Gene Information

Name : Clole_0608 (Clole_0608)
Accession : YP_004307540.1
Strain : Clostridium lentocellum DSM 5427
Genome accession: NC_015275
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 764456 - 764944 bp
Length : 489 bp
Strand : -
Note : KEGG: bld:BLi02319 DfrA; PFAM: dihydrofolate reductase domain

DNA sequence :
TTGATTTGTTTAATCGCAGCTGTTAGTAAAAATAATCAAATTGGACTTCACAATCAAATGCCTTGGCATATTCCTGAAGA
CCTAGCTTATTTTCGTGAAGTAACAAGTGGGCATACTGTTATCATGGGAAGAAAGACCTTCGAAAGCATAGGTAAACCTC
TCCCCCATAGAACCAATATGGTTTTAACTACAAACCCTAACTTCTCTGCGGAGGGTGTTGTTGTTTTGCATAGCTTAAAT
GAAGCATTAGAGTTATGCAAAACAACAACAGAAGCAGTTTTTGTAATTGGTGGTGGTGAAATTTATAAAGCCTTTTTACC
TTTCGCAGAATATTTATACATTACTTTAATTGATGAAGTTGTTGAGGGTGATACTTGCTTTCCCGATTATCAAAAAGATT
TTCAATTGATAAAATCCACTTGTAGTAAGTCGCAAACATCTACTGGTCATTATTTTTTCTTTACTCTTTGGAAAAGAATA
GGTCATTAA

Protein sequence :
MICLIAAVSKNNQIGLHNQMPWHIPEDLAYFREVTSGHTVIMGRKTFESIGKPLPHRTNMVLTTNPNFSAEGVVVLHSLN
EALELCKTTTEAVFVIGGGEIYKAFLPFAEYLYITLIDEVVEGDTCFPDYQKDFQLIKSTCSKSQTSTGHYFFFTLWKRI
GH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
folA-2 YP_189146.1 dihydrofolate reductase Not tested ¥ÕSP¥â Protein 2e-25 47
dfrA15 AGK07099.1 DfrA15 dihydrofolate reductase Not tested SGI1 Protein 2e-17 41
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 1e-23 41