTGAAAGTGATAGGACGTGTCACAAAAATCAACGGCATAT
TAGTAGAAAGTCGTATTGCGGACGCTCGGATCGGAGATTTATGTACGATCCAAGGGCGTGGCAATCATCGTGTCCTTGCG
GAAATCATCGGATTTAGCTCAGACATTGTTTTACTATCGGCATTAGGTGCATTAGAAGGTATATCCGTTGGCGCATCGAT
CATGCCTCATTATCAAGCCCATTGTATTGATAGTGACGAGTCATTACTCGGGTCCGTTTTAGATGGCTTTGGCCGCTTGC
TTCAAGGAAAGCGCGACGCCTTCACCCTAGAAGAAAGCGAGCACACCAGCAAAGTGATTCGGGATGCTATTGCCCCCACC
CAACGCCCCAGAATCAGCGCTCCTATGCCCACAGGGGTAAGGGCGATAGATGGCCTATTAACCATAGGTGAAGGGCAAAG
AATCGGCGTATTCGCTGGAGCGGGTTGCGGTAAAACCACGCTACTTGCTGAGCTTGCCCGCAATATGCCATGCGACGTGA
TTGTCTTTGGATTGATCGGTGAACGAGGTCGTGAACTGCGAGAGTTTTTGGACCACGAATTGGATGAAGAACTGCGCAGT
CGCTCAGTACTCGTTTGCTCTACCTCTGACCGAACCAGTATGGAGCGAGCAAGAGCTGCCTCCACTGCAACCGCAATTGC
AGAAGGGTTTCGTGCACAGGGTAAACGTGTTCTGTTACTCATTGACTCCCTTACCCGATTTGCCAGAGCGCAACGCGAAA
TAGGACTCGCAGCGGGCGAGCCGCCAGGACGAGGTGGCTTCCCCCCTTCTGTTTATACTATGTTGCCACGCTTAGTCGAA
CGCGCCGGTAATATGGAAGGTGCAGGGTCAATCACCGCGCTTTATACCGTCTTGATTGAAGGCGATGTGATTGCTGGCGA
CCCTGTTGCCGATGAAGTCCGATCTCTGCTCGATGGCCATATTATATTGTCACGTAAACTGGCAGAGAAAAATCATTACC
CTGCCATTGATGTGCTGGGCAGCATCAGCCGAACCATGCCAAATGTCACCGACCCGAACCATATCCAGTCCGCTGCCGTG
CTCAGAAATCTCATGTCCGCTTATAAAGAAGTGGAAATGTTGATCCGACTAGGCGAATACGAACAAGGGAATGATCCGCT
AACTGACACAGCGGTTGCGTTAAACGGAACCATTTTAGAGTTCCTCCAGCAATCGATGCGCTCACCTAGCTCGATTCAAG
ATACGCTTCACGCTCTCTCGAGTATCTCTCAACATGCAGCGACCTAG

Protein sequence :
MLNSHNMTQQSNDDTRHSDIKQRLKNWSSERLQTVQDEPIVKVIGRVTKINGILVESRIADARIGDLCTIQGRGNHRVLA
EIIGFSSDIVLLSALGALEGISVGASIMPHYQAHCIDSDESLLGSVLDGFGRLLQGKRDAFTLEESEHTSKVIRDAIAPT
QRPRISAPMPTGVRAIDGLLTIGEGQRIGVFAGAGCGKTTLLAELARNMPCDVIVFGLIGERGRELREFLDHELDEELRS
RSVLVCSTSDRTSMERARAASTATAIAEGFRAQGKRVLLLIDSLTRFARAQREIGLAAGEPPGRGGFPPSVYTMLPRLVE
RAGNMEGAGSITALYTVLIEGDVIAGDPVADEVRSLLDGHIILSRKLAEKNHYPAIDVLGSISRTMPNVTDPNHIQSAAV
LRNLMSAYKEVEMLIRLGEYEQGNDPLTDTAVALNGTILEFLQQSMRSPSSIQDTLHALSSISQHAAT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-119 66
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-134 66
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-115 65
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-125 64
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-125 64
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-123 64
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-132 64
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 9e-129 63
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-129 63
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-129 63
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-115 61
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-115 61
lscN AAO18044.1 LscN Virulence TTSS locus Protein 8e-94 53
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 49
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-84 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-77 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-77 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-77 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-77 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-78 49
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-84 49
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-84 49
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-84 49
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-84 49
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-84 49
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-81 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-81 48
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-74 48
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-74 48
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 5e-73 48
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-73 48
escN AAC31513.1 L0034 Virulence LEE Protein 6e-73 48
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 6e-73 48
escN AAK26715.1 EscN Virulence LEE Protein 5e-73 48
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-72 48
escN AAL57542.1 EscN Virulence LEE Protein 5e-73 48
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-72 48
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-73 48
escN NP_290268.1 hypothetical protein Virulence LEE Protein 8e-73 48
escN AAC38383.1 EscN Virulence LEE Protein 1e-72 48
ECs4568 NP_312595.1 EscN Virulence LEE Protein 8e-73 48
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-72 47
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-76 46
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-70 44
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 8e-70 44
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-70 44
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-70 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-65 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-63 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-66 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG0390 Protein 2e-89 52
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG0192 Protein 4e-90 52
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG0048 Protein 5e-91 51
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG0515 Protein 1e-77 49
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG0730 Protein 7e-73 48
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG0812 Protein 4e-73 48
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG1254 Protein 1e-75 47
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG0555 Protein 4e-70 44
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG2144 Protein 8e-86 44
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG1008 Protein 3e-67 44
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG2331 Protein 3e-73 43
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG2459 Protein 2e-65 42
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG1778 Protein 2e-64 42
Marme_1076 YP_004312187.1 FliI/YscN family ATPase VFG2499 Protein 3e-70 41