Gene Information

Name : Bacsa_0880 (Bacsa_0880)
Accession : YP_004257945.1
Strain : Bacteroides salanitronis DSM 18170
Genome accession: NC_015164
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 984047 - 986635 bp
Length : 2589 bp
Strand : +
Note : COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterPro IPR004176:IPR003959:IPR013093:IPR019489:IPR003593:IPR0177 30; KEGG: bvu:BVU_3815 endopeptidase Clp ATP-binding chain B; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal

DNA sequence :
ATGAACTTTAACAACTTTACAATCAAATCGCAAGAAGCTGTGCAAGAAGCGGTCAATCTGGTACAAAGCCGCGGACAGCA
AGCCATCGAGCCCGAACATTTGATGGCAGGGGTGCTGAAAGTAGGAGAAAATGTGACAAACTTCATTTTCCAGAAACTGG
GCATCAACGGCCAACAAATCGAAACGGTACTCGACAGGCAGATTGCTTCTCTGCCGAAGGTATCGGGAGGAGAACCCTAC
CTGAGCCGTGATGCAAACGAGGTATTGCAGAAAGCCATCGAATACTCGAAAGGATTAGGTGACGAGTATGTATCACTGGA
AGCGCTGCTGCTCGCTCTGCTGAATGTGAAGAGCACCGTTTCCACCATGCTGAAGGATGCCGGACTGACCGACAAGGAAC
TGCGTGCAGCCATCAGCGAACTGCGGCAAGGACAGAAAGTAACTTCGCAATCGAGCGAAGATACCTACCAGTCGCTGAAC
AAGTATGCCATCAACCTGATTGAGGCAGCCCGTACCGGAAAACTCGACCCCGTAATCGGACGTGATGAGGAAATCCGCCG
TGTGCTTCAGATATTAAGCCGGCGTACGAAGAACAACCCGATTCTGATTGGTGAGCCGGGTACCGGTAAGACCGCTATTG
TAGAAGGGCTTGCCCAACGTATCCTGCGTGGTGACGTACCCGAAAACCTGAAGAACAAACAGCTCTTCTCACTGGATATG
GGTGCGCTGATTGCCGGCGCCAAATACAAAGGCGAATTCGAAGAGCGGCTGAAATCGGTTATCAACGAGGTGAAGAAATC
AGAGGGAAACATCATCCTGTTCATTGATGAAATCCACACACTGGTAGGTGCAGGAAAAGGTGAAGGTGCCATGGATGCAG
CCAATATCCTGAAACCGGCATTGGCACGTGGCGAACTGCGGAGCATCGGTGCCACTACCCTTGACGAATACCAGAAGTAT
TTCGAAAAGGATAAAGCCTTGGAGCGTAGGTTCCAGACCGTCATGGTGGACGAACCCGACACGGCAAGCTCTATCTCTAT
CCTGCGTGGCTTGAAGGAGCGTTACGAGAACCACCACCAAGTGCGTATCAAAGACGAAGCCATCATTGCCGCCGTAGAAC
TGAGCAACCGTTACATCACCGACCGTTTCTTGCCCGATAAGGCTATCGACCTGATGGACGAGGCAGCCGCAAAACTCCGT
ATGGAGCGTGATTCGCTTCCCGAAGAGCTGGACGAAATCGAACGCCGGTTGAAACAACTGGAAATCGAGCGCGAAGCCAT
CAAGCGGGAAAAGGATGAAGCCAAACTTGCCCAGCTGAACAAGGAAATAGCCGAACTCAAGGAACAAGACACTTCTTACA
AAGCCAAATGGCAGAGCGAGAAGGAACTGGTGAACAAGATACAGCAGAACAAGAAGGAAATCGAGCAATTGAAGTTCGAA
GCCGACCGTGCCGAACGTGAAGGCGACTACGGAAAAGTGGCAGAAATCCGATACGGAAAACTGCAGGCATTGGAAAACGA
AATCAAGAGCATCCAAGAAGACCTGAAGAAAAAGCAGGGCGACAACGCCATGATTAAGGAAGAGGTAACTGCCGAGGATA
TAGCCGATGTAGTATCGCGCTGGACGGGAATACCGGTAAGCAAGATGCTGCAAAGCGAACGCGACAAGCTGCTCCATTTG
GAAGACGAACTGCACAAACGTGTTATCGGACAAGACGAAGCCATCGAAGCCGTAGCAGACGCCGTGCGCCGGAGCCGTGC
AGGACTGCAAGACCCGAAACGCCCCATCGGCTCGTTCATCTTCCTGGGCACCACCGGTGTAGGTAAGACCGAACTGGCAA
AAGCACTGGCAGAATACCTGTTCGATGACGAATCGCTGATGACCCGTATTGACATGAGTGAGTATCAGGAGAAACATACC
GTCTCGCGTCTAATTGGTGCGCCTCCGGGATACGTAGGTTATGACGAGGGCGGTCAGCTGACCGAAGCCGTGCGCCGGAA
ACCTTACTCGGTCGTACTGTTCGATGAAATCGAGAAAGCGCACCCTGATGTCTTCAATATCCTGCTTCAGGTATTGGACG
ACGGACGTCTGACGGACAATAAGGGACGTACGGTGAACTTCAAGAACACCATCATCATCATGACCTCCAACTTGGGAAGC
TCATACATACAAAGTCAGTTTGAGAAGATTAACGACCAGAACCATGACCAGATTGTAGAAGACACCAAGAAAGAAGTGAT
GGAGATGCTGAAAAAGACCATCCGTCCGGAGTTCTTGAACCGTATCGATGAAATCATCATGTTCCAGCCGTTGGATAAAG
ACCAAATCAAGCAGATTGTACGCCTGCAAATCAACGGCATACAGAAGATGCTTGCCGACAATGGCGTAACACTACAGATG
ACCGACGAAGCCGTCGAGTTCCTTGCTACGGCAGGATTCGACCCCGAATTCGGTGCACGTCCGGTCAAGCGTGCCATCCA
GCGTTACCTGCTCAACGATTTGTCGAAGAAACTGCTGGCTCAGGAAGTCGACCGCACAAAACCGATTGTGGTAGAACGCA
ATGCCGACGGATTGAAGTTCCGCAACTGA

