Gene Information

Name : Dester_0817 (Dester_0817)
Accession : YP_004281517.1
Strain : Desulfurobacterium thermolithotrophum DSM 11699
Genome accession: NC_015185
Putative virulence/resistance : Virulence
Product : two component, sigma54 specific, transcriptional regulator, Fis family
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 823061 - 824434 bp
Length : 1374 bp
Strand : +
Note : COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789: IPR003593: IPR002078: IPR002197; KEGG: gsu:GSU1003 nitrogen regulation protein NR(I); PFAM: RNA polymerase sigma factor 54, interac

DNA sequence : 
ATGGCGAAGATTCTCATTGCTGATGATGAAAAGAGTATAAGAGTGGTTTTAAAAAAATACCTTTCTTCTTTAGGTCATGA
GGTTATTGAGGCCTCAGATGGAATTAAAGCTATAGAAGTTCTTAATAAAGAAAGTATAGACATTGCGTTTGTTGACATAA
GAATGCCAAAAAAAACAGGACTTGAGATACTTAAGGAAGTAAAGAATGTTCCAATCGTTATCTTAACTGCTTATGGCACT
ATGGATTATGCTATAAAAGCAATGGAAAACGGAGCAATAGAATACATTACAAAACCGTTTTCTTTTGAAGAAATAAAGTC
CATCCTAGATAAAGTGTTAAGTTTGCAGGAACGAGAAGAAGAAGAAGAAAGTTTTTGCGTAGAAGATGAGATTATTGGAA
CAAGCAGGAAAATGCAAGAAGTCTTTAAACTTATTGGTAGAGTTGCTAAAAGCAATGCAACGATACTCATAACGGGAGAA
AGCGGAACAGGAAAAGAACTTATTGCAAAAGCCATTCACAAATATTCTTCAAGAAGAGATAGACCTTTTTTAGCCGTAAA
TTGTGCAGCTCTTCCACCTAACCTTCTTGAGGCAGAGCTCTTTGGCTATGAAAAAGGTGCCTTTACAGGAGCAATATCAA
GTAAGAAAGGTATTTTTGAACAAGCAAATGGAGGGACTATTTTTCTTGATGAAATAGGAGAACTTGAACTTTCTCTTCAG
TCGAAACTCTTACGTGTTCTTCAGGAAAAAGAAATAAGAAGAATAGGAGGAACTAAAACTATCAAAGTTGACGTTAGAAT
TGTTACAGCAACAAATAGGAATCTCGAAGAAGAAGTAAAAAAGGGAAATTTTAGAGAAGACCTCTTTTTCCGTCTAAATG
TTGTAAATATAAACTTGCCTCCTCTAAGAGAAAGAAGAGAAGACATAATTCCTCTTGCTGTTTACTTTATAAAGAAGTTT
TCTAAGGAATTTAAGCTTCCTGTTAAAGAACTTTCTGAAAGTACCGTTGAGTGGCTTTTAAACTATGACTTTCCAGGAAA
TGTTAGAGAACTTGAAAATATGATTTTGAGAGCTATGCTTCTTTCTCCTATTGATATCATCGATGTAAAAGATTTAAAGC
CTACTGCTATTATCAGCAAAGAACCTGCATTTGAAGAAGCAATAAGGAATTTTGTGGTAGAAATTTTTACTGTTGAGCAA
AAGGAAAAGAATAACCTTTATGACCTTGTTATAAAAAGTGCTGAAAGGATTTTAATATCAGAAGTTTTAAAATACTGTAA
CTACAATCAAGTTAAAGCAGCTAAAATTCTTGGAATTCACAGGAATACTCTCAGAAAGAAAATAAAAGAACTAAAAATAG
AAATTTCTAATTAA

Protein sequence : 
MAKILIADDEKSIRVVLKKYLSSLGHEVIEASDGIKAIEVLNKESIDIAFVDIRMPKKTGLEILKEVKNVPIVILTAYGT
MDYAIKAMENGAIEYITKPFSFEEIKSILDKVLSLQEREEEEESFCVEDEIIGTSRKMQEVFKLIGRVAKSNATILITGE
SGTGKELIAKAIHKYSSRRDRPFLAVNCAALPPNLLEAELFGYEKGAFTGAISSKKGIFEQANGGTIFLDEIGELELSLQ
SKLLRVLQEKEIRRIGGTKTIKVDVRIVTATNRNLEEEVKKGNFREDLFFRLNVVNINLPPLRERREDIIPLAVYFIKKF
SKEFKLPVKELSESTVEWLLNYDFPGNVRELENMILRAMLLSPIDIIDVKDLKPTAIISKEPAFEEAIRNFVVEIFTVEQ
KEKNNLYDLVIKSAERILISEVLKYCNYNQVKAAKILGIHRNTLRKKIKELKIEISN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 5e-65 41
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 5e-65 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dester_0817 YP_004281517.1 two component, sigma54 specific, transcriptional regulator, Fis family BAC0089 Protein 7e-72 43
Dester_0817 YP_004281517.1 two component, sigma54 specific, transcriptional regulator, Fis family BAC0467 Protein 5e-74 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dester_0817 YP_004281517.1 two component, sigma54 specific, transcriptional regulator, Fis family VFG1214 Protein 3e-70 43
Dester_0817 YP_004281517.1 two component, sigma54 specific, transcriptional regulator, Fis family VFG1249 Protein 4e-69 43
Dester_0817 YP_004281517.1 two component, sigma54 specific, transcriptional regulator, Fis family VFG0116 Protein 2e-61 42