Gene Information

Name : SpiBuddy_0263 (SpiBuddy_0263)
Accession : YP_004246295.1
Strain : Sphaerochaeta globosa Buddy
Genome accession: NC_015152
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : 1.1.1.22
Position : 289298 - 290593 bp
Length : 1296 bp
Strand : +
Note : TIGRFAM: nucleotide sugar dehydrogenase; KEGG: elm:ELI_2699 UDP-glucose/GDP-mannose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-termi

DNA sequence :
ATGATTGTCAGAGATTTGGTTATTTCTATAATTGGATTGGGCTATGTAGGTATGCCTATCGCTGTTGCTTTTGCAAAAAA
GGTGAAAGTAATTGGCTTTGACATAAACATAGCAAAGGTTGAACTCTATAAAGCTGGCATCGATCCTACGAGAGAAGTTG
GTAATGAAATTATCAAAAATACCTCAGTGGAGTTTACAAGTGACGAAACCAAGCTGAGGGAAGCAAGATTTCACATAGTA
GCTGTGCCAACTCCAGTTTATGACGATCATACTCCTGACCTCAGCCCAGTAGAAGGTGCAAGCAGGGTATTGGGAAAGAA
CCTTGAGAAAGGATCAATTGTTGTTTTCGAATCTACCGTGTACCCAGGTGTAACTGAGGATATTTGCGTACCAATACTAG
AAAAAGAATCTGGGCTTAAGTGCGGTGTTGATTTTTTTGTTGGTTATTCTCCAGAACGAATCAATCCTGGTGATAAAGTT
CATCGTTTGGAAACAATAATAAAAATAGTATCTGGTATGGATGCCCAGACATTGGATACTGTTGCCATGGTGTATGAACT
GGTAGTTGAGGCAGGTGTTTATAGAGCACCATCAATTAAGGTAGCTGAAGCTGCTAAGGTAATTGAGAATAGCCAGCGGG
ATATCAATATTGCCTTCATGAATGAGTTGTCAATAATTTTTAATAAGTTAGGAATTAGCACAAAAGAAGTGTTGGATGCT
GCTTCAACGAAGTGGAATTTTCTTAAGTTCTCGCCTGGCTTAGTTGGCGGTCATTGCATTGGAGTAGACCCATATTATCT
TACCTATAAGGCTGAACAGCTTGGATACCATTCGCAAATCATCCTATCGGGAAGGCGAATTAACGACGATATGGGAAGAT
ATGTTGCTGAGAACGTGGTAAAGAAGTTAATCTCTGTAGGTTCCCCGGTAAAAGGAGCCAAAGTTCTTGTTCTTGGATTT
ACATTCAAAGAGAATTGCCCTGATACGCGAAACACCAAGGTAATAGATATCATTAATGAGCTTAGAGAGTATGGCATAGA
ACCTATGGTATGTGATCCTGTTGCTGACTCTCAAGAAGCGGAATATTTGTACGGAATCTCTTTTGTTTCTAGACAAAGTA
TAAAGAAAGTTAATGCTGTGATTGTTGCTGTTGCTCATAATGAATTTTTAACATATGGGATACGAGAGCTTGATAGTTTT
TTTGCATGTGACACTGAGAAGGTTGTGATCGATGTGAAATCGATTCTCAACCGTAATGAGTTTGAACAGGCTGGTTACTG
TTATTGGAGTTTATAA

Protein sequence :
MIVRDLVISIIGLGYVGMPIAVAFAKKVKVIGFDINIAKVELYKAGIDPTREVGNEIIKNTSVEFTSDETKLREARFHIV
AVPTPVYDDHTPDLSPVEGASRVLGKNLEKGSIVVFESTVYPGVTEDICVPILEKESGLKCGVDFFVGYSPERINPGDKV
HRLETIIKIVSGMDAQTLDTVAMVYELVVEAGVYRAPSIKVAEAAKVIENSQRDINIAFMNELSIIFNKLGISTKEVLDA
ASTKWNFLKFSPGLVGGHCIGVDPYYLTYKAEQLGYHSQIILSGRRINDDMGRYVAENVVKKLISVGSPVKGAKVLVLGF
TFKENCPDTRNTKVIDIINELREYGIEPMVCDPVADSQEAEYLYGISFVSRQSIKKVNAVIVAVAHNEFLTYGIRELDSF
FACDTEKVVIDVKSILNRNEFEQAGYCYWSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-107 56
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 4e-93 53
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 4e-93 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SpiBuddy_0263 YP_004246295.1 nucleotide sugar dehydrogenase VFG0431 Protein 2e-93 53