Gene Information

Name : LAC30SC_03745 (LAC30SC_03745)
Accession : YP_004291857.1
Strain : Lactobacillus acidophilus 30SC
Genome accession: NC_015214
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 775537 - 776253 bp
Length : 717 bp
Strand : +
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
TTGAAAATATTAATGGTTGAAGATGACAATTCCGTCGCTGAAATGATGGGAATGTTTTTCAAAAAAGAAGGCTGGGAACA
AGATATTGCTGTCGACGGTGTCGAAGCCGTCGATATGTTTAAAGAAAATGCGGATAAGTATGATTTGATTACGCTAGACT
TGAATTTGCCTAAAAAAGACGGAATTCAAGTGGCCAAGGAAGTAAGAGCAATTTCTCCTACTGTTCCAATTATCATGCTT
ACTGCAAGAGGCAGTGAATCAGATCAAGTACTCGGTTTAGGTATCGGAGCCGACGAGTATGTCACTAAGCCTTTTAGTCC
AATTGCTTTAATTGCTAGAATTAAGGCTCTTCATCGTCGAGTAATGATGGAGGAAAAGCCTGCACTTCCGCAAGAAAAGA
AGCAAGACTATGATATTGAAACTGAGCACTTAAAGATTTCAAAGAGTAGACGTGAAGTCTTATTCGACGCTCAGCCTGTG
ACCGATTTAACACCTAAAGAATTTGACTTGCTTTATACGATGGCACAAAAGCCTAAGCAAGTCTTTTCGCGTGATCAGCT
TTTGGAATTGGTGTGGGGCTATGAATATTACGGTGAGGAAAGAACCGTAGATGCCCACATTAAGAAGTTGCGTCAAAAGC
TCGAAAAGGTTGGAGCTAAAGTGATCCAAACTGTTTGGGGCGTCGGTTATAAATTTGATGATTCACAGGCAAAATAA

Protein sequence : 
MKILMVEDDNSVAEMMGMFFKKEGWEQDIAVDGVEAVDMFKENADKYDLITLDLNLPKKDGIQVAKEVRAISPTVPIIML
TARGSESDQVLGLGIGADEYVTKPFSPIALIARIKALHRRVMMEEKPALPQEKKQDYDIETEHLKISKSRREVLFDAQPV
TDLTPKEFDLLYTMAQKPKQVFSRDQLLELVWGYEYYGEERTVDAHIKKLRQKLEKVGAKVIQTVWGVGYKFDDSQAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 2e-35 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 3e-35 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LAC30SC_03745 YP_004291857.1 response regulator HE999704.1.gene2815. Protein 2e-39 44
LAC30SC_03745 YP_004291857.1 response regulator FJ349556.1.orf0.gene Protein 8e-40 42
LAC30SC_03745 YP_004291857.1 response regulator NC_012469.1.7685629. Protein 1e-37 42
LAC30SC_03745 YP_004291857.1 response regulator NC_002952.2859905.p0 Protein 2e-38 42
LAC30SC_03745 YP_004291857.1 response regulator NC_009782.5559369.p0 Protein 1e-38 42
LAC30SC_03745 YP_004291857.1 response regulator NC_002951.3237708.p0 Protein 1e-38 42
LAC30SC_03745 YP_004291857.1 response regulator NC_007622.3794472.p0 Protein 2e-38 42
LAC30SC_03745 YP_004291857.1 response regulator NC_002758.1121668.p0 Protein 1e-38 42
LAC30SC_03745 YP_004291857.1 response regulator NC_009641.5332272.p0 Protein 1e-38 42
LAC30SC_03745 YP_004291857.1 response regulator NC_013450.8614421.p0 Protein 1e-38 42
LAC30SC_03745 YP_004291857.1 response regulator NC_007793.3914279.p0 Protein 1e-38 42
LAC30SC_03745 YP_004291857.1 response regulator NC_003923.1003749.p0 Protein 1e-38 42
LAC30SC_03745 YP_004291857.1 response regulator NC_002745.1124361.p0 Protein 1e-38 42
LAC30SC_03745 YP_004291857.1 response regulator CP001918.1.gene5135. Protein 1e-24 42
LAC30SC_03745 YP_004291857.1 response regulator AF155139.2.orf0.gene Protein 6e-40 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LAC30SC_03745 YP_004291857.1 response regulator VFG1563 Protein 1e-35 42
LAC30SC_03745 YP_004291857.1 response regulator VFG1702 Protein 1e-35 42