Gene Information

Name : Sgly_0135 (Sgly_0135)
Accession : YP_004264507.1
Strain : Syntrophobotulus glycolicus DSM 8271
Genome accession: NC_015172
Putative virulence/resistance : Virulence
Product : two component transcriptional regulator, winged helix family
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 135406 - 136140 bp
Length : 735 bp
Strand : +
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: cce:Ccel_2106 two component transcriptional regulator, winged helix family; PFAM: Signal transduction r

DNA sequence :
ATGACGAAGTCATTAATCTATGTAGTTGAGGATGAAAGCCATATCCAGCAGCTCGTCAAATACAATTTAGAAAAAGAAGG
CTATAGGGTCAAAGCCTTTGGCAATGGAGAGAGCTTTTTACAGGAAACGCGCCTGAAGGTGCCGGAACTCTTTTTATTGG
ATATTATGCTGCCGGATATTGACGGCCTGGAATTATGCAAGCTCTTGAGGAAGAATCCTGCTACCCATAAAGTCCCCATT
ATCCTGTTAACCGCCAAAGGGGAGGAATTTGATAAGGTCCTGGGATTGGAGATCGGGGCGGATGACTATATCACCAAACC
TTTTAGCATCCGGGAAATGATCGCACGGGTCAAGGCTGTCCTCCGCAGGGTAACAGAGATTGGTGCTGAGGAGGAGGAAG
AGATCAGGCAAGGTGATATTGTGATGAATTGCAGCCGGCGGGAGGTCTATAAAGGCAGCCGCCAGCTTGATTTGACGCTC
AAGGAATTTGAGCTCTTAAAATTATTGCTGTTGAACAAAGGGCGGGTATTATCACGCGATATGCTTCTGGAAAAAATTTG
GGGTTACGAATATCAAGGAGAAACAAGGACGGTTGATGTGCATATTCGCTATTTGAGACAAAAGATTGAAGAGGATGACA
ACAATCCGCTTTATATAGAAACGGTCAGAGGGATCGGCTACCGTTTCAGTGACAAAGTATCGCGCACGGATTCGGAAACA
ACGAAGCGGTTATGA

Protein sequence :
MTKSLIYVVEDESHIQQLVKYNLEKEGYRVKAFGNGESFLQETRLKVPELFLLDIMLPDIDGLELCKLLRKNPATHKVPI
ILLTAKGEEFDKVLGLEIGADDYITKPFSIREMIARVKAVLRRVTEIGAEEEEEIRQGDIVMNCSRREVYKGSRQLDLTL
KEFELLKLLLLNKGRVLSRDMLLEKIWGYEYQGETRTVDVHIRYLRQKIEEDDNNPLYIETVRGIGYRFSDKVSRTDSET
TKRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 2e-29 42
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 2e-29 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_002952.2859905.p0 Protein 2e-40 49
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_007622.3794472.p0 Protein 2e-40 49
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_003923.1003749.p0 Protein 2e-40 49
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_002758.1121668.p0 Protein 2e-40 49
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_009641.5332272.p0 Protein 2e-40 49
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_013450.8614421.p0 Protein 2e-40 49
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_007793.3914279.p0 Protein 2e-40 49
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_002745.1124361.p0 Protein 2e-40 49
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_009782.5559369.p0 Protein 2e-40 49
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_002951.3237708.p0 Protein 2e-40 49
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_012469.1.7686381. Protein 2e-41 48
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family HE999704.1.gene2815. Protein 8e-39 48
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_012469.1.7685629. Protein 3e-37 47
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family AE016830.1.gene1681. Protein 8e-39 45
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_014475.1.orf0.gen Protein 1e-31 44
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_005054.2598277.p0 Protein 1e-31 44
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family CP000034.1.gene3671. Protein 7e-32 42
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family CP001918.1.gene3444. Protein 6e-28 42
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family CP000647.1.gene2531. Protein 2e-28 42
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family CP001138.1.gene2239. Protein 7e-28 42
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family BAC0596 Protein 7e-28 42
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family AE000516.2.gene3505. Protein 2e-31 42
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_003923.1003417.p0 Protein 1e-29 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_013450.8614146.p0 Protein 1e-29 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_002951.3238224.p0 Protein 1e-29 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_007793.3914065.p0 Protein 1e-29 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_002758.1121390.p0 Protein 1e-29 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_010079.5776364.p0 Protein 1e-29 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_002952.2859858.p0 Protein 1e-29 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_007622.3794948.p0 Protein 1e-29 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family CP004022.1.gene1676. Protein 5e-24 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family AM180355.1.gene1830. Protein 3e-25 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family CP000034.1.gene2186. Protein 7e-28 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family NC_002695.1.916589.p Protein 9e-28 41
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family BAC0039 Protein 7e-28 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family VFG1702 Protein 7e-30 42
Sgly_0135 YP_004264507.1 two component transcriptional regulator, winged helix family VFG1563 Protein 1e-29 41