Gene Information

Name : Sgly_1777 (Sgly_1777)
Accession : YP_004266075.1
Strain : Syntrophobotulus glycolicus DSM 8271
Genome accession: NC_015172
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1802187 - 1803914 bp
Length : 1728 bp
Strand : -
Note : COGs: COG0469 pyruvate kinase; InterPro IPR001697: IPR015793: IPR015794: IPR008279; KEGG: dhd:Dhaf_2755 pyruvate kinase; PFAM: pyruvate kinase, barrel; pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile domain; PRIAM: pyruvate kinase., pyruvate, wa

DNA sequence :
ATGCGGAGAACAAAGATTATATGCACAATAGGTCCTGCCAGTGAATCACCGGAAATGGTCCAAAAACTCTTATCCGCCGG
GATGAACGTGGCCAGGCTGAACTTCTCGCATGGTACACATGAAGAGCACGGTCGGAGAATCAAGGTTCTCAAGGAAGAAG
CAGCCAAAGCAGGCGTTAGTCTTGCGATCCTCCTGGATACCAAAGGACCGGAAATCAGAACCGGAATCGTTCCTGAAAAA
GGTATTGAGCTGGTCAAGGGAGCCAAATTTATCCTGGATACTTCCCGGGAGTTGGGTTCTTCTGAAAGGGTATCGATCAG
CTATGCCAGCCTCTGGCAGGAAGTAAAAACCGGAACACATATCCTGGTTGATGACGGCCTGATTGATTTGGAAGTTATCC
ATATTGCGGAAGAAAAAATCGAAACCAGAGTCTGCAATGGCGGTTTTTTGAAATCCCAAAAAGGGGTTAACGCTCCCGGA
GTAAACGTGCAGCTGCCTGCTCTCACGTCTAAAGATGTCGAAGATATTATCTTTGGTTTGGCAAATGAAATCGACTTCAT
TGCCGCTTCCTTTGCCAGGAAAGCCACCGATATCCTGGAAGTCCGGAGAATCGTAGAGGAAGCAGGGGCAAACGTAAGGA
TTATTGCTAAAATCGAAAACAGGGAAGGCTTAAATAACCTTGAAGAAATCCTTGAGGTCTCTGACGGCATCATGATCGCC
AGAGGAGATTTAGGTGTAGAGATCCCCGTAGAAGAAGTTCCCATTCACCAAAAAAATATTATTGCCCTTTGTAATGAGAT
CGGCAAACCGGTTGTCGTCGCTACCCAGATGCTGGATTCTATGATCAGACAGCCAAGACCAACCAGAGCGGAAGCTAGCG
ATGTGGCCAATGCGATTCTGGACGGTGCCGATGGGATCATGCTTTCGGGGGAAACGGCAGCCGGAAGTTATCCTTTAGAA
GCGGTAAAGACGATGGATAAGATCGCTAAACAAACGGAGCAAATTCTTTTCAAAAGCAACAATACCACATTTAAAATCCA
AAATATCGCCGAAGGAATAGGGCATGCCAGCAATACCATTGCAACAGATTTAAATGCCACAGCAATCATTACTCCGACCC
ATTCCGGCATTACCCCCCGGATGATTTCCCGTTTCAGGCCCAAGGCTCTGATTATTGCGGCTACTCCTTTTGAAGCAACA
GCCAGGAGTCTTGCCTTAAATTGGGGAGTGCACACCATGCTTGTTCCAATCAGTCATGAAACTGATGAGCTGCTGACGAT
TGCCGTAACAGGCGCTTTAACCCGTGACTTGGTCAAAGCAGGCGATATTGTTGTCCTGACAGCCGGAGTACCGGTTGGAA
AAACAGGCACCACAAATATGATCAAAGTTCAGGTTGTCGGAAATGTTTTAGCCAGAGGGACCGGTATCGGCAAAAGATTG
CTTTCAGGTACGGCCCGTACACAACAGGATATTGAACAGTTTAATCAGGGCGATATTCTGATTGCTTCTTATACCGATTC
TGAGGTCAATCCCTTTTTAGCCAAAGCGGGAGCCCTGGTCGTGGAAGAAGGCGGATTGACTTCTTACGCCGCCATCGCGG
CTTTGCAGTATGGGATCCCGGCCATTGTAGGTGCTGAGAACGCCCTGTCAAAGATCCGCGAAGGCCAGTCGATTACTGTT
GACGCTTATGCCGGTGTTGTCTATGAAGGGATCGTCAATATCATCTGA

Protein sequence :
MRRTKIICTIGPASESPEMVQKLLSAGMNVARLNFSHGTHEEHGRRIKVLKEEAAKAGVSLAILLDTKGPEIRTGIVPEK
GIELVKGAKFILDTSRELGSSERVSISYASLWQEVKTGTHILVDDGLIDLEVIHIAEEKIETRVCNGGFLKSQKGVNAPG
VNVQLPALTSKDVEDIIFGLANEIDFIAASFARKATDILEVRRIVEEAGANVRIIAKIENREGLNNLEEILEVSDGIMIA
RGDLGVEIPVEEVPIHQKNIIALCNEIGKPVVVATQMLDSMIRQPRPTRAEASDVANAILDGADGIMLSGETAAGSYPLE
AVKTMDKIAKQTEQILFKSNNTTFKIQNIAEGIGHASNTIATDLNATAIITPTHSGITPRMISRFRPKALIIAATPFEAT
ARSLALNWGVHTMLVPISHETDELLTIAVTGALTRDLVKAGDIVVLTAGVPVGKTGTTNMIKVQVVGNVLARGTGIGKRL
LSGTARTQQDIEQFNQGDILIASYTDSEVNPFLAKAGALVVEEGGLTSYAAIAALQYGIPAIVGAENALSKIREGQSITV
DAYAGVVYEGIVNII

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-99 48
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-99 48
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-99 48
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-99 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sgly_1777 YP_004266075.1 pyruvate kinase VFG0479 Protein 1e-99 48