Gene Information

Name : Bacsa_0378 (Bacsa_0378)
Accession : YP_004257451.1
Strain : Bacteroides salanitronis DSM 18170
Genome accession: NC_015164
Putative virulence/resistance : Resistance
Product : chloramphenicol O-acetyltransferase
Function : -
COG functional category : R : General function prediction only
COG ID : COG0110
EC number : 2.3.1.28
Position : 425633 - 426268 bp
Length : 636 bp
Strand : -
Note : COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: bfs:BF1528 acetyltransferase; PRIAM: Chloramphenicol O-acetyltransferase; SPTR: uncharacterized protein

DNA sequence : 
ATGAAAAAGATATATCCACGCACAGGCGACACGCAGACCGTGTACCTGAATGCCGTCGTGAAAGCCCCGTCTATCGAGGT
GGGAGACTATACCATCTATAATGATTTTGTGTCCGACCCGTTGCTTTTCGAGCAAAATAATGTGCTTTACCATTACCCTA
TCAACCACGAGCGGCTGATAATCGGCAAGTTCTGTTCCATTGCCTGCGGCGCGAAATTCCTGTTCAACTGTGCCAACCAT
ACCTTAAAATCCCTATCCACTTACACCTTCCCGCTCTTTTATGAAGACTGGGATTTGGAGAAATCGGACGTGGCAACGGC
TTGGGACAACAAAGGTGACATCGTGATAGGCAACGATGTGTGGATAGGCTATGAAGCGGTGATTATGGCTGGTGTTCACA
TCGGCAATGGGGCAATCATAGCCGCCCGTGCCGTTGTTACGAAAGACGTGCCGCCCTATACGATAGTCGGCGGTGTTCCT
GCCCGACCGATAAGGAAGCGTTTCGATGAAGAAGTGATACAGGAACTTGAAACGCTGCAATGGTGGAATTGGTCTGCCGA
GAAGATACGGAGATGCTTGGCTTATATCGGGAATGGTGATGTGAACGGATTGCTTCAAATGCAAGGTGGTAAGTAG

Protein sequence : 
MKKIYPRTGDTQTVYLNAVVKAPSIEVGDYTIYNDFVSDPLLFEQNNVLYHYPINHERLIIGKFCSIACGAKFLFNCANH
TLKSLSTYTFPLFYEDWDLEKSDVATAWDNKGDIVIGNDVWIGYEAVIMAGVHIGNGAIIAARAVVTKDVPPYTIVGGVP
ARPIRKRFDEEVIQELETLQWWNWSAEKIRRCLAYIGNGDVNGLLQMQGGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
catB8 YP_005797132.1 chloramphenicol acetyltransferase Not tested AbaR4e Protein 1e-28 46
catB3 AET25385.1 chloramphenicol acetyltransferase Not tested PAGI-2(C) Protein 6e-29 42
catB3 AFG30108.1 chloramphenicol acetyltransferase Not tested PAGI-2 Protein 6e-29 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bacsa_0378 YP_004257451.1 chloramphenicol O-acetyltransferase AM180355.1.gene2499. Protein 4e-66 61
Bacsa_0378 YP_004257451.1 chloramphenicol O-acetyltransferase AY123251.gene2.p01 Protein 4e-29 46
Bacsa_0378 YP_004257451.1 chloramphenicol O-acetyltransferase JF268688.1.gene6.p01 Protein 1e-27 43
Bacsa_0378 YP_004257451.1 chloramphenicol O-acetyltransferase AF322577.2.gene4.p01 Protein 3e-29 42
Bacsa_0378 YP_004257451.1 chloramphenicol O-acetyltransferase AY740681.1.gene5.p01 Protein 3e-29 42