Gene Information

Name : Sgly_3345 (Sgly_3345)
Accession : YP_004267608.1
Strain : Syntrophobotulus glycolicus DSM 8271
Genome accession: NC_015172
Putative virulence/resistance : Unknown
Product : primary replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 3385511 - 3386836 bp
Length : 1326 bp
Strand : -
Note : COGs: COG0305 Replicative DNA helicase; InterPro IPR007693: IPR007694: IPR003593: IPR007692; KEGG: dhd:Dhaf_4929 replicative DNA helicase; PFAM: DNA helicase, DnaB-like, C-terminal; DNA helicase, DnaB-like, N-terminal; SMART: ATPase, AAA+ type, core; SPTR

DNA sequence :
ATGGAACCAACAAAAGTTCCGCCACATAATTTAGAAGCTGAACAGGCAGTTTTGGGCTCCCTGATGCTTGATCCGGAACA
GGCCAGTGTGGCTTTTGAAATTTTGCGGTTTGAGGATTTTTACAGGGACAGCCACAAGATTATTTTCACCGCCATTCAAG
AGATACTGGACAAAGGCGAGCCTGTGGACTTGGTTACGGTCGCCGAATATCTTAGACAATATGGCCGTCTGGAGTCCATA
GGAGGAATCGGAACGATTTCCCAGGTCGCTTCCTCTGTTCCTTCCGCTGCCAATATCGAATATTATGCCAGGATCGTTGC
GGAAAAAGCGTTACTTCGCCAGCTGATCAAAATGGCTGGTTATCTGGAGCAGAAAGGGTATGAACCGGGCGAGGAGGCTT
TTGACCTTCTGGAAGAAGCCGAAAAGATGATTTTGGAGATCTCGCACAGGCAGACCAAGGACGGATTTATTTCCATCCAT
CATATTTTGCTGAAGACCTTTGAAAAGATAGAACACCTTTATACCAATAAAGGCAACCTGACCGGAGTCCCCACTCATTT
TAAGGAATTGGACAGACTAACCTCAGGCTGGCAGGCTTCCGATCTGGTTGTTATTGCGGGCAGGCCTTCCATGGGAAAAA
CCGCACTTGTGTTAAATATGGCCCAGAATGCTGCGGTTAAGTCTAAAGTAGCGGTGGCATTGTTTAGTCTGGAAATGTCT
AAAGAGCAGCTGGTTCAGCGGATGCTCTGTTCAGAAGCCATGGTTGACCAGCAGAGAGTACGAACCGGGGAATTGCTGGA
CAGTGACTGGCCTAAACTCACCCAGGCAGTCGGACCCCTTTCCAATGCGCCTATTTTTATTGACGATACGGTAGGAATCA
CTTTAGCGCAGCTGCGCTCCAAAGCCCGCCGCCTCAAAATGGAGCAGGGGTTAGGCTTGATTATTATTGATTATTTGCAA
TTAATGACCTTAGGGCGCCGGGCGGAAAGCCGTCAGCAGGAAGTGGCCCAGATCTCCCGTGGACTGAAAGGACTGGCCCG
TGAGCTGTCCGTGCCTGTTGTGGCATTGTCTCAGTTAAATCGCGGTGTGGAACAACGTCAGGATAAAAGGCCGGTTATGT
CCGATCTTTTGGAATCAGGGGCAATTGAAGCTGATGCGGATGTAATTTCTTTTATTTACCGGGATGAATATTATAATCCT
GAGTCAGAGAAAAAAGGGATAGCGGAAGTGATTATTGCCAAACACCGTAATGGTCCTGTTGGCACAGTTGAGCTGGGGTT
TCTGAAAGAGTTTACGAAGTTTGTTAATCTGGACAGGACACACTAA

Protein sequence :
MEPTKVPPHNLEAEQAVLGSLMLDPEQASVAFEILRFEDFYRDSHKIIFTAIQEILDKGEPVDLVTVAEYLRQYGRLESI
GGIGTISQVASSVPSAANIEYYARIVAEKALLRQLIKMAGYLEQKGYEPGEEAFDLLEEAEKMILEISHRQTKDGFISIH
HILLKTFEKIEHLYTNKGNLTGVPTHFKELDRLTSGWQASDLVVIAGRPSMGKTALVLNMAQNAAVKSKVAVALFSLEMS
KEQLVQRMLCSEAMVDQQRVRTGELLDSDWPKLTQAVGPLSNAPIFIDDTVGITLAQLRSKARRLKMEQGLGLIIIDYLQ
LMTLGRRAESRQQEVAQISRGLKGLARELSVPVVALSQLNRGVEQRQDKRPVMSDLLESGAIEADADVISFIYRDEYYNP
ESEKKGIAEVIIAKHRNGPVGTVELGFLKEFTKFVNLDRTH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 2e-80 44
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 8e-76 43
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 7e-67 43
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 3e-71 42
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 3e-75 42
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 1e-66 42
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 1e-66 42
dnaB1 YP_005176258.1 replicative DNA helicase Not tested ICEPmu1 Protein 2e-59 41