Protein sequence :
MNFNNFTIKSQEAVQEAVNLVQSRGQQAIEPEHLMAGVLKVGENVTNFIFQKLGINGQQIETVLDRQIASLPKVSGGEPY
LSRDANEVLQKAIEYSKGLGDEYVSLEALLLALLNVKSTVSTMLKDAGLTDKELRAAISELRQGQKVTSQSSEDTYQSLN
KYAINLIEAARTGKLDPVIGRDEEIRRVLQILSRRTKNNPILIGEPGTGKTAIVEGLAQRILRGDVPENLKNKQLFSLDM
GALIAGAKYKGEFEERLKSVINEVKKSEGNIILFIDEIHTLVGAGKGEGAMDAANILKPALARGELRSIGATTLDEYQKY
FEKDKALERRFQTVMVDEPDTASSISILRGLKERYENHHQVRIKDEAIIAAVELSNRYITDRFLPDKAIDLMDEAAAKLR
MERDSLPEELDEIERRLKQLEIEREAIKREKDEAKLAQLNKEIAELKEQDTSYKAKWQSEKELVNKIQQNKKEIEQLKFE
ADRAEREGDYGKVAEIRYGKLQALENEIKSIQEDLKKKQGDNAMIKEEVTAEDIADVVSRWTGIPVSKMLQSERDKLLHL
EDELHKRVIGQDEAIEAVADAVRRSRAGLQDPKRPIGSFIFLGTTGVGKTELAKALAEYLFDDESLMTRIDMSEYQEKHT
VSRLIGAPPGYVGYDEGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRTVNFKNTIIIMTSNLGS
SYIQSQFEKINDQNHDQIVEDTKKEVMEMLKKTIRPEFLNRIDEIIMFQPLDKDQIKQIVRLQINGIQKMLADNGVTLQM
TDEAVEFLATAGFDPEFGARPVKRAIQRYLLNDLSKKLLAQEVDRTKPIVVERNADGLKFRN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-160 50
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-117 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-107 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-107 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bacsa_0880 YP_004257945.1 ATP-dependent chaperone ClpB VFG2076 Protein 3e-133 46
Bacsa_0880 YP_004257945.1 ATP-dependent chaperone ClpB VFG2084 Protein 4e-116 44