Gene Information

Name : Sgly_0976 (Sgly_0976)
Accession : YP_004265318.1
Strain : Syntrophobotulus glycolicus DSM 8271
Genome accession: NC_015172
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 961701 - 963416 bp
Length : 1716 bp
Strand : +
Note : COGs: COG0804 Urea amidohydrolase (urease) alpha subunit; HAMAP: Urease, subunit alpha; InterPro IPR005848: IPR011612: IPR006680; KEGG: cth:Cthe_1816 urease subunit alpha; PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; PRIAM: Urease; SPTR: Urea

DNA sequence :
TTGAGCTGCACAATATCCGGCAGAGAGTATGCCAATATGTACGGGCCGACCAAAGGAGATAAGATCCGCCTGGCGGATAC
GGAGTTATGGGTGGAGATCGAACAGGACTGGACGGTTTACGGCGACGAATGCAAATTCGGCGGCGGCAAGTCCGTGCGGG
ACGGCATGGGGCAGTCCCCTTCCCGGTCCGGGGAAGAGGGCGCGCTGGACCTGCTGATCACCAACGCCGTCATCGTGGAT
TACAGCGGCATCATTAAAGCCGATATCGGGATAAAAAACGGAAAAATCGAAGGGATCGGCAAAGCGGGGAATCCGGATAT
CATGGACGGTGTCGCCCCCAATATGGTGATCGGCGCCGCGACGGAGGTCATTGCGGGCGAGGGCCTGATCGTGACCGCCG
GCGGCATCGATACCCATATTCATTTTATTTGCCCGCAGCAGATTGAAACCGCCCTTTACAGCGGCATGACAACCATGATC
GGCGGCGGGACCGGACCGGCGGACGGCACGAACGCCACGACCTGCACCCCCGGCAGATTCAACCTGCACAGGATGCTGGA
GGCGGCGGAAGCCTTTCCGGTGAATTTGGGCTTTTTGGGCAAGGGAAACGCTTCGTTCCCCAAGCCCCTGATCGAGCAGA
TCGAGGCCGGAGCGCTCGGGCTGAAGCTTCACGAGGACTGGGGGACAACCCCGGCAGCCATCGACGCCTGCCTCCGGGTC
GCCGACCAGTATGATGTTCAGGCTGCCATTCACACGGATACCCTGAACGAAGCGGGTTTTGTGGAAGACACGATCCGGGC
CATCGGCGGCAGGACGATCCATACCTACCATACCGAGGGAGCGGGCGGGGGACATGCTCCCGATATCATCAAAATAGCGG
CGCTGAGCAATATTCTTCCCTCGTCCACCAATCCGACCATGCCCTTTACCCGCAATACTCTGGATGAGCATCTGGATATG
CTGATGGTATGCCATCACCTGGACAGCCGGGTGCCGGAGGATATCGCCTTTGCCGATTCCAGAATCCGCCCCGAAACCAT
CGCGGCGGAGGATGTTCTGCATGATTTGGGCGTCTTCAGCATGATGAGCTCCGATTCTCAGGCGATGGGCCGGGTGGGCG
AGGTGATCATCCGCACCTGGCAAACCGCCGATAAGATGAAACGGCAGCGCGGCGCGTTGCCTCAAGAACGCGGCAACGAT
AATTTCCGGGTCAAGAGGTACATCGCCAAATATACGATTAATCCCGCCGTGACGCACGGGATCGCGGATTATGTGGGCTC
GGTGGAGCGCGGCAAGCTGGCCGATCTGGTTCTGTGGAAGCCGGAAATGTTCGGAGTGAAGCCGGAAATGATCTTAAAGG
GAGGGGTGATCACCGCGGGCAGAATGGGGGATGCCAATGCCTCCATCCCCACCCCTCAGCCTTTGCTTTACCGGAAGATG
TTCGGGGCGTTCGGGCGGGCCAAATACAGCGCCTGCGCCACATTTGTGTCCCAGGAATCCATAGACAACGGGACAATCGG
GGGATTGAACCTGAGTAAACAGATTCTGGCGGTGAAAAACTGCCGGAAGATCACCAAAAAGGATATGCGTCTCAATGACA
GCATGCCCTCGATCGAGGTCGATCCCGAAACCTATGAGGTCAGGGTGGACGGGGAAAGGATCAGCTGTGAAGCGGCGGAA
ACGCTGCCGCTGGCCCAGCGGTATTTTTTGTTCTGA

Protein sequence :
MSCTISGREYANMYGPTKGDKIRLADTELWVEIEQDWTVYGDECKFGGGKSVRDGMGQSPSRSGEEGALDLLITNAVIVD
YSGIIKADIGIKNGKIEGIGKAGNPDIMDGVAPNMVIGAATEVIAGEGLIVTAGGIDTHIHFICPQQIETALYSGMTTMI
GGGTGPADGTNATTCTPGRFNLHRMLEAAEAFPVNLGFLGKGNASFPKPLIEQIEAGALGLKLHEDWGTTPAAIDACLRV
ADQYDVQAAIHTDTLNEAGFVEDTIRAIGGRTIHTYHTEGAGGGHAPDIIKIAALSNILPSSTNPTMPFTRNTLDEHLDM
LMVCHHLDSRVPEDIAFADSRIRPETIAAEDVLHDLGVFSMMSSDSQAMGRVGEVIIRTWQTADKMKRQRGALPQERGND
NFRVKRYIAKYTINPAVTHGIADYVGSVERGKLADLVLWKPEMFGVKPEMILKGGVITAGRMGDANASIPTPQPLLYRKM
FGAFGRAKYSACATFVSQESIDNGTIGGLNLSKQILAVKNCRKITKKDMRLNDSMPSIEVDPETYEVRVDGERISCEAAE
TLPLAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 5e-168 67
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 5e-168 67
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-159 63
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-159 63
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-159 63
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-159 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sgly_0976 YP_004265318.1 urease subunit alpha VFG0270 Protein 4e-173 69