Gene Information

Name : NAL212_1718 (NAL212_1718)
Accession : YP_004294753.1
Strain : Nitrosomonas sp. AL212
Genome accession: NC_015222
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1667182 - 1668888 bp
Length : 1707 bp
Strand : -
Note : TIGRFAM: Urease, alpha subunit; KEGG: nmu:Nmul_A1241 urease subunit alpha; PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal

DNA sequence :
ATGAGCGTAAAAATTTCCCGTCGAAACTATGCTGAGATGATGGGCCCCACGACCGGGGATCGTGTTCGTCTGGCCGATAC
AGAACTATTTATAGAAATTGAAAAAGATTTCACTACATATGGTGAAGAGGTGAAATTCGGTGGTGGTAAAGTGATTCGGG
ATGGTATGGGACAATCACAGCGAAATCATGCGGATGTTATGGATACCGTCATTACCAATGCAATTATTATCGATCACTGG
GGGATTGTAAAAGCGGATATAGGGATCAAGAATGGCAAAGTAGCTAATATCGGAAAAGCCGGTAACCCGGATATTCAGCC
GAATGTTACGATGGCAATTGGCTCAGCGACTGAGATTATTGCTGGTGAAAATTCGATTGTTACCGCAGGCGGTGTTGATA
CCCATATTCACTTCATTTCTCCGCAACAAGCCGAAGATGCCATGATGAACGGCATCACTACCATGTTGGGTGGCGGTACC
GGACCTGCAGTAGGAACAGCGGCAACTACCTGTACGCCCGGTCCCTGGCATATTCATTCGATGCTAAGGGCATCGGACGG
GTTAGTAATGAATACAGGTTTTTTCGGTAAAGGTAATACCAGCTTGCCTACACCGCTTGAAGAGCAAGTACTTGCCGGTG
CTTGTGGTCTGAAGCTTCATGAAGATTGGGGTACCACATACGCCGCGATCGACAATTGCTTGGATATTGCGGATAAATAT
GATGTACAGGTCGCAATCCATACCGATACCATTAATGAAGGCGGATATTTGGAGAATACCATTGCTGCCATGAAAGATCG
CACTATTCATACTTTCCACACCGAAGGTGCGGGTGGAGGGCATGCTCCGGATATTATCGCGGTTGTTGGTCAGGAAAATG
TTTTACCATCGTCTACGAATCCGACTCGTCCTTATACGGTCAACACTCTTGATGAGCATTTGGATATGTTGATGGTGTGC
CATCATTTACATGCCAATATTCCGGAGGATGTTGCCTTTGCAGAGTCACGTATCCGTAAAGAAACGATTGCCGCTGAGGA
TATTTTGCATGATATGGGGGCAATTTCTATGATGTCCTCAGATTCACAGGCGATGGGGCGTATTGGTGAAGTTGTATTGC
GTACATGGCAAACCGCGCATAAAATGAAAATACAACGCGGAACATTGCAAGAAGATAATTCGAGGAATGATAATTTTCGT
GTCAAGCGCTATGTTGCCAAATACACGATTAATCCAGCTATCACACACGGTATCGCGCACGCAATTGGTTCGATAGAAGT
CGGTAAATATGCGGATCTTGTATTATGGAGGCCAGCCTTTTTCGGCGTAAAACCATCCATGATATTGAAAAGTGGAATGA
TTGCAGCATCGCTGATGGGTGATCCTAATGCATCGATTCCAACACCTCAGCCAGTACATTATCGCTACATGTTTGGAGGA
TATGGGGGCGGGATCAAAACATCGTGTTTCACATTTGCTTCGCAAGCCGCGCTTAATGCTAATTTAATTGATCAACTGAA
GTTGGACAAAAATATTATTGCGGTAAAGAATACCCGAAACTTGCGCAAGAAAGACATGATTCACAATAGCGCGACACCTA
AGATGGAAGTTGATCCGGAAACCTATGAAGTCCGTGCGGATGGACAATTGCTGACATGCGGCGCTGAAGATGTATTACCA
ATGGCACAACGTTACTTTCTGTTTTAG

Protein sequence :
MSVKISRRNYAEMMGPTTGDRVRLADTELFIEIEKDFTTYGEEVKFGGGKVIRDGMGQSQRNHADVMDTVITNAIIIDHW
GIVKADIGIKNGKVANIGKAGNPDIQPNVTMAIGSATEIIAGENSIVTAGGVDTHIHFISPQQAEDAMMNGITTMLGGGT
GPAVGTAATTCTPGPWHIHSMLRASDGLVMNTGFFGKGNTSLPTPLEEQVLAGACGLKLHEDWGTTYAAIDNCLDIADKY
DVQVAIHTDTINEGGYLENTIAAMKDRTIHTFHTEGAGGGHAPDIIAVVGQENVLPSSTNPTRPYTVNTLDEHLDMLMVC
HHLHANIPEDVAFAESRIRKETIAAEDILHDMGAISMMSSDSQAMGRIGEVVLRTWQTAHKMKIQRGTLQEDNSRNDNFR
VKRYVAKYTINPAITHGIAHAIGSIEVGKYADLVLWRPAFFGVKPSMILKSGMIAASLMGDPNASIPTPQPVHYRYMFGG
YGGGIKTSCFTFASQAALNANLIDQLKLDKNIIAVKNTRNLRKKDMIHNSATPKMEVDPETYEVRADGQLLTCGAEDVLP
MAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-178 68
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-178 68
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-163 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-164 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 6e-164 64
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-164 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NAL212_1718 YP_004294753.1 urease subunit alpha VFG0270 Protein 2e-151 61