Gene Information

Name : YE105_C0310 (YE105_C0310)
Accession : YP_004296511.1
Strain : Yersinia enterocolitica 105.5R(r)
Genome accession: NC_015224
Putative virulence/resistance : Virulence
Product : Multi-sensor hybrid histidine kinase
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0642
EC number : -
Position : 386481 - 389261 bp
Length : 2781 bp
Strand : -
Note : -

DNA sequence :
ATGGAAAAATCATCATCACTCGTCACTCGATTGACACTATTACTGGGTATGACCTTAACGGCTATTTGGTTAATTTCAAT
TGCCATGACAGCATTCTTCTCATATGAAGATACGCGTCAACGTTTGGTGAGTGAGTTAACACACATGGCATCATTACGAG
CAGATTTAAGTAATTACCAATTTGAAGGGGCAGAAAGGGATGCTCTTTCATTGATCAACCGCCAGGATCATAACCAAATG
AGCTGGGGATTCCCTATACCAATCAAAAATGAGAGCGTAAAAAATAACACTCTTATTAATTCGATAACTTGTTCCCCCAC
TCAATCTAAGCATGATTTGCAGATAAAACAGGCTTACGGCACGTCAGGCCAGACATATTATCTTGATAGTTTTGCGATTA
AGAACAATGATGGAATTACTATCTTTAAACCGCAAAATGTTTCCAGCGACTATTTGAAGCAACGACGTAAAGAGTTACTT
TTGCTTCCCATATTTCCTACTCACAATAATATTTTTTGGGGAATGCCCACTTACACTCAGCAAAATGGCTGGCATGTTTC
TGTTGCTGCATGTGATCAAATGGGATCATTAGCGGGATTTTCATTAAAACTGAATGAATTAGTAACTAATAATCAATCAT
TTGATCAGCGGGATATCAATTTATTACTGGATAAAGAAGGAAAATTATTACCTCTTTCTCAACAAAACATACCGTCAAAT
CAGTTATACGAAATCCTCCGCCAACTGAAAAATATTCACTTACACGATGGCTGGCAACAAACACCCGATTATTTGGTACT
AAGAACTCAGCTAAAAGGCCCCGGCTGGCAGCAATTAGTGATTTATCCACGGATAGGATTCGCTTGGGAGGCCGCAAAGC
CCGCATTACATCAACTCCCCTTTGCTTTGGCTATTTTACTGCTCCTTACCTTAGCGCTTTCTTTATTACTGCGATATTAC
CTGGCCATTCCATTATGGAACTTTGTCAATATTATCGGATCCACTGGGCCACAAGCTATGGAGCCACGATTACCTGTTAA
ACGTATGGATGAATTAGGCCACATTGCTCGTGCCTACAACGGCTTATTAGATAATTTGAATGAGCAATACGACACATTAG
AAATGAAAGTAAAAGAACGGACATTGGCGTTGGCGAAATCAAAATTAGCTGCGGAACAAGCAAACCATCGAAAAAGTATA
CATTTGACCACCATAAGTCATGAGATCCGAACCCCCTTAAATGGAGCTTTAGGTGCCGTCGAGTTATTACAAAATACTCC
CTTGGCTCCGGAGCAATATCAGTTAGCAGAGACCGCACGTCAGTGTTCACATTCATTGTTGGCAATAATCAATAACCTCC
TGGACTTCTCGCGTATTGAATCCGGTCAATTAACCTTGTCACAGGAGAAAACAGCGCTATTACCTTTACTGGACCAGGCA
ATGTTAACCATACACAGCCAAGTCTTAAATAAACCTATCGCGCTCTCTACTTATGTCAGCTCAGACGTACCATTAGAAAT
TGAGCTGGATAGTCAGCGCATAAAGCAAATTCTGGTAAACCTATTGGGTAATGCCGTTAAATTTACGCGGCAAGGTCATA
TTAGTCTCACTGTTGAACGCAAAGGTCAGCAACTCTGTTTTACCGTTGAAGATACCGGTTGTGGCATTGATTCACAGCAT
CAGGAAAAGATATTCCGCCCCTTTATTCAAACTTATGATCATAGGCAAGGAACCGGCTTAGGGCTGACTATTGCAGATAA
TCTGGCAAAAATGATGGGTGGAAATATTACGCTATATAGTAAGCCTAATTGTGGCAGTCATTTCTCATTAACTCTACCGT
TTAGAGGGACAACTCCAGTAATGTCTTTTAAGAATGTGTGCTATGCGGCCCCCTCATCGTTACAGGCACAATTATCTGCC
TGGGGCATAACCTGCCAACCGATGAATCATAAATCGATTAGCCTGCCGCTCGGGCTGTTCTCTGATAAAGAATTGTGTTA
TCTACCCGGCCGTTTATATACCAAGGTAAAACACTATTTGGACAATAAAGGATGCGCGCCTCCTTACCTGCAACAGATAC
AACATCATCTTCCGCTGCAACCCTGGCATATGAGTATATTGCTGGTCGATGATGCAGAAACCAATCGTGATATTACTGGC
ATGATGCTGCGACAACTGGGGCATCAGGTTACGTTGGCCGAAAGTGGCGAAATTGCACTGCATATCGGGCAAGGCCAATA
TTTTGATCTGGTGCTAATGGATATTCGTATGCCGGGAATGGATGGCCTGACAGCAACCCAGCATTGGCGTAACGATACAA
TTAATTTAGATAACCGCTGCATGATAACGGCACTTAGTGCGAATACTAACCCAGATGAAAAAATAAAGGCCTATCAGGCA
GGGATGAATCATTATATTTCTAAGCCAGTGACGTTCAATCAACTGGCAGAAGTTCTGGATCTGACGGCACAATTTCAGCT
AGAACGTGGGATTAATCTCACTCCGCAAGTGACCACCGCCAAACCATTATTGAACCTGGCAGACGACTCACTCCGTCTTA
AATTATCGAAATCACTGCAAGAGTTACTGCAACTGGCAAGAGACTCTCTTACTCATATCCCAACCCTATCGGACCATCTT
CACACTCTAAAAGGGTGTGCCGGGCAAGCAGGCTTAATTGAATTACAAGAAGCTGTTATTCAGTTGGAAATAGCCATTGA
AGCAAAGGAAAGGATTACTCAACGAGATATCACTCGCCTCGACGAGATAATCCATTGGTAA

