Gene Information

Name : kdsB (AGROH133_02950)
Accession : YP_004277408.1
Strain :
Genome accession: NC_015183
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 103764 - 104519 bp
Length : 756 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; CMP-2-keto-3-deoxyoctulosonic acid synthetase

DNA sequence : 
ATGAAGAATCGGGAATTCGAGAAAGCTGTCGTCCTTATACCGGCGCGGATGGCATCGACACGGCTTCCGGGCAAGCCTCT
CGCGGATATTGGCGGCAAACCGATGATTGTGCAGGTTGCACTCAGGGCGCGTGAAGCTGGCGCGACGCGAATCGTCGTTG
CAGTCGATGACGAACAGGTATTTTCAGCCGTAAAAAATGCCGGTTTCGACGTAATGATGACGCGCGATGATCACCAATCC
GGTTCGGACCGCATTTTCGAGGCGCTGCAGAAGGCCGACCCCTATGGCAACGCCGAATATGTCATCAATGTTCAGGGCGA
CCTTCCGACCATCGAAGCGGAAACGATCCGCGCCTCGTTGCGCCCGTTGGAAAATGCCGCCGTCGACATTGCCACGCTGA
CGGTGGAGATCACCGACGAGGAAGAAAAGACCAATCCGAACGTGGTGAAAGTGGTTGGCAGCCCGCTTTCCGAGACGCGA
TTGCGCGCGCTTTATTTTACCCGCGCGACTGCGCCCTATGGCGACGGACCTCTTTATCATCACATCGGCCTTTATACCTA
TCGCCGCGCCGCCCTTGAAACGTTCGTGAGGCTTCAGCCTTCGCCACTCGAGAAGCGCGAAAGGCTGGAACAATTGCGCG
CGCTGGAAGCGGGCATGCGTATTGATGCCGAAATCGTTCACTCCGTGCCGCTTGGCGTTGATACGCCGCACGATCTCGAA
AAAGCCCGCACTATTCTCGCAAACCGAACCCTCTGA

Protein sequence : 
MKNREFEKAVVLIPARMASTRLPGKPLADIGGKPMIVQVALRAREAGATRIVVAVDDEQVFSAVKNAGFDVMMTRDDHQS
GSDRIFEALQKADPYGNAEYVINVQGDLPTIEAETIRASLRPLENAAVDIATLTVEITDEEEKTNPNVVKVVGSPLSETR
LRALYFTRATAPYGDGPLYHHIGLYTYRRAALETFVRLQPSPLEKRERLEQLRALEAGMRIDAEIVHSVPLGVDTPHDLE
KARTILANRTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-34 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-34 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 8e-35 44