Gene Information

Name : Plabr_4376 (Plabr_4376)
Accession : YP_004271971.1
Strain : Planctomyces brasiliensis DSM 5305
Genome accession: NC_015174
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 5433041 - 5434201 bp
Length : 1161 bp
Strand : -
Note : COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: plm:Plim_0611 cystathionine gamma-synthase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: cystathionine gamma-synthase; PFAM: Cys/Met me

DNA sequence :
ATGCTTGACGATCTTTCCAATCTGCATTTCTCCACTCGTGCGGTTCACGCTGGAGTTAACAAAGACACGCAATACAACAG
CTGCACCACGCCCATTTATCCCACGTCAACGTTCTACTGGGACGACCTGACGACCAACAGCGGTTACGACTACACCCGCA
GCGGCAACCCCACGCGGAAAGCGCTGGAAGAAAACATTGCCGCTCTCGAAGGGGGCGTGGGAGCTCAGGCGACCTGTACC
GGTATGTCAGCGATCAATGCGACGATGCATCTCTTCAGCCCGGGCGATCACATCATTGCCGGGAATGACATTTACGGCGG
CACCTACCGTCTGTTCTCCGACTTGTTCACGAAAATGGGACTGAAGTTCTCCTTCGTGCCGCAGGGCGACCTCGAAAAAG
TGAAGGATGCAATTCTTCCCGAAACGAAATGCATCTGGATTGAAACGCCGAGCAACCCGCTGCTCAATCTGGTCGACATT
GCCGCCATCACCGCAATCGCCAAAGAGCACAACCTGCTCACGATTGCCGACAACACGTTCCTGTCGCCTTACCTGCAGCG
TCCGTTCGAGTTTGGTGTCGATGTCGTTGTCCATTCGACGACCAAATACCTCAACGGTCATTCCGATGTCGTCGGCGGTT
GCGTGGTTTCGAGCACCGAAGAGTTGGCCCAGAAAGTGGCCTACATCGTCAACGGCCTCGGCCTGGGCTGTTCGCCTTTC
GATGCCTTCCTCGTGCTGCGTGGCGTGAAAACGCTCGGCCCGCGAATGGAAGCTCATCAAAAGGGAGCGATGGCGTTGGC
TCGCATGCTGGACGAACATCCAAATGTGGAGCGGGTCTATTACCCCGGTCTCGAATCGCACAAACAGCACGAGCTGGCCA
AAAAGCAGCAGTCTGGTTTCGGCGGGATGGTCAGCTTCGATATCAAAGGGGGCCGGCCGGCTGCCGAGAAACTGTTCGCC
AATATCAACCTGTTCCAGCTGGCGGAATCACTCGGCGGGATTGAGTCGCTGATTGAATATCCGGAAACGATGAGCCACGC
CTCAATGACGGCTGAAGCCCGGATGCATGGCGGCATCAGCGAAAGCACGATTCGTATTTCCGTCGGCATCGAAGATCCAG
CCGATCTGGTTGCCGATATGAAGCAGGCTCTCGAAGCGTAA

Protein sequence :
MLDDLSNLHFSTRAVHAGVNKDTQYNSCTTPIYPTSTFYWDDLTTNSGYDYTRSGNPTRKALEENIAALEGGVGAQATCT
GMSAINATMHLFSPGDHIIAGNDIYGGTYRLFSDLFTKMGLKFSFVPQGDLEKVKDAILPETKCIWIETPSNPLLNLVDI
AAITAIAKEHNLLTIADNTFLSPYLQRPFEFGVDVVVHSTTKYLNGHSDVVGGCVVSSTEELAQKVAYIVNGLGLGCSPF
DAFLVLRGVKTLGPRMEAHQKGAMALARMLDEHPNVERVYYPGLESHKQHELAKKQQSGFGGMVSFDIKGGRPAAEKLFA
NINLFQLAESLGGIESLIEYPETMSHASMTAEARMHGGISESTIRISVGIEDPADLVADMKQALEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-82 46
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-81 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-55 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Plabr_4376 YP_004271971.1 cystathionine gamma-synthase BAC0207 Protein 4e-62 42