Gene Information

Name : LAC30SC_10320 (LAC30SC_10320)
Accession : YP_004293096.1
Strain : Lactobacillus acidophilus 30SC
Genome accession: NC_015214
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1996654 - 1998783 bp
Length : 2130 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGCATACTTTGACAATGATTTTGACAACTTATTTAACGAATTGAACAGCTCATTCTTTAATGACGACTTCGGCAAGAG
AAGTGGCAATGGAAATGGCAACTCAGGTTCAATTCCAATTAACTACTCAAGCAACATGGGAGCAACCCCACAAACTATTC
AACAAAATCCTCAAAATCCAAATGAAAAACCAATTGGTGAAGATTTAGTTGAAGAAGCAAAGAACAACAAATTCGACCCA
GTTATCGGTCGTGATGAACAAATCGATAACGTAATCGAAATTTTATCAAGACGTAAGAAGAACAATCCAGTTTTAATTGG
ACCTGCTGGTGTTGGTAAAACCTCTATCGTAGAAGGCTTGGCTGAAAGAATTGCTTCTGGCAACGTTCCAGCTAAGATGG
CAAACATGCACATTATTTCAGTAAATATTAACGACATGGTTGCTGGTTCAAGCCTTCGTGGTAGCTTTGAAGAGAGACTT
AAGAAAGTTATCGACAAAGCTAAGAGTGATCCTAACATTGTTTTATTCATCGACGAATTACACAACATTGTAGGTGCAGG
TTCTACTGATTCAGAAAACAACAACGGTGACGCTGCTAACATCTTGAAGCCAGCTCTTGCAAGCGGTGACTTGAAGTTAA
TCGGTGCTACTACTACAAGCGAATTCCAAAGAATTGAAAAAGACCCAGCATTATCACGTAGATTCCAAGCTGTACAAGTT
CCAGAACCTACTACTGATGTAGCTGTTAAGATTCTGGAAGGCTTGAAGAAGAAATACGAGGACTACCACCACGTAAAATA
CACTGACGACAGCCTTAAATTAGCCGTTGAATTATCAGAAAGATACATTCAAGGTCGTTACTTACCAGACAAGGCCATCG
ACTTGATGGATGAAGCTGGTGCTAAGAAGGCTTTGCTTGTACAACCAACTGATGAAAAGAGCTTGAAGAATCAAATCAAT
GCTCTTGAAGCTAAGAAGTCAGAAGCTGCTAAGGCTGAAGACTACGACAAGGCTTCAGAAATTAAGAACAAGATTGCTGA
CCTTGAAAAGCAACTTAAGAACGTAGACACTAAGAATACTCCAGAAGTAACTGAGAAAGACATCTACGAAATTATTGAGC
AAAAGACTAAAATTCCTATGAGCGAACTCCACGCTGACGAAGCTCAAAAGAACTTAGACCTTGCTAAGAAGTTAAAGCAA
AACGTTATTGACCAAGACAGAGCAATTGATGTAATTACTGACGCTATTGCTCGTAAGCAAATCTTTAAAGACAGCGATCG
TCCTACTGGTTCATTCTTACTTACTGGTCCTACTGGTGTTGGTAAGACTGAACTTGCTAAGCAATTAGCTATCCAATTAT
TTGGTAACAAAGACCACTTAATCCGTTTGGACATGAGTGAATACCAAGACGAGATGGCTGTTAACAAGTTAATCGGTTCA
GCTCCTGGTTACGTTGGCTACGGTGAAGGTGGTCAATTAACTGAAAAAGTTCGTCACCAACCATACTCATTGATTTTGTT
CGATGAAATTGAAAAGGCTAACCCACAAGTCTTCAACGCACTTCTCCAAATTATGGATGATGGTCGTTTGACTGACGCAC
AAGGCAGAACCGTTTCATTCAAAGACACTATCTTGATTATGACTTCAAACGCAGGCTTCTCAGACAAGCTTCTTGAAGAC
GGCAAGGTTGACCAAGACAAGTTAATCTCAGCTCTTGAAAACTACTTCAGACCTGAATTCTTGAACCGTTTGGACGCAAT
CGTTCCATTCAACTCACTTACTGAACAAGACATGGGCAAGATCATCAACATTTACTTGAAGAAGATGTCCCACGTACTTG
CTAAGAAGGGTGTAACTGTTGAAGTTTCAGACGAAGCTAAGGCATTCTTGGCAGAAAAGGGTTACGACAAGAAGTTCGGT
GCTCGTCCACTTAGAAGAGTTGTTGAACAAAACCTTGAAACTCCAGCTGCTAAGTTGATCTTAAGAGAACCTGACACTAA
GAAGGTTGAATTTACTGCTGACGACAAGCACTTGTACTTGAACGGCAAAGCAATCTTCGACATTTCTCCAAAGATTGAAG
AAAAGGTTAAGGAAGACGAAGCTAAGGCTGACGACAAGAAAGAAGACTAA

Protein sequence :
MAYFDNDFDNLFNELNSSFFNDDFGKRSGNGNGNSGSIPINYSSNMGATPQTIQQNPQNPNEKPIGEDLVEEAKNNKFDP
VIGRDEQIDNVIEILSRRKKNNPVLIGPAGVGKTSIVEGLAERIASGNVPAKMANMHIISVNINDMVAGSSLRGSFEERL
KKVIDKAKSDPNIVLFIDELHNIVGAGSTDSENNNGDAANILKPALASGDLKLIGATTTSEFQRIEKDPALSRRFQAVQV
PEPTTDVAVKILEGLKKKYEDYHHVKYTDDSLKLAVELSERYIQGRYLPDKAIDLMDEAGAKKALLVQPTDEKSLKNQIN
ALEAKKSEAAKAEDYDKASEIKNKIADLEKQLKNVDTKNTPEVTEKDIYEIIEQKTKIPMSELHADEAQKNLDLAKKLKQ
NVIDQDRAIDVITDAIARKQIFKDSDRPTGSFLLTGPTGVGKTELAKQLAIQLFGNKDHLIRLDMSEYQDEMAVNKLIGS
APGYVGYGEGGQLTEKVRHQPYSLILFDEIEKANPQVFNALLQIMDDGRLTDAQGRTVSFKDTILIMTSNAGFSDKLLED
GKVDQDKLISALENYFRPEFLNRLDAIVPFNSLTEQDMGKIINIYLKKMSHVLAKKGVTVEVSDEAKAFLAEKGYDKKFG
ARPLRRVVEQNLETPAAKLILREPDTKKVEFTADDKHLYLNGKAIFDISPKIEEKVKEDEAKADDKKED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-133 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LAC30SC_10320 YP_004293096.1 ATP-dependent Clp protease, ATP-binding subunit VFG0080 Protein 2e-149 51
LAC30SC_10320 YP_004293096.1 ATP-dependent Clp protease, ATP-binding subunit VFG0079 Protein 4e-133 45