Gene Information

Name : NAL212_2096 (NAL212_2096)
Accession : YP_004295091.1
Strain : Nitrosomonas sp. AL212
Genome accession: NC_015222
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2065673 - 2068255 bp
Length : 2583 bp
Strand : +
Note : TIGRFAM: Chaperonin ClpB; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; KEGG: nmu:Nmul_A1541 ATPase with chaperone activity; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGCGTTTTGACAAACTGACCACCAAATTCCAACAAGCATTTGCTGATGCACAAAGCATCGCTGTCGGCCAGGACAACCC
AACTATAGAACCCCAGCACTTGTTACTGGCATTATTGCAACAGGATGATGGCAGTACGCTGTCACTATTGCAACGCTCTG
GCGTTAATACCACGCCCTTGCTGGAGAACATCAAGCAAACTATTTACCGCTTGCCGAAGGTTGAGAATTCAGGTGGTGAG
GTGACGATTTCCCGTAGCCTGAATAATCTGCTCAACGTAGCTGATAAAGAAGCGCAAAAACGCAACGATCAGTTTATTGC
CTCTGAGATGTTTCTTTTGGCCGTCTTGCAGGATAAAGGCGAAGTAGGCGCATTGTTAAAACAGTATGGCGCCAACACCG
CAGCTTTGGAGAAAGCGATTAATGCAGTACGGGGGGGCGAGCAGGTGGGGAGCGCTGAAGCTGAAGGCAACCGTGAAGCA
TTGAAAAAATACACCCTGGATCTTACTGAACGTGCGCGCCAGGGCAAACTGGATCCGGTTATAGGGCGTGATGATGAGAT
CCGTCGGGCCATTCAGGTGTTGCAGCGGCGTACCAAAAATAATCTCGTTCTGATTGGTGAGCCCGGAGTGGGTAAAACCG
CGATTGTTGAAGGCCTGGCACAACGCATCATCAATGGAGAAGTACCTGAAAGTTTGAAAGACAAACGTGTTCTTGTTTTG
GATATGGCAGCGTTACTGGCCGGTGCAAAATACCGCGGTGAATTTGAAGAGCGCCTCAAATCGGTGCTGAAAGAACTGGC
ACAAGACGAAGGTAAAACCATTGTATTCATCGATGAACTGCATACCATGGTAGGTGCCGGCAAAGCAGAAGGCGCCATGG
ATGCGGGCAATATGTTGAAGCCAGCCTTAGCACGCGGAGAATTACATTGTGTTGGCGCAACAACACTCGATGAGTATCGC
AAGTATATTGAAAAAGATGCTGCGCTAGAGCGGCGTTTTCAAAAGGTCCTTGTAGAAGAACCCAGTGTGGAAGTTACCAT
TGCAATATTACGCGGCTTACAAGAAAAATACGAAGTACATCATGGAGTAGATATTACTGATCCCGCCATTGTTGCTGCCG
CGGAATTATCCAATCGGTATATTACCGATCGTTTCCTGCCTGACAAAGCCATTGATCTGATAGACGAAGCAGCGGCAAGA
ATTCGTATGGAAATAGATTCTAAACCCGAGATATTGGATAAGCTGGATCGGCGCTTGATACAGCTAAAAATTGAGCGTGA
AGCAATTAAAAAGGAAAAAGATGAGGCATCACAAAAACGTCTTCAATTATTGGAAGAGGAAATCAAACACAAAGAACGAG
AATATGACGATTTAGCCGAGATCTGGAAAGCTGAGAAATTTCAGGTGCACGGCTCTCAGCAAATCAAGGAAGCAATGGAG
AAACTTAAGCTGGAAATAGAAGCAGCCACTCGTAAAGGAGATTGGCAAAAAGTTTCAGAATTGCAATATGGCCGCCTACC
GCAGCTGGAAGCACAATTGCAGCAGACTGCAGGAAATGAATCAACTTCTGCACTGACGCCTAGATTGTTGCGGACTCAGG
TAGGTGCTGAAGAAATTGCAGAAGTGGTATCTCGCGCCACCGGGATTCCTGTGTCGAAAATGATGCAAGGTGAACGGGAA
