Gene Information

Name : Pedsa_1385 (Pedsa_1385)
Accession : YP_004273773.1
Strain : Pedobacter saltans DSM 12145
Genome accession: NC_015177
Putative virulence/resistance : Unknown
Product : hydroxymethylpyrimidine synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1634151 - 1636031 bp
Length : 1881 bp
Strand : -
Note : COGs: COG0422 Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: phe:Phep_2466 thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; SPTR: phosphomethylpyrimidine synthase; TIGRFAM: thiamine biosynthesis protein ThiC; PF

DNA sequence :
ATGGAAACAACAAAGAAGGATTTGGATTTGATATCAAGAGATCCATTTCCGGCATCAGAGAAAATCTATGTAAAAGGCAA
AATACACAACGTCAATGTGGCTATGCGGAGGATTTCCTTAAGCGATACCAAGATTCATAACGGATTTGGCTTAACTGAAA
AAAATGAAGCTGTAACAGTATATGACACAAGTGGACCCTATACGGATCCGAATATTCAGATTGATGTAAAGAAAGGGCTT
CCACGACTTAGGGAGCAATGGGTTTTGGATAGGAAAGACGTAAATCGTTTAGATGATATCAGTTCTGATTATGGGAAACT
ACGATTGAATGATGAAAAACTGGATCATTTACGTTTTGTGAGAAACGCCAATCCGTTAAAAGCCAAAACAGGCAATAACG
TAACTCAATTACATTATGCCCGAAAAGGAATTATTACTCCGGAAATGGAATATATCGCTATCCGCGAAAACCAGCAGATA
GAAATATTAAAAGATAGTTTGGGTGAGCGGTATGAAACCCTTGGGAAGCAGCATGAAGGAAATAGCTTTGGTGCATTAAC
ACCAAAAGGCTTTATTACACCCGAATTTGTAAGACAAGAGGTTGCAGCAGGTCGGGCAGTAATTCCCGCAAATATCAATC
ATCCGGAAGCAGAGCCTATGATTATAGGGCGCAATTTTTTGGTGAAAATCAACGCCAATATCGGAAATTCGGCGGTTACG
TCTTCAATTGAAGAAGAAGTAGAAAAAGCAGTGTGGGCATGCCGATGGGGAGCGGATACAATTATGGATTTGTCTACCGG
GAAAAATATCCATGAAACCCGTGAATGGATTATCAGGAATTCGCCAGTGCCTATTGGAACGGTTCCGATTTACCAGGCTC
TGGAAAAAGTGAATGGTAAAGCTGAGGACTTGACCTGGGAAATATTCAGAGATACGCTGATTGAGCAGGCTGAGCAAGGC
GTCGATTATTTTACCATCCATGCGGGAGTTTTGTTACGATATATTCCATTGACAGCTAAACGAATAACAGGTATTGTCTC
AAGAGGAGGTTCTATTATGGCAAAGTGGTGCCTGGCGCATCATAAAGAGAATTTTCTGTACACAAATTTCGAGGAGATAT
GCGAGATCATGAAAGCTTATGATGTTTCTTTCTCTCTGGGCGACGGGCTGAGACCCGGTTGTTTAGCTGATGCCAATGAT
GCTGCACAATTTGCTGAACTGGAAACTTTGGGAGGGTTAACTAAAATTGCATGGGAACATGACGTTCAAACAATTATAGA
AGGACCAGGGCATGTTCCTATGCACATGATTAAAGAGAATATGGAGAAGCAATTGCAATATTGTGAAGAAGCTCCTTTCT
ATACTTTAGGGCCATTAACCACGGATATCGCCCCCGGTTATGATCATATCACTTCGGCAATAGGTGCAGCGATGATTGGA
TGGTACGGAACTGCCATGTTGTGTTATGTGACTCCTAAAGAACATTTGGGGTTACCAAATAAAAAAGATGTTAAAGATGG
GGTGATTACCTATAAGATAGCTGCACATGCCGCAGATCTGGCTAAGGGACATCCAGGAGCACAATATAGAGATAATGCCT
TAAGTAAAGCTAGGTTTGAGTTTAGATGGGAAGATCAGTTTAACCTTTCTCTCGACCCCGACACAGCAAGGGAATTTCAC
GATGAGACTTTACCTGCAGATGGAGCTAAAATTGCCCATTTCTGTTCTATGTGCGGCCCAAATTTCTGCTCAATGAAAAT
AACACAGGATGTACGTACTTATGCAAAAGAGCAGGGGTTAGAAGACAACGAAGCCTTGGAAGCGGGAATGGCGGAGAAAT
CGGAGCAGTTTAAAGACAAGGGAAGCGAAATCTATTTGTAG

Protein sequence :
METTKKDLDLISRDPFPASEKIYVKGKIHNVNVAMRRISLSDTKIHNGFGLTEKNEAVTVYDTSGPYTDPNIQIDVKKGL
PRLREQWVLDRKDVNRLDDISSDYGKLRLNDEKLDHLRFVRNANPLKAKTGNNVTQLHYARKGIITPEMEYIAIRENQQI
EILKDSLGERYETLGKQHEGNSFGALTPKGFITPEFVRQEVAAGRAVIPANINHPEAEPMIIGRNFLVKINANIGNSAVT
SSIEEEVEKAVWACRWGADTIMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQG
VDYFTIHAGVLLRYIPLTAKRITGIVSRGGSIMAKWCLAHHKENFLYTNFEEICEIMKAYDVSFSLGDGLRPGCLADAND
AAQFAELETLGGLTKIAWEHDVQTIIEGPGHVPMHMIKENMEKQLQYCEEAPFYTLGPLTTDIAPGYDHITSAIGAAMIG
WYGTAMLCYVTPKEHLGLPNKKDVKDGVITYKIAAHAADLAKGHPGAQYRDNALSKARFEFRWEDQFNLSLDPDTAREFH
DETLPADGAKIAHFCSMCGPNFCSMKITQDVRTYAKEQGLEDNEALEAGMAEKSEQFKDKGSEIYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 74
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 74
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 71