Gene Information

Name : Sgly_2784 (Sgly_2784)
Accession : YP_004267056.1
Strain : Syntrophobotulus glycolicus DSM 8271
Genome accession: NC_015172
Putative virulence/resistance : Resistance
Product : cysteine synthase; cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.47
Position : 2815591 - 2816814 bp
Length : 1224 bp
Strand : +
Note : COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: dsy:DSY3983 hypothetical protein; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: uncharacterized protein; PFAM: Cys/Met metabolism PLP-de

DNA sequence :
ATGATCCTAGAGATGAGATTGATCAGCCTCTTTCTTTCTAGGAAGAGGCTTTATTATTTCTTTGGCGGAGGGATTGAAAT
CGTGAAAGAGCAAAACATATTAACCAAACTCGCCCAAATCGGCAACAGACTTGATCCGACTGGCGCGATCAGTTTCCCGG
TCTATCATTCGTCAACTTTTGCCCATCCTGAACTGGGGAAAAGCACAGGCTACGATTATTCCCGTTCTGCAAATCCTACC
CGTAAGGTTTTGGAAGATTCTCTTGCCGCCCTGGAAGGCGGATGTAAGGGCTTTGCCTTTTCTTCTGGTTTAGCGGCAAT
TACAACAATCCTGTCGCTTTTTAAAAGCGGTGACCATTTCATTGTGACTGAAGATCTATATGGAGGGACTTATCGCCTTT
TTCAGCAGGTTTTTAACGAATTCGGCATTGAGGCCACTTTTGTCGATACAACGAGACCGGATCAAATAGAAGCCTCCATC
TGTCCAAATACCAAAGCTGTCTTTTGTGAGACCCCAAGCAATCCTCTGATGAAAGTGGCCGATATCCGGCAAATCTGCCG
GCTTGCCCAGTCTCATCACTTGTTGACCATAGTGGACAATACTTTTTTATCCCCGTATTTACAAAGGCCCTTGCAGCTTG
GGGCCGATATCGTCGTTCACAGTGCAAGCAAGTTTATCGGCGGGCACAATGACGTTATTGCGGGACTCGTGGCAGCCAGA
GAGGAACATTTAGCTGAACGTCTGGGTTTTTTGCAGAATGCTCTCGGCGCCGTTTTGGGACCTCAGGATTCCTGGCTGTT
GATTCGCGGTCTCAAAACCTTAGGGCTTCGTCTGGAATGCCAGCAGAGCAATGCACTCCGCATTGCTCACTGGCTGGAGA
ATCATCCCCTCGTTGATCAGGTTTTTTATCCCGGTCTTTCTGCCCATCCCGGTTATGACCTGCAATTAAGCCAGTCTTCC
GGTTTTGGGGCCATATTGTCTTTTTCCCTGAAAGATCACTGCTCGATCCCGGACATTCTTCAGAAATTCAAAGTGATATC
CTTTGCTGAAAGCCTGGGCGGAGTTGAAAGTCTGATCACTTATCCTTATATTCAGACTCATGCCGATATTCCCGAAGAGG
TGCGCAAACGTCTGGGCTTAAATGAATATTTATTGCGCATATCCGTAGGAATTGAAGACTGTAATGATCTGATCGACGAT
CTGAACCAGGCTTTAACCTTCTGA

Protein sequence :
MILEMRLISLFLSRKRLYYFFGGGIEIVKEQNILTKLAQIGNRLDPTGAISFPVYHSSTFAHPELGKSTGYDYSRSANPT
RKVLEDSLAALEGGCKGFAFSSGLAAITTILSLFKSGDHFIVTEDLYGGTYRLFQQVFNEFGIEATFVDTTRPDQIEASI
CPNTKAVFCETPSNPLMKVADIRQICRLAQSHHLLTIVDNTFLSPYLQRPLQLGADIVVHSASKFIGGHNDVIAGLVAAR
EEHLAERLGFLQNALGAVLGPQDSWLLIRGLKTLGLRLECQQSNALRIAHWLENHPLVDQVFYPGLSAHPGYDLQLSQSS
GFGAILSFSLKDHCSIPDILQKFKVISFAESLGGVESLITYPYIQTHADIPEEVRKRLGLNEYLLRISVGIEDCNDLIDD
LNQALTF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-93 50
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-92 50
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-65 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sgly_2784 YP_004267056.1 cysteine synthase; cystathionine gamma-synthase BAC0207 Protein 2e-58 41