Gene Information

Name : LAC30SC_10855 (LAC30SC_10855)
Accession : YP_004286328.1
Strain :
Genome accession: NC_015213
Putative virulence/resistance : Resistance
Product : erythromycin resistance protein
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0030
EC number : -
Position : 1346 - 2083 bp
Length : 738 bp
Strand : -
Note : COG0030 Dimethyladenosine transferase (rRNA methylation)

DNA sequence : 
ATGAACAAAAATATAAAATATTCTCAAAACTTTTTAACGAGTGAAAAAGTACTCAACCAAATAATAAAACAATTGAATTT
AAAAGAAACCGATACCGTTTACGAAATTGGAACAGGTAAAGGGCATTTAACGACGAAACTGGCTAAAATAAGTAAACAGG
TAACGTCTATTGAATTAGACAGTCATCTATTCAACTTATCGTCAGAAAAATTAAAACTGAATACTCGTGTCACTTTAATT
CACCAAGATATTCTACAGTTTCAATTCCCTAACAAACAGAGGTATAAAATTGTTGGGAGTATTCCTTACAATTTAAGCAC
ACAAATTATTAAAAAAGTGGTTTTTGAAAGCCATGCGTCTGACATCTATCTGATTGTTGAAGAAGGATTCTACAAGCGTA
CCTTGGATATTCACCGAACACTAGGGTTGCTCTTGCACACTCAAGTCTCGATTCAGCAATTGCTTAAGCTGCCAGCGGAA
TGCTTTCATCCTAAACCAAAAGTAAACAGTGTCTTAATAAAACTTACCCGCCATACCACAGATGTTCCAGATAAATATTG
GAAGCTATATACGTACTTTGTTTCAAAATGGGTCAATCGAGAATATCGTCAACTGTTTACTAAAAATCAGTTTCATCAAG
CAATGAAACACGCCAAAGTAAACAATTTAAGTACCGTTACTTATGAGCAAGTATTGTCTATTTTTAATAGTTATCTATTA
TTTAACGGGAGGAAATAA

Protein sequence : 
MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLI
HQDILQFQFPNKQRYKIVGSIPYNLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNNLSTVTYEQVLSIFNSYLL
FNGRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ermA NP_370576.1 rRNA methylase Not tested Type-II SCCmec Protein 5e-54 52
ermA NP_373288.1 rRNA methylase Not tested Type-II SCCmec Protein 5e-54 52
ermA-3 YP_190052.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 5e-54 52
unnamed BAB47663.1 rRNA adenine N-6-methyltransferase Not tested Type-III SCCmec Protein 1e-53 52
unnamed BAC53825.1 rRNA adenine N-6-methyltransferase Not tested SRImec-III and SCCmec-III region Protein 1e-53 52
ermA BAC57474.1 rRNA methylase Not tested Type-IIIinv SCCmec Protein 4e-54 52
ermA BAA82205.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 4e-54 52
ermA1 YP_039522.1 rRNA adenine N-6-methyltransferase 1 Not tested Type-II SCCmec Protein 5e-54 52
ermC NP_273130.1 rRNA adenine N-6-methyltransferase Not tested IHT-A Protein 3e-57 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein AM410044.gene14.p01 Protein 6e-112 99
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein AM903082.gene3.p01 Protein 6e-112 99
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein AM180355.1.gene2254. Protein 4e-110 98
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein AM180355.1.gene2259. Protein 4e-110 98
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein M15332.gene.p01 Protein 1e-53 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_002745.1125313.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein AJ313523.1.orf0.gene Protein 5e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_009782.5559087.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_002758.1121630.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_002952.2859615.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_002745.1123579.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_002745.1124852.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_009782.5559229.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_002758.1120012.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_002952.2859614.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_002745.1122822.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_002745.1124324.p0 Protein 2e-54 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein V01278.gene.p01 Protein 2e-58 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein M64090.gene.p01 Protein 3e-56 52
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_010685.6295744.p0 Protein 1e-57 51
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_010686.6295746.p0 Protein 1e-57 51
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_007209.3523503.p0 Protein 1e-57 50
LAC30SC_10855 YP_004286328.1 erythromycin resistance protein NC_007792.3912746.p0 Protein 5e-57 50