Gene Information

Name : SpiBuddy_1109 (SpiBuddy_1109)
Accession : YP_004247128.1
Strain : Sphaerochaeta globosa Buddy
Genome accession: NC_015152
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1189500 - 1191824 bp
Length : 2325 bp
Strand : +
Note : SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain; TIGRFAM: DNA topoisomerase III, bacterial-type; KEGG: cce:Ccel_0922 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, central; Toprim domain

DNA sequence :
TTGAAAAAGCTTGTACTTGCTGAAAAGCCGAGTGTTGGAAGAGAGTTGGCACGTGTTCTGAATTGCTATAAACGGGAAAC
CGGATATATAGAAGGCGAGCACTACATCGTCACCTGGGCCTTGGGACATCTGGTGGAATTGGCACAGCCGGCAGCGTACA
GTGAACGCTATAAGCGATGGTCGCTGCGTGATCTCCCCATGCTGCCCCCTGTTTTGCAACAGGAAGTCATCGAGCAGAGC
AAGGACCAGTTTGCAGTGGTAAAAAGCTTGATCAAGCGCCCCGATATCGAGAGTCTGGTCATTGCAACCGATGCCGGACG
CGAAGGGGAATTGGTAGCCCGCTGGATTATGAAGCTTGCAGACTATCAAGGCCCAGCGCACCGACTATGGATCAGCAGCC
AGACTGAAGGGGCCATTAAGGAAGGGTTTGCCAACCTCAAGGAAGCAAGCTTGTATGACAACCTGTACAAGGCAGCCGAA
AGCAGGGCCGCCGCCGATTGGTATGTCGGTATGAATGTCACCAGAGCCCTAACCTGCCATTACGATGCAAAGCTTTCCGC
AGGCAGAGTACAGACTCCGACTTTGGCCCTCATGACCAGGCGTGAAGATGAGATTGAAGCTTTCAGCGGACAATTCTATT
GGACACTCAAGGCAGATTTCATCCATTTCAGTGCTTCCTATTATCCAACGGAGGATACGATCAGGATCACCGAGGAGGCA
ACGGCCAAGGCTTTGGAGGCCTCACTGGTCGGCAAGCAGGGAAGGGTGGTGAGTTTGGAAACGGTACAGAGGAATGAACA
GCCTCCACTTGCCTATGACCTGACCGAACTGCAGCGCGATