Gene Information

Name : Dester_0723 (Dester_0723)
Accession : YP_004281428.1
Strain : Desulfurobacterium thermolithotrophum DSM 11699
Genome accession: NC_015185
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 740977 - 741705 bp
Length : 729 bp
Strand : -
Note : COGs: COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; HAMAP: 3-deoxy-D-manno-octulosonate cytidylyltransferase; InterPro IPR004528: IPR003329; KEGG: coc:Coch_0027 3-deoxy-D-manno-octulosonatecytidylyltransferase; PFAM: Acylneuraminate cytidylyltran

DNA sequence :
GTGAAGAAGTTTCTTATTGCCATTCCTGCGAGAATAAAATCTAATAGACTTCCTGAAAAACCTTTAAGGCTTCTTTGTGG
TAAGCCATTAATTGCTTGGGTTGTAGAGTCATGTCTTAAGATTACAGAAAACGTTCTTGTTGCAACAGATGATTTAAGAG
TAAAGAAAATAGCTGAAAAATTTGGAGCTAAAGCTGTAATGACATCTCCTTCTCATCCAAGTGGTACAGATAGAATTTTT
GAAGCTGTTAAAGATCTTGAGTTTGAGTACATAGTAAATGTCCAGGGAGATGAACCCTTTGTGAAAGCAGACCATGTTTT
ACCCATCGTGGGAGCTCTCCAGAAAGGAGAAGAATACGCAACTATCGCGGTAAGATTTAACAATGAAGAAGAGATACTAA
ATCCAAACAATGTTAAAGTTGTAGTTGATAAACATAACCATGCAATCTATTTTTCAAGGAATGTAATTCCTTATCCTCGC
GATGGTAGAATTCAAATAGGTAACTACTTGAAACATATAGGAATTTATGGCTATACAAAAAATTCTTTACAAAAGTTTGT
CTCATGGAATGAGGGTTTTTTGGAAAGAATAGAGAAATTAGAACAGCTTAGAATTATAGAAAACGGAAAAAAGATTTATG
TATCTGTAGTTTCAGAAGGGTCTTTTGGAATAGATACAGAAGAAGATTTGAAAAAAGCTGCTGAAAAATTGGAAAGAGGA
GAGGTCTAA

Protein sequence :
MKKFLIAIPARIKSNRLPEKPLRLLCGKPLIAWVVESCLKITENVLVATDDLRVKKIAEKFGAKAVMTSPSHPSGTDRIF
EAVKDLEFEYIVNVQGDEPFVKADHVLPIVGALQKGEEYATIAVRFNNEEEILNPNNVKVVVDKHNHAIYFSRNVIPYPR
DGRIQIGNYLKHIGIYGYTKNSLQKFVSWNEGFLERIEKLEQLRIIENGKKIYVSVVSEGSFGIDTEEDLKKAAEKLERG
EV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-31 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-31 42