Gene Information

Name : guaA (LAC30SC_01170)
Accession : YP_004286563.1
Strain : Lactobacillus acidophilus 30SC
Genome accession: NC_015214
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 245350 - 246885 bp
Length : 1536 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
GTGGCTAAAAATCTAGACGATTTTGACAAGATTATTGTTCTTGACTTTGGTAGTCAATACAATCAATTAATCACTCGACG
CATTCGTGATTTTGGCATCTACTCAGAACTTTTGCCCCACGATCTTTCAATTGACAGGATCAAGGAAATGAATCCTAAAG
GAATTATTTTCTCAGGTGGTCCAAACAGTGTTTATGACGATGGTGCTTTGAAGGTTGATCCTGAAATCTTTAAATTAGGT
ATTCCTATTTTGGGTATTTGTTACGGGATGCAACTGATGAGCTATGACTTGGGCGGCAAGGTTGAACCTGCTGATAACAA
GGAATACGGTAGAGCAAACATTACTGTCGAAGATCCAGACAGTGCTTTATTCAAGGGCTTACCAAGCAAGCAATACGTTT
GGATGAGCCACGGTGACTTAGTAACCCAAGCACCTAAGGGCTTTGAAGTAACTGCTTCAAGCAAGAACTGTCCAATCGCT
GCAATTGATAACCCAGACAAAAAGTTCTACGGTATCCAATTCCACGCTGAAGTTCGTAACTCAGAATATGGTTTGGACAT
CTTGAAGCGTTTTGCCTTTGACGTTTGTGGTGCCGTAGCTAACTGGACTATGGATGACTTCATCGACATGAAGATTGGCG
AAATCCGTAAGGAAGTCGGTGACAAGAAGGTTATCTTAGGTCTTTCTGGTGGTGTTGACTCAAGTGTTACTGCCACTTTG
CTTCACAAGGCAATTGGTAATCAATTGACTGCTATTTTCGTTGATCACGGGATGCTTCGTAAGGACGAAGGCGACCAAGT
TATGAAGGCTTTGAACAAGGACCTCGGTGTTAACATTATCCGTGTTAACGCACAAAAGAGATTCTTGGACAAGCTTAAGG
GCGTAACTGATCCTGAAAAGAAGCGTAAGATCATCGGTAAGGAATTTATCGAAGTCTTCAACGAAGAAGCTAAAAAGATT
AAGGATGTTGACTTCTTAGCACAAGGTACTTTGTACACTGACGTCATTGAGTCAGGTACTAATACTGCTCAAACTATCAA
ATCACACCACAACGTAGGTGGTCTTCCTAAGGACATGCACTTTAAACTTATTGAACCACTTCGCAAGTTGTTCAAGGATG
AAGTTCGTGAACTTGGTGAAAAACTTGGTATTCCACATGACTTAGTATGGCGTCAACCATTCCCAGGTCCAGGTCTTGGT
ATTCGTGTTCTTGGCGAAGTTACTGAACCTAAGCTGAAGATCGTGCGTGAATCTGATGCGATTTTGCGTGACGAGATTAA
GAAAGCTGGATTGCAAGAAAAGATTTGGCAATACTTTACTGTTTTGCCAGGAATTCGTTCAGTTGGTGTGATGGGTGATG
GTCGTACTTATGACTACACCATTGGTATTCGTGCCGTAACTTCAATTGACGGTATGACTGCAGACTTTGCGAAAATTCCA
TGGGACGTACTTGGTCACATTTCAGATAGAATCGTTAACGAAGTAGATAACGTTAACCGTGTAGTTTACGATGTAACGAG
TAAGCCACTCTATTAA

Protein sequence :
MAKNLDDFDKIIVLDFGSQYNQLITRRIRDFGIYSELLPHDLSIDRIKEMNPKGIIFSGGPNSVYDDGALKVDPEIFKLG
IPILGICYGMQLMSYDLGGKVEPADNKEYGRANITVEDPDSALFKGLPSKQYVWMSHGDLVTQAPKGFEVTASSKNCPIA
AIDNPDKKFYGIQFHAEVRNSEYGLDILKRFAFDVCGAVANWTMDDFIDMKIGEIRKEVGDKKVILGLSGGVDSSVTATL
LHKAIGNQLTAIFVDHGMLRKDEGDQVMKALNKDLGVNIIRVNAQKRFLDKLKGVTDPEKKRKIIGKEFIEVFNEEAKKI
KDVDFLAQGTLYTDVIESGTNTAQTIKSHHNVGGLPKDMHFKLIEPLRKLFKDEVRELGEKLGIPHDLVWRQPFPGPGLG
IRVLGEVTEPKLKIVRESDAILRDEIKKAGLQEKIWQYFTVLPGIRSVGVMGDGRTYDYTIGIRAVTSIDGMTADFAKIP
WDVLGHISDRIVNEVDNVNRVVYDVTSKPLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-170 68
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-170 68
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-170 68
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-128 51