Gene Information

Name : merA (ACMV_26480)
Accession : YP_004284877.1
Strain : Acidiphilium multivorum AIU301
Genome accession: NC_015186
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 2908387 - 2909826 bp
Length : 1440 bp
Strand : -
Note : -

DNA sequence :
ATGGACGCTGTGACGACACATGATTGCTGCGCATCCTCCCGCGCCACGACCCCCGATCTGGTGGTGATCGGTGCTGGATC
GGCGGGGTTTTCCGCCGCGATCCGGGCGAGCGAACTCGGCGCGAACGTGGCCTTGATCGGTCATGGCACGATCGGTGGCA
CCTGCGTGAATATCGGTTGCGTGCCGTCGAAAACCCTGATCCGCGCGGCCGAGGCGTTGCATCATGCCAAATCTTCCAGC
CGCTTCGCCGGCATCGCGGGTGCTGCGCGGATCAATGATTGGTCGGCCCTGATGGCACAGAAGGACCAGCTCGTCGCCGA
TCTGCGCGGGGCCAAATACCAGGCGCTGCTCCCGGAATACGAGACCATCCGCTATGTTCAGGGCCGCGCGCGGTTTACCG
ATGCGGGGATTGAGGCGGGCGGTGCAATTTTCCCAGCCGATCGTGTGGTGATCGCCACCGGCGCCTCGGCCGCCGTGCCC
GCGATTCCCGGAATGGACGAGGTTCCCTATCTCACCAGCACCACAGCGCTCGCGCTGGACCGTTTGCCCAAATCCCTCCT
GATCATCGGCGGCGGGGTGATCGGCTGTGAACTGGGTCAGATGTTCGCACGGTTTGGCGTTGCCGTCACCATCGTCTGCC
GCTCGCGCTTGTTGCCGGGATTTGAGCCGGAGATCAGTGATGCACTTGCCGGCTATTTGCGTGACGAGGGCGTCACGATC
GAATGCGGCGTAACATATCGGCAAATCAGACAGACGGAAGCAGGTGTCGCACTCGACCTCTTGGCGGGTGAAACCGCCCA
GACCATCGAAGCTGAACAAGTTCTGATCGCCACCGGGCGGCGCGCGAACACAAGCGGTATGGGTCTAGGCACCGCCGGAA
TCGCGCTCGATCGGAACGGCGCGATCACGACCGATGAGCATCTCGCCACCAACCGGCCCGGAATCTATGCGGCGGGCGAT
GTTACCGGGCGGGACCAGTATGTCTACATGGCAGCCTATGGCGCGAAGCTCGCGACCGAGAATGCCCTGAATGGTGACAT
CCTCCGGTACGACTCGCGGGCGATGCCCGAGGTGGTGTTCACCGATCCGCAGGTTGCCAGCGTCGGCCTTACCGAGACCG
AAGCACGCCGTCAGGGCCAGGATATCCGCACCGTCAGGCTTGATCTTGTCCAGGTACCACGCGCGCTCGCGGCACGTGAT
ACACGTGGGCTGATCAAACTCGTCGCCGAGGCGGGCAGCCTGCGGCTGCTCGGCGCGCATATTCTGGCACCCGAGAGCGC
CGACAGCATCCAGACCGCCGTGCTCGCGATCAAGCATGACCTCACGGTCACCGATCTGGCGGATACATTGTTCCCGTATC
TGACCACGGTCGAGGGGCTGAAGCTCGCGTCGCTGGGATTCCAGAAGGATGTCGCCAAACTCTCCTGCTGCGCCGGATGA

Protein sequence :
MDAVTTHDCCASSRATTPDLVVIGAGSAGFSAAIRASELGANVALIGHGTIGGTCVNIGCVPSKTLIRAAEALHHAKSSS
RFAGIAGAARINDWSALMAQKDQLVADLRGAKYQALLPEYETIRYVQGRARFTDAGIEAGGAIFPADRVVIATGASAAVP
AIPGMDEVPYLTSTTALALDRLPKSLLIIGGGVIGCELGQMFARFGVAVTIVCRSRLLPGFEPEISDALAGYLRDEGVTI
ECGVTYRQIRQTEAGVALDLLAGETAQTIEAEQVLIATGRRANTSGMGLGTAGIALDRNGAITTDEHLATNRPGIYAAGD
VTGRDQYVYMAAYGAKLATENALNGDILRYDSRAMPEVVFTDPQVASVGLTETEARRQGQDIRTVRLDLVQVPRALAARD
TRGLIKLVAEAGSLRLLGAHILAPESADSIQTAVLAIKHDLTVTDLADTLFPYLTTVEGLKLASLGFQKDVAKLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-83 48
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-83 48
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-83 48
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 3e-79 48
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 3e-80 47
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 3e-80 47
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-93 46
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 1e-93 46
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 6e-81 46
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-80 46
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-80 46
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 3e-80 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_004284877.1 mercuric reductase BAC0652 Protein 1e-83 48
merA YP_004284877.1 mercuric reductase BAC0653 Protein 3e-82 47
merA YP_004284877.1 mercuric reductase BAC0224 Protein 6e-95 47
merA YP_004284877.1 mercuric reductase BAC0651 Protein 9e-94 46
merA YP_004284877.1 mercuric reductase BAC0650 Protein 1e-81 46
merA YP_004284877.1 mercuric reductase BAC0649 Protein 3e-71 41