Gene Information

Name : Dester_0068 (Dester_0068)
Accession : YP_004280786.1
Strain : Desulfurobacterium thermolithotrophum DSM 11699
Genome accession: NC_015185
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 59739 - 61292 bp
Length : 1554 bp
Strand : -
Note : COGs: COG0519 GMP synthase PP-ATPase domain/subunit; HAMAP: GMP synthase [glutamine-hydrolyzing]; InterPro IPR000991: IPR001674: IPR004739; KEGG: pmx:PERMA_0029 GMP synthase; PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal;

DNA sequence :
ATGGTAAAGGATATACACGAAAGCAAAATACTTATACTTGATTTTGGTTCTCAGTACACTCAGCTTATTGCAAGGAGACT
AAGAGAAAAACATATCTACTGTGAAATTCATCCTTTTAACATTTCTATTGAAAAAATAAAAGAATTCAAACCAAAGGGAA
TAATACTTTCTGGAGGACCTGCAAGCGTTTATGCTCCAGATTCTCCAAAGATTAGCAAGGAAATTTTTGAGCTCGGTGTT
CCTGTCTTAGGAATATGCTACGGTATGCAGCTTATTACTTACCTTTTTGACGGAGAGGTTGTAAGAGCTGAAAGACACGA
ATACGGAAGAGCAGAACTTGAAATTTTAGATAGTTCCGATCTATTTGCCGAGCTCCCCGAAAAGTTTGTAGTTTGGATGA
GCCACGGAGATAGAGTTCTAAGAATTCCACCAACGTTTGAACCTATAGCCAAAACGGAAAACGCTCCTTATGCCGCTATA
AGAAACAAGGAAAAAAGGATCTTTGGTGTTCAATTTCATCCCGAAGTTAAGCACTCTCAATATGGAGACAAGGTCTTAGA
AAACTTTGCAGTCAAGATTTGCGGTTGTGAACCAAGTTGGACTATGGAAAACTTTATAGAATACGAAATTAAAAAGATAA
GAGAAATCGTAGGAGACAAAAACGTTATCTGTGCTCTTTCTGGAGGAGTTGATTCTTCTGTTGTTGCAGCACTTCTTCAC
AAAGCAATAGGAGATCAGCTTTACCCTATCTTTGTTGATACAGGACTTTTAAGAAAAGGTGAAAGAGAATCTGTAGAGAA
GACTTTCAGAGAAAAATTTCAGATGAAAAACTTTAGAACAGTTGATGCATCTTCTCTCTTTTTAGAAAGATTAAAAGGAG
TAACAGATCCTGAGAAGAAAAGAAAAATTATTGGACATACCTTCATAGAAGTTTTCGAAAAAGCTGCCAAGGAAATTCCA
AACGCTCACTTCTTAGCACAAGGAACACTTTATCCTGACGTTATAGAAAGTGTTTCAGTTAAAGGTCCATCTGCAACAAT
TAAGTCTCACCACAACGTTGGTGGGCTACCTGAAAGACTAAACTTTAAGCTTATAGAACCTTTGAGAGAACTTTTCAAAG
ATGAAGTAAGAGAACTTGGAAAGGAATTAGGTCTTCCTGAGGAAATAATTAAAAGACAGCCTTTCCCTGGACCTGGCCTT
GCTATTAGAATAGTTGGAGAAGTAAAACCTGAATACATAAAAATCTTGCGCGAAGCAGATGCAATAGTTCTTGAAGAAAT
AAAGAAAGCAGGACTTTACGACAAGATTTGGCAGTCTTTTGCAGTCTTTTTACCTGTACAGACTGTTGGAGTCATGGGAG
ACGTTAGAACTTACGATTACGTAATTGCTATAAGAGCAGTTGAAAGCGTCGATGGAATGACTGCTGACTGGGTTAAGTTA
CCTTACGAGCTTCTTGAAAGGATTTCAAACAGGATAATCAATGAAGTCGAAGGAGTAAACAGAGTAGTTTATGACATTAC
CTCAAAGCCACCAGGAACAATCGAGTGGGAGTAA

Protein sequence :
MVKDIHESKILILDFGSQYTQLIARRLREKHIYCEIHPFNISIEKIKEFKPKGIILSGGPASVYAPDSPKISKEIFELGV
PVLGICYGMQLITYLFDGEVVRAERHEYGRAELEILDSSDLFAELPEKFVVWMSHGDRVLRIPPTFEPIAKTENAPYAAI
RNKEKRIFGVQFHPEVKHSQYGDKVLENFAVKICGCEPSWTMENFIEYEIKKIREIVGDKNVICALSGGVDSSVVAALLH
KAIGDQLYPIFVDTGLLRKGERESVEKTFREKFQMKNFRTVDASSLFLERLKGVTDPEKKRKIIGHTFIEVFEKAAKEIP
NAHFLAQGTLYPDVIESVSVKGPSATIKSHHNVGGLPERLNFKLIEPLRELFKDEVRELGKELGLPEEIIKRQPFPGPGL
AIRIVGEVKPEYIKILREADAIVLEEIKKAGLYDKIWQSFAVFLPVQTVGVMGDVRTYDYVIAIRAVESVDGMTADWVKL
PYELLERISNRIINEVEGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-150 60
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-150 59
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-150 59
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-128 54