Gene Information

Name : LAC30SC_04810 (LAC30SC_04810)
Accession : YP_004292052.1
Strain : Lactobacillus acidophilus 30SC
Genome accession: NC_015214
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 977545 - 979314 bp
Length : 1770 bp
Strand : +
Note : COG0469 Pyruvate kinase

DNA sequence :
ATGAAGAAAACTAAGATTGTTAGTACTTTAGGGCCAGCTTCAAACGATATTGAAACTATTACCGCTTTAGCAAAAGCTGG
TGCAAACGTATTCCGTTTCAACTTCTCACACGGTGACCACCCAGAACACCTTGCTCGTATGAAGATGGTTCGTCAAGTGG
AAAAGGATACTGGTTTGCTTCTTGGTATCGACCTTGACACTAAGGGTGCTGAAATCAGAACCACTGAACAAGAAGGTGGC
AAGTTTACTATTAACACCGGTGACATGATCCGTGTATCAATGGATGCTACCAAGAAGGGTAACAAGGACATGATCCACGT
TACCTACGATGGTTTGTACGATGATACTCACGTTGGTGGTCACGTATTAATCGATGACGGTTTGGTTGACCTTTTGATCA
AGGAAAAGGACGACTCAAAGAGAGAATTAGTTTGTGAAGCTCAAAACACTGGTGTTATCGGTTCAAAGAAGGGTGTTAAC
GCTCCTGGCGTTGAAATCCGCCTCCCAGGTATCACTGAAAAGGATACTGACGACATCAAGTTCGGTTTGAAGTTCGGTAT
TAACTTCATTACTGCTTCATTTGCACGTAAAGCTCAAGATATCTTAGATATCCGTAAGCTTTGTGAAGAAGCAGGTGCAG
ACTACGTTAAGATCTTCCCTAAGATTGAATCACAAGAAGGTATTGACAACGCTGACGAAATCTTGCAAGTATCAGATGGT
TTGATGGTTGCTCGTGGTGACATGGGTGTTGAAATTCCATTCATGGAAGTTCCATTTGTACAAAAAAGCTTAATCCGTAA
GGCTAACGCACTTGGTAAGCCAGTTATCACTGCTACCCAAATGCTTGACTCAATGCAAGAAAACCCACGTCCAACTCGTG
CCGAAGTTTCAGACGTTGCTAACGCTGTTCTTGATGGTACTGACGCAACTATGCTTTCAGGTGAATCAGCAAACGGTCTT
TACCCAGTTAAGGCTGTTAAGGCTATGGCTGAAATTGACGAACGTACTGAAAAGCAAATGCTTAAGCGTAACACTTTAGC
ACTTCAAAGATTCGAAGCTTACAAGGGTTCAAACGTAACCGAAGCTATTGGTGAATCAGTTGTACGTACTGCTCAAGAAT
TAGGTGTTAAGACTATCATTACTGCAACTAATTCAGGTTACACTGCACGTATGATTTCTAAGTACCGTCCAAACGCAGAC
ATCATTGCATTGACCTTCGACGAAAAGATTCAACACTCATTAGGTATTGTTTGGGGCGTTCAACCAGTATTGACTGAAAA
GCCTAAGTCAACTGATGACATGTTTGAAGTAGCTGCTAAGGTAGCTAAGGAAAAGGGCTTTGTTAAGGATGGCGACCTTG
TAATCATCGTTGCCGGTGTTCCAGTTGGTGACTCAGGTACTACTAACTTGATGAAGTTACAAATCATCGGTGACAAGCTT
GTTCAAGGTTTAGGTGTTGGTAACGGTTCAGTTATCGGCAAGGCCGTTGTAGCAAACTCAGCAGAAGAAGCTAACAGCAA
GGTTAAGGAAGGCGACATCTTAGTTGCTAAGACTACTGACCCTGACTACAACCCAGCTATTAAGAAGGCTTCAGGCTTAG
TTGTTGAAGCTTCAGGTTTAACTTCACACGCAGCAGTTATCGGCTTATCATTAGGTATCCCAGTTGTTGTTGGTGCTACT
GACGCAACTTCAAAGATTTCTGATGGTTCAACTATTACTGTTGACGCTCGTCGTGGTGCTATCTACCAAGGCGAAATCTC
AAACCTTTAA

Protein sequence :
MKKTKIVSTLGPASNDIETITALAKAGANVFRFNFSHGDHPEHLARMKMVRQVEKDTGLLLGIDLDTKGAEIRTTEQEGG
KFTINTGDMIRVSMDATKKGNKDMIHVTYDGLYDDTHVGGHVLIDDGLVDLLIKEKDDSKRELVCEAQNTGVIGSKKGVN
APGVEIRLPGITEKDTDDIKFGLKFGINFITASFARKAQDILDIRKLCEEAGADYVKIFPKIESQEGIDNADEILQVSDG
LMVARGDMGVEIPFMEVPFVQKSLIRKANALGKPVITATQMLDSMQENPRPTRAEVSDVANAVLDGTDATMLSGESANGL
YPVKAVKAMAEIDERTEKQMLKRNTLALQRFEAYKGSNVTEAIGESVVRTAQELGVKTIITATNSGYTARMISKYRPNAD
IIALTFDEKIQHSLGIVWGVQPVLTEKPKSTDDMFEVAAKVAKEKGFVKDGDLVIIVAGVPVGDSGTTNLMKLQIIGDKL
VQGLGVGNGSVIGKAVVANSAEEANSKVKEGDILVAKTTDPDYNPAIKKASGLVVEASGLTSHAAVIGLSLGIPVVVGAT
DATSKISDGSTITVDARRGAIYQGEISNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-73 47
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-73 47
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-73 47
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-73 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LAC30SC_04810 YP_004292052.1 pyruvate kinase VFG0479 Protein 5e-74 47