Gene Information

Name : Metbo_1239 (Metbo_1239)
Accession : YP_004290453.1
Strain : Methanobacterium sp. AL-21
Genome accession: NC_015216
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.3
Position : 1242785 - 1244833 bp
Length : 2049 bp
Strand : +
Note : TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: mst:Msp_0121 cation transport ATPase; PFAM: ATPase, P-type, ATPase-associated domai

DNA sequence :
ATGCCAAAGAATAACAAACACAATCATGAACACAACCAGGAAAACTGTGAATCAAATGAAGAATCAACCAACAACAATAA
ACTAGATAATTGTGGCTGCGAAGGTGAAACTTGCAATGTAAATGGTGATAACTGTAATGATGGAACATGTGGATGTAGTT
GTGAAGAAGACCTTTTAGAGGAAAAGGAACAGTTATGGGACAGAAAACCCCTTATGGTCATAACTCTATCAGGAATATTC
CTCTTTGCAGCACTGTACTTAGACTTATCAGGATATGGATCATTAACTACTACACCATTATTCCTGATTGTGGTTTTGCT
CTCGGGATATAATGTGGTAAAAAATGGTATAATTGCTCTTTTTAAGGGAAATTTTACCATGAACTTTTTAATGACAATAG
CCGTGTTCGGTTCATTTTTAATAGGTTCTGGAGCTGAAGGTGCAGTTGTAATATTCCTATTTTACATAGCACTCTACCTT
GAAAACTATGCCGGAGAAAGGGCTCGAAAATCAATAGCATCCCTATTAAAATTGGTACCAGAAACAGCAACTTTGAAAAA
AGATGGATTAACCTCTGAAATTCATGTTCATGATGTAAAAGCTGGAGACATTCTGGTTGTAAAACCTGGAGACAAAGTCC
CAATTGATGGTAAAGTAATCAAGGGCTCAACTTCAATAAACCAAGCAGCAATTACTGGTGAAAGTGTACCTGTAAATAAA
AATATAGGGGATGATATTTTTGCAGGAACTTTGAATCAAGAGGGTTACATTGAAATGGATGTCACTAAAGAGTCGGATCA
AACAGTTCTATCAAAGATCGTCAAGCTGGTTAAAGAATCACAGAAAAAAAGGTCAAATACTGAAAATTTCATTGATAAAC
TGGCAAAATATTATACTCCTGCTGTTATAGGACTCGCAGCTTTAGTTGCAATAATTCCGGTTGTATTCTTTGGACAATCT
ATAGATGAATGGGTTTATAGAGCACTGGTACTGTTAATAATATCTTGTCCTTGCGCATTTTTATTATCAACACCAGTTGC
CATGGTATCAGGAATAACAGCAAGTACGAAGAACGGAGTTTTAATAAAAGGTTCAAGATACGTCGAAGAAATGAGCAAGA
TAAAGGTCATGGTGTTTGATAAAACTGGAACATTGACACAGGGAAATTTAGAGCTAACTGATATAATAGCATTGAACAAT
TACTCGAAGGCTGAAATATTGATGGTTGCAGGTTCATTAGAATCAAATTCAAACCATCCAATAGGAAATGCCATAAGTAG
CTATGTCAAAGGGCAGGGTGTTAAACTCAGTGAAGTAAAGGATTTCAAGTCCATTACTGGAAATGGTTTAAAAGGAACCC
TCGATAATAAAACCTATATTTTGGGTAAGAAGAATTTATTTAGCAATAAATATGAATTTTCCGATACAATGATTCGGGGA
TTTGAAGATCAAGGAAAAACAGTGGTTTTAATTGCTAATGAAACTGAGATATTAGGTTTTATTTGTATGAAGGATACTGT
GCGAATAGCTTCTAAAAGCACAATATCAAAGCTGAAGAACAGTGGAATAAAAACAGTCATGCTCACTGGAGACAATGAAC
AAACTGCAAAAACTGTTGCTGATGATATTGGTCTTGATGAATATTATGCCGAATTATTACCAGAGGATAAAGTAAAAATC
ATTGAAAAGTATATTGATAAAGGAATTGAAGTTGCTATGGTTGGTGATGGAGTGAATGATGCTCCAGCCCTTGCAAGATC
TAATGTGGGTATTGCAATGGGGGCCGCAGGTTCGGATGTTGCAATTGAAACTGCAGACATAGCTCTCATGCACGATGATA
TTAGTAAAATCAACTACCTTCTGAATCTAAGCAGAAAAACAATGGGGGTTGTTAAACAGAATGTTTCTGTTGCACTCATA
ATCCAAGTATCACTATCTGTACTTGCAGTGTTTGGTTATGTTTCATTGTGGATGGCAGTAACATTTGGAGACATGGGACT
TACACTTGCAGTAATATTAAACTCCCTAAGACTTGTATACACTAAATAA

Protein sequence :
MPKNNKHNHEHNQENCESNEESTNNNKLDNCGCEGETCNVNGDNCNDGTCGCSCEEDLLEEKEQLWDRKPLMVITLSGIF
LFAALYLDLSGYGSLTTTPLFLIVVLLSGYNVVKNGIIALFKGNFTMNFLMTIAVFGSFLIGSGAEGAVVIFLFYIALYL
ENYAGERARKSIASLLKLVPETATLKKDGLTSEIHVHDVKAGDILVVKPGDKVPIDGKVIKGSTSINQAAITGESVPVNK
NIGDDIFAGTLNQEGYIEMDVTKESDQTVLSKIVKLVKESQKKRSNTENFIDKLAKYYTPAVIGLAALVAIIPVVFFGQS
IDEWVYRALVLLIISCPCAFLLSTPVAMVSGITASTKNGVLIKGSRYVEEMSKIKVMVFDKTGTLTQGNLELTDIIALNN
YSKAEILMVAGSLESNSNHPIGNAISSYVKGQGVKLSEVKDFKSITGNGLKGTLDNKTYILGKKNLFSNKYEFSDTMIRG
FEDQGKTVVLIANETEILGFICMKDTVRIASKSTISKLKNSGIKTVMLTGDNEQTAKTVADDIGLDEYYAELLPEDKVKI
IEKYIDKGIEVAMVGDGVNDAPALARSNVGIAMGAAGSDVAIETADIALMHDDISKINYLLNLSRKTMGVVKQNVSVALI
IQVSLSVLAVFGYVSLWMAVTFGDMGLTLAVILNSLRLVYTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-120 46
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-120 46
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-117 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Metbo_1239 YP_004290453.1 heavy metal translocating P-type ATPase BAC0298 Protein 2e-109 42