Gene Information

Name : LAC30SC_00375 (LAC30SC_00375)
Accession : YP_004286406.1
Strain : Lactobacillus acidophilus 30SC
Genome accession: NC_015214
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 80121 - 80837 bp
Length : 717 bp
Strand : +
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence :
ATGCCAAAAAAAATTCTCGTCGTCGACGATGAAAAGCCTATATCTGATATTATCAAATTTAACCTAACTAAGGAGGGCTT
TGACGTCGACACTGCCTATGATGGCGAAGAAGCTGTTCAAAAAGTTGACGAATATGATCCAGATTTAATGATTCTGGACC
TGATGTTACCAAAGAAAGACGGACTCGAGGTTGCTCGTGAAGTTCGTCAAACGCACGATATGCCAATTATCATGGTAACT
GCTAAAGATACTGAAATTGATAAAGTTTTAGGACTTGAAATGGGTGCAGATGATTACGTAACTAAGCCATTTTCTAACCG
CGAATTAGTTGCTCGTGTTAAGGCTAACTTACGTCGCCGTGATATCGTTAAGAAGGCTGAGGCTGCTAACCAAGAAGAGC
CCGATAAGAATATTAAGATCGGCAATCTATTAATCATGCCAGATGCCTATATTGTTGAAAAGAATGGTAAGAAGATCGAA
CTTACTCACCGTGAATTTGAACTTCTTTACTACTTAGCACAACATATGGGACAAGTTATGACCCGTGAACACTTATTGCA
AACTGTTTGGGGCTATGATTATTTTGGTGATGTGCGGACTGTTGACGTAACCGTTCACCGTTTAAGAGAAAAGATTGAGA
ATAATCCAATTCAACCTCAAGTTTTAGTTACTCGCCGTGGTGTAGGTTATTACGTAAAACAGCCAAGTGAGGGATAG

Protein sequence :
MPKKILVVDDEKPISDIIKFNLTKEGFDVDTAYDGEEAVQKVDEYDPDLMILDLMLPKKDGLEVAREVRQTHDMPIIMVT
AKDTEIDKVLGLEMGADDYVTKPFSNRELVARVKANLRRRDIVKKAEAANQEEPDKNIKIGNLLIMPDAYIVEKNGKKIE
LTHREFELLYYLAQHMGQVMTREHLLQTVWGYDYFGDVRTVDVTVHRLREKIENNPIQPQVLVTRRGVGYYVKQPSEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 3e-31 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LAC30SC_00375 YP_004286406.1 response regulator NC_012469.1.7685629. Protein 1e-65 64
LAC30SC_00375 YP_004286406.1 response regulator NC_002952.2859905.p0 Protein 3e-50 53
LAC30SC_00375 YP_004286406.1 response regulator NC_002951.3237708.p0 Protein 4e-50 53
LAC30SC_00375 YP_004286406.1 response regulator NC_007622.3794472.p0 Protein 3e-50 53
LAC30SC_00375 YP_004286406.1 response regulator NC_002758.1121668.p0 Protein 4e-50 53
LAC30SC_00375 YP_004286406.1 response regulator NC_009641.5332272.p0 Protein 4e-50 53
LAC30SC_00375 YP_004286406.1 response regulator NC_013450.8614421.p0 Protein 4e-50 53
LAC30SC_00375 YP_004286406.1 response regulator NC_007793.3914279.p0 Protein 4e-50 53
LAC30SC_00375 YP_004286406.1 response regulator NC_003923.1003749.p0 Protein 3e-50 53
LAC30SC_00375 YP_004286406.1 response regulator NC_002745.1124361.p0 Protein 4e-50 53
LAC30SC_00375 YP_004286406.1 response regulator NC_009782.5559369.p0 Protein 4e-50 53
LAC30SC_00375 YP_004286406.1 response regulator HE999704.1.gene2815. Protein 3e-43 52
LAC30SC_00375 YP_004286406.1 response regulator NC_012469.1.7686381. Protein 2e-38 46
LAC30SC_00375 YP_004286406.1 response regulator AE016830.1.gene1681. Protein 3e-38 45
LAC30SC_00375 YP_004286406.1 response regulator AE000516.2.gene3505. Protein 2e-33 44
LAC30SC_00375 YP_004286406.1 response regulator CP001918.1.gene5135. Protein 1e-27 44
LAC30SC_00375 YP_004286406.1 response regulator CP001138.1.gene4273. Protein 7e-32 43
LAC30SC_00375 YP_004286406.1 response regulator BAC0533 Protein 4e-32 43
LAC30SC_00375 YP_004286406.1 response regulator NC_002695.1.915041.p Protein 3e-32 43
LAC30SC_00375 YP_004286406.1 response regulator CP000647.1.gene4257. Protein 4e-32 43
LAC30SC_00375 YP_004286406.1 response regulator CP000034.1.gene3834. Protein 3e-32 43
LAC30SC_00375 YP_004286406.1 response regulator FJ349556.1.orf0.gene Protein 2e-34 43
LAC30SC_00375 YP_004286406.1 response regulator AF155139.2.orf0.gene Protein 2e-34 43
LAC30SC_00375 YP_004286406.1 response regulator NC_002952.2859858.p0 Protein 4e-33 42
LAC30SC_00375 YP_004286406.1 response regulator NC_007622.3794948.p0 Protein 4e-33 42
LAC30SC_00375 YP_004286406.1 response regulator NC_003923.1003417.p0 Protein 4e-33 42
LAC30SC_00375 YP_004286406.1 response regulator NC_013450.8614146.p0 Protein 4e-33 42
LAC30SC_00375 YP_004286406.1 response regulator NC_002951.3238224.p0 Protein 4e-33 42
LAC30SC_00375 YP_004286406.1 response regulator NC_007793.3914065.p0 Protein 4e-33 42
LAC30SC_00375 YP_004286406.1 response regulator NC_002758.1121390.p0 Protein 4e-33 42
LAC30SC_00375 YP_004286406.1 response regulator NC_010079.5776364.p0 Protein 4e-33 42
LAC30SC_00375 YP_004286406.1 response regulator AE015929.1.gene1106. Protein 5e-27 42
LAC30SC_00375 YP_004286406.1 response regulator AF162694.1.orf4.gene Protein 6e-33 42
LAC30SC_00375 YP_004286406.1 response regulator CP004022.1.gene3215. Protein 3e-30 42
LAC30SC_00375 YP_004286406.1 response regulator NC_005054.2598277.p0 Protein 9e-33 41
LAC30SC_00375 YP_004286406.1 response regulator NC_014475.1.orf0.gen Protein 9e-33 41
LAC30SC_00375 YP_004286406.1 response regulator AM180355.1.gene1830. Protein 1e-33 41
LAC30SC_00375 YP_004286406.1 response regulator NC_011595.7057856.p0 Protein 3e-23 41
LAC30SC_00375 YP_004286406.1 response regulator NC_010410.6002989.p0 Protein 3e-23 41
LAC30SC_00375 YP_004286406.1 response regulator NC_010400.5986590.p0 Protein 1e-22 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LAC30SC_00375 YP_004286406.1 response regulator VFG1563 Protein 1e-31 42
LAC30SC_00375 YP_004286406.1 response regulator VFG1389 Protein 2e-28 41