Protein sequence :
MEKSSSLVTRLTLLLGMTLTAIWLISIAMTAFFSYEDTRQRLVSELTHMASLRADLSNYQFEGAERDALSLINRQDHNQM
SWGFPIPIKNESVKNNTLINSITCSPTQSKHDLQIKQAYGTSGQTYYLDSFAIKNNDGITIFKPQNVSSDYLKQRRKELL
LLPIFPTHNNIFWGMPTYTQQNGWHVSVAACDQMGSLAGFSLKLNELVTNNQSFDQRDINLLLDKEGKLLPLSQQNIPSN
QLYEILRQLKNIHLHDGWQQTPDYLVLRTQLKGPGWQQLVIYPRIGFAWEAAKPALHQLPFALAILLLLTLALSLLLRYY
LAIPLWNFVNIIGSTGPQAMEPRLPVKRMDELGHIARAYNGLLDNLNEQYDTLEMKVKERTLALAKSKLAAEQANHRKSI
HLTTISHEIRTPLNGALGAVELLQNTPLAPEQYQLAETARQCSHSLLAIINNLLDFSRIESGQLTLSQEKTALLPLLDQA
MLTIHSQVLNKPIALSTYVSSDVPLEIELDSQRIKQILVNLLGNAVKFTRQGHISLTVERKGQQLCFTVEDTGCGIDSQH
QEKIFRPFIQTYDHRQGTGLGLTIADNLAKMMGGNITLYSKPNCGSHFSLTLPFRGTTPVMSFKNVCYAAPSSLQAQLSA
WGITCQPMNHKSISLPLGLFSDKELCYLPGRLYTKVKHYLDNKGCAPPYLQQIQHHLPLQPWHMSILLVDDAETNRDITG
MMLRQLGHQVTLAESGEIALHIGQGQYFDLVLMDIRMPGMDGLTATQHWRNDTINLDNRCMITALSANTNPDEKIKAYQA
GMNHYISKPVTFNQLAEVLDLTAQFQLERGINLTPQVTTAKPLLNLADDSLRLKLSKSLQELLQLARDSLTHIPTLSDHL
HTLKGCAGQAGLIELQEAVIQLEIAIEAKERITQRDITRLDEIIHW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0256 YP_002345336.1 two-component sensor/regulator Not tested Not named Protein 0.0 71
spiR AAC44299.1 SpiR Virulence SPI-2 Protein 3e-128 44
ssrA NP_456136.1 putative two-component sensor kinase Virulence SPI-2 Protein 7e-133 43
ssrA NP_805063.1 two-component sensor kinase Virulence SPI-2 Protein 2e-133 43
ssrA YP_216400.1 secretion system regulator:sensor component Virulence SPI-2 Protein 1e-132 43
ssrA NP_460357.1 sensor kinase Virulence SPI-2 Protein 1e-131 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YE105_C0310 YP_004296511.1 Multi-sensor hybrid histidine kinase VFG0493 Protein 5e-132 43