Gene Information

Name : Clole_4170 (Clole_4170)
Accession : YP_004311040.1
Strain : Clostridium lentocellum DSM 5427
Genome accession: NC_015275
Putative virulence/resistance : Resistance
Product : Cys/Met metabolism pyridoxal-phosphate-dependent protein
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 4594485 - 4595609 bp
Length : 1125 bp
Strand : +
Note : PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: gwc:GWCH70_2474 cystathionine beta-lyase

DNA sequence : 
ATGAAATTTGAATCAAAGGTTATCCATGGTGGTATCTCTGAAGATGCCTTTACAGGCGCAGTTAATATTCCTATTTATCA
AACATCTACTTTTAGACAAGAAGGGATTGGTAAACATAAAGGCTTTGAATATGCACGCACAGGTAATCCTACAAGACAGG
CTTTGGAAGAGCTTATTAAAGATCTAGAAGGTGGCATCGCTGGTTTTGCTTTTGCTTCTGGTTTAGCCGCTCTTTCTACA
GTCCTTATGCTTTTTAAAACAGGAGACCATATTCTTCTATCTGATAATGTCTACGGTGGTACTTTTCGAGTAGTCGATAA
GGTATTCGTTCATCTTGGTATTTCTTATTCTCTAGTAGATACTTCCGACCTTGAAGCTGTTCAAAAAGCTATCACGCCTA
CTACTAAAGCCATCTTTATTGAAACACCTACTAATCCATTAATGAAAATCACAGACCTATCAGCGATTAGTACACTTGCC
AAAAGTCATAACCTCATTTCGGTTGTTGACAACACGTTTTTAACCCCTTATCTTCAACGTCCTATAGAACACGGCATAGA
CATTGTTGTTCATAGCGGCACCAAATATTTAGGCGGACATAGTGATGTAGTTGCTGGGCTTGTAGTTGTTGCTCATGAAG
ACCTTAAAGAACGACTTGGCTTTTTACAAAATGCTGTAGGTGGGATACTTGGTCCCCAAGATAGCTTTTTACTTATAAGA
GGTATTAAGACACTGGCTATTAGATTAGAAAAGGCTCAAGCTAATGCTAAAGCGATTGTTGATTTCTTACACACTCTACC
TCAGGTAAGTAAAATCTATTATCCAGGTTTAGGCGCTATGATTTCTTTTGAACTTAGTGACCCCGAGGTCGCTCTAAAGC
TCGTAGAAAATGTTAAACTCATTGCTCTGGCAGAAAGTCTAGGAGGTGTAGAAAGTCTTATTTGCCTTCCAGCAGCTATG
ACACATGCCTCTATTCCCGTAGAACAAAGAAAGGCCTTAGGTATAACAGATGGTTTACTTCGTCTTTCTGTAGGCATCGA
AGATGCTGACGACTTGATAACTGATTTAACCCATGCACTTAATCTTTCTATCTCTGAAGGAGGTACATCTCATGCACTAT
ATTAA

Protein sequence : 
MKFESKVIHGGISEDAFTGAVNIPIYQTSTFRQEGIGKHKGFEYARTGNPTRQALEELIKDLEGGIAGFAFASGLAALST
VLMLFKTGDHILLSDNVYGGTFRVVDKVFVHLGISYSLVDTSDLEAVQKAITPTTKAIFIETPTNPLMKITDLSAISTLA
KSHNLISVVDNTFLTPYLQRPIEHGIDIVVHSGTKYLGGHSDVVAGLVVVAHEDLKERLGFLQNAVGGILGPQDSFLLIR
GIKTLAIRLEKAQANAKAIVDFLHTLPQVSKIYYPGLGAMISFELSDPEVALKLVENVKLIALAESLGGVESLICLPAAM
THASIPVEQRKALGITDGLLRLSVGIEDADDLITDLTHALNLSISEGGTSHALY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-90 53
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-89 52
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-64 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Clole_4170 YP_004311040.1 Cys/Met metabolism pyridoxal-phosphate-dependent protein BAC0207 Protein 3e-61 42