AAATTGCTTCTGATGGAACAAAAACTTCATGATCGAGTGGTGGGTCAGGATGAAGCCGTACGGCTGGTTTCGGATGCCAT
TAGACGTTCCCGTGCCGGCTTGGCGGATCCCAATCGTCCTTATGGATCGTTCTTGTTTCTGGGACCCACCGGGGTAGGAA
AAACGGAACTATGCAAAGCGCTGGCTGGTTTTCTATTTGATTCCGAGGACCATCTCATTCGTGTCGACATGTCTGAATTC
ATGGAAAAACATTCTGTCGCACGATTGATTGGCGCTCCACCGGGCTATGTCGGCTATGAAGAAGGCGGTTACTTAACCGA
GCTCGTGCGCAGAAAACCTTATGCGGTTATTTTGCTGGATGAGGTTGAGAAAGCGCACCCGGATGTATTTAATGTTTTGC
TGCAAGTTCTGGACGACGGACGAATGACGGATGGTCAGGGACGCACAGTCGATTTCAAAAATACAGTGATCGTCATGACA
TCCAATTTGGGATCCCAGATGATTCAGGAAATGTCAGGAAATGAGTATCAGGCGATCAAACAGGCCGTCATGAATGAAGT
GAAAACATACTTTCGTCCCGAGTTTATTAATCGCATCGATGAAGTTGTTGTGTTCCATGCATTGGGTGAGAAGCACATCC
ACTCGATTGCCCGGATACAATTGCATTCCCTTGAAGCGAGACTCGCCAAACTGGAAATACAGTTGATAGTCAGTGAAGCA
GCACTCACCGCCCTTTCTCAAGCAGGATTCGACCCGGTATTTGGTGCACGCCCTTTAAAACGAGCCATTCAAACACAAAT
TGAAAATCCTTTGGCCAAAGAAATTTTGGAAGGGAAATTTGTTGCAAAAGATATCATCCAGGTCGACTACCACGATGGCA
TGATCAGTTTCAGCAAAAAGTAG

Protein sequence :
MRFDKLTTKFQQAFADAQSIAVGQDNPTIEPQHLLLALLQQDDGSTLSLLQRSGVNTTPLLENIKQTIYRLPKVENSGGE
VTISRSLNNLLNVADKEAQKRNDQFIASEMFLLAVLQDKGEVGALLKQYGANTAALEKAINAVRGGEQVGSAEAEGNREA
LKKYTLDLTERARQGKLDPVIGRDDEIRRAIQVLQRRTKNNLVLIGEPGVGKTAIVEGLAQRIINGEVPESLKDKRVLVL
DMAALLAGAKYRGEFEERLKSVLKELAQDEGKTIVFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
KYIEKDAALERRFQKVLVEEPSVEVTIAILRGLQEKYEVHHGVDITDPAIVAAAELSNRYITDRFLPDKAIDLIDEAAAR
IRMEIDSKPEILDKLDRRLIQLKIEREAIKKEKDEASQKRLQLLEEEIKHKEREYDDLAEIWKAEKFQVHGSQQIKEAME
KLKLEIEAATRKGDWQKVSELQYGRLPQLEAQLQQTAGNESTSALTPRLLRTQVGAEEIAEVVSRATGIPVSKMMQGERE
KLLLMEQKLHDRVVGQDEAVRLVSDAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRVDMSEF
MEKHSVARLIGAPPGYVGYEEGGYLTELVRRKPYAVILLDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMT
SNLGSQMIQEMSGNEYQAIKQAVMNEVKTYFRPEFINRIDEVVVFHALGEKHIHSIARIQLHSLEARLAKLEIQLIVSEA
ALTALSQAGFDPVFGARPLKRAIQTQIENPLAKEILEGKFVAKDIIQVDYHDGMISFSKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-156 45
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 9e-105 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NAL212_2096 YP_004295091.1 ATP-dependent chaperone ClpB VFG0079 Protein 2e-165 49
NAL212_2096 YP_004295091.1 ATP-dependent chaperone ClpB VFG2076 Protein 3e-107 44