Gene Information

Name : Plabr_2460 (Plabr_2460)
Accession : YP_004270083.1
Strain : Planctomyces brasiliensis DSM 5305
Genome accession: NC_015174
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 2939008 - 2940336 bp
Length : 1329 bp
Strand : +
Note : COGs: COG1157 flagellar biosynthesis/type III secretory pathway ATPase; InterPro IPR005714: IPR003593: IPR004100: IPR000194; KEGG: plm:Plim_3098 ATPase, FliI/YscN family; PFAM: ATPase, F1/V1/A1 complex, alpha/subunit beta, nucleotide-binding domain; ATPas

DNA sequence :
ATGTCTACAGCAACCAGTGCACTCCTGCGACAGATTGAGTCGATCGTCCCCTACGGGATGACCGGACAGGTTTCGCGCGT
TGTCGGCATGACCGCGCATGTGCGTGGCCTGGCTGCTCCGTTGGGAGCGGTTTGTCGAATCGAAGCAGGGCAGCGGCAGG
GAATTGATGCCGAAGTGATTGGTCTGGAAGACGACGAGATCATCCTTCAGCCCTACGGCGAACTGGCTGGCATTAAACGC
GGCGATACCGTTCGCCTGGTGCATTCCGCACAGCGAATTCGCGTCGGAGATCGACTGCTTGGACGTGTGATCAATGCTCG
CGGGGAGTTCATCGATGGTGATTTGCCTCCCGTTCTGCCCGAATCGTTGATGCTGCAGAACGCCCCGATCGCACCTCTGC
AACGCCCTCGGATTACCGAGCGGTTGGAAACCGGCGTGCGGGCAATCGACAGTCTGCTCACCTGCGGCCAGGGCCAACGA
CTCGGCATTTTCGCTGGCAGCGGTGTCGGAAAAAGCACCTTGCTCGGTCAGTTGGCGCGGTACGCCTCGGCCGATGTGAA
TGTGGTTGTGCTCGTTGGCGAAAGGGGCAGGGAGGTTCGCGAGTTTCTGGAACGCGACCTCGGCGAAGAAGGCCGCCGCC
GGAGTGTGCTCGTGGTCGCCACCAGTGAAGAATCAGCCCTGCTGCGTCGACAGTGTGCGAATGTCGGAACAGCTGTCGCC
GAATACTTTCGCGATCAGGGCAAGAATGTTCTGTTGATGATGGACAGTGTGACCCGTTATGCGCTCGCACAACGTGAAAT
TGGGCTGGCTGCCGGCGAACCGCCAGCCACACGCGGGTATCCCCCGAGTGTGTTTGCGTTGTTGCCCCGTCTTCTGGAAC
GCAGTGGTCGAACAGAGCGTGGCAGCATCACCGGGTTGTATACCGTTCTTGTCGAAGGGGATGATACCAACGAGCCAATC
GCCGACACCGTTCGCGGAATTCTCGACGGGCACATCGTGCTGTCTCGCGATCTGGCTCATAAAGCGCACTGGCCAGCCAT
TGATATTCTGGGCAGCATCAGCCGTTTGATGAACGAGCTGGCGGACGAAACGCACCTTGCTGCTGCCCGTCAATTGAAGC
AGCTGATGGCAGCGTATCGACAATCAGAAGACTTGATCAACATCGGGGCGTATCAGCATGGCTCCAATCGCGTGGTCGAT
CGCGCCATTCAGTTGAAGCCACGTATCGATGAATTTCTGCAGCAAACGTCCACCTCGCACACGCCGCTGCCCGAGACGAT
TCGGCTACTGCAACAGCTGACTGCCGGTATCGACGTAAACGCCAGGTAA

Protein sequence :
MSTATSALLRQIESIVPYGMTGQVSRVVGMTAHVRGLAAPLGAVCRIEAGQRQGIDAEVIGLEDDEIILQPYGELAGIKR
GDTVRLVHSAQRIRVGDRLLGRVINARGEFIDGDLPPVLPESLMLQNAPIAPLQRPRITERLETGVRAIDSLLTCGQGQR
LGIFAGSGVGKSTLLGQLARYASADVNVVVLVGERGREVREFLERDLGEEGRRRSVLVVATSEESALLRRQCANVGTAVA
EYFRDQGKNVLLMMDSVTRYALAQREIGLAAGEPPATRGYPPSVFALLPRLLERSGRTERGSITGLYTVLVEGDDTNEPI
ADTVRGILDGHIVLSRDLAHKAHWPAIDILGSISRLMNELADETHLAAARQLKQLMAAYRQSEDLINIGAYQHGSNRVVD
RAIQLKPRIDEFLQQTSTSHTPLPETIRLLQQLTAGIDVNAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-78 53
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-73 51
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-73 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-73 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-73 50
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-65 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-65 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-65 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-65 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-65 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-74 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-74 49
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-73 49
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-73 49
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-73 49
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-73 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-63 48
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-64 48
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-64 48
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-67 48
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-67 48
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-67 48
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-58 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 9e-64 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-73 47
escN AAL57542.1 EscN Virulence LEE Protein 5e-74 47
escN AAC38383.1 EscN Virulence LEE Protein 4e-74 47
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-74 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 7e-74 47
escN AAC31513.1 L0034 Virulence LEE Protein 5e-74 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 7e-74 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 5e-74 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 6e-74 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-74 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 5e-74 47
escN AAK26715.1 EscN Virulence LEE Protein 5e-74 47
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 8e-70 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 8e-70 46
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-72 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 7e-59 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 7e-59 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-68 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 7e-71 45
invC AAS66861.1 InvC Not tested SSR-2 Protein 3e-57 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-58 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-58 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-58 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-58 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 5e-60 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 5e-77 52
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 2e-79 51
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 5e-77 50
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 2e-77 50
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 2e-74 50
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 1e-65 50
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 1e-77 49
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 7e-76 48
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 2e-74 47
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 3e-74 47
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG2459 Protein 3e-62 46
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG1008 Protein 1e-57 44
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG0555 Protein 7e-59 42
Plabr_2460 YP_004270083.1 type III secretion system ATPase, FliI/YscN VFG1778 Protein 2e-58 42