Gene Information

Name : guaA2 (AGROH133_03398)
Accession : YP_004277579.1
Strain :
Genome accession: NC_015183
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 271065 - 272642 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase, PP-ATPase domain/subunit

DNA sequence :
ATGACCCAGATAGCCCATCCCGACAGCATTCTCATCATCGATTTCGGCAGCCAGGTGACGCAGCTGATTGCGCGCCGCAT
CCGCGAAGCCGGGGTCTATTGCGAAATCCACCCGTTTCAGAATGCCGCAGAGGCGTTTGAGAAGCTCCAGCCCAAGGGCG
TGATCTTCTCCGGCGGCCCCGCATCTGTAACGGCGGAAGGCAGCCCGCGTGCGCCGCAGGCGGTGTTCGACAGCAAGGTT
CCGATCCTCGGCATCTGCTACGGCCAGCAGACGCTCTGCACCCAGCTTGGCGGCGTTGTCGAGGGCGGTCACGCGGCGGA
ATTCGGGCGCGCCGATATCGACATCAAAAAGGCAAGCCCTCTGTTCGACGGTTTCTGGGAACAGGGCAAGAGCTATCCCG
TCTGGATGAGCCACGGCGACCGCGTGACGAAACTGCCGGAGGGTTTCGAGGTTATCGCAACCTCTGAGAACGCACCCTTC
GCCATAGCTGCCGACGAGACACGCCATTATTACACCACCATGTTCCACCCGGAAGTGGTGCATACGCCAGATGGTGGCAA
GCTGCTCTCCAACTTCGTGCACAAGATCGTCGGTCTTAAATCCGATTGGACGATGGCAGCCTATCGCGCCGAGATGATCC
GCAAGATCCGCGATCAGGTCGGCACCGGGCGCGTGCTCTGCGCACTCTCCGGCGGCGTCGATTCCTCGGTTGCGGCGATC
CTCATCCATGAGGCGATCGGTGACCAGCTGACCTGCGTTTACGTTGATCATGGCCTGATGCGGCTTGGCGAAAGCGAGCA
GGTCGTCGGCATGTTCCGCGATCATTACAATATTCCGCTGGTACATGTGGATGCCGCAGACATGTTCCTGGGCCAGCTTT
CTGGCGTCTCCGACCCGGAAGTGAAGCGCAAGACTATCGGCCGTTTGTTCATCGAGGTCTTCGAGGCGGAAGCTGCCAAG
ATCGCAGCAGACGGCAAGGGTGCTCCGAATTTCCTCGCGCAGGGCACGCTTTACCCTGACGTCATCGAGAGCGTTTCTTT
CTCCGGCGGTCCTTCCGTCACCATCAAGAGCCACCACAATGTCGGTGGCCTTCCCGAGCGCATGAACATGCAACTGGTGG
AGCCGCTGCGCGAGCTCTTCAAGGACGAGGTGCGTGCGCTTGGCCGTGAACTCGGCCTGCCGGAAAGCTTCATCGGCCGC
CATCCCTTCCCCGGCCCGGGTCTGGCGATCCGTTGCCCCGGTGCGGTCACCCGCGAGAAGCTCGATATTCTGCGCAAGGC
AGATGCAATCTATCTCGACGAAATCCGCAAGGCGGGTCTTTACGACACCATATGGCAGGCCTTCGCAGTGCTGCTGCCGG
TGCAGACCGTGGGCGTCATGGGTGACTACCGCACCTATGACTTCGTCTGTGCGCTCCGCGCTGTGACGTCCGTGGATGGC
ATGACGGCGGATTTCTACCCCTACGACATGAATTTCCTCGGCCGCGCCGCGACCCGCATCATCAACGAAGTCCGCGGCAT
CAACCGTGTCGTCTATGACGTGACGAGCAAGCCGCCCGGCACGATCGAGTGGGAATAA

Protein sequence :
MTQIAHPDSILIIDFGSQVTQLIARRIREAGVYCEIHPFQNAAEAFEKLQPKGVIFSGGPASVTAEGSPRAPQAVFDSKV
PILGICYGQQTLCTQLGGVVEGGHAAEFGRADIDIKKASPLFDGFWEQGKSYPVWMSHGDRVTKLPEGFEVIATSENAPF
AIAADETRHYYTTMFHPEVVHTPDGGKLLSNFVHKIVGLKSDWTMAAYRAEMIRKIRDQVGTGRVLCALSGGVDSSVAAI
LIHEAIGDQLTCVYVDHGLMRLGESEQVVGMFRDHYNIPLVHVDAADMFLGQLSGVSDPEVKRKTIGRLFIEVFEAEAAK
IAADGKGAPNFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRALGRELGLPESFIGR
HPFPGPGLAIRCPGAVTREKLDILRKADAIYLDEIRKAGLYDTIWQAFAVLLPVQTVGVMGDYRTYDFVCALRAVTSVDG
MTADFYPYDMNFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-130 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-130 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-130 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-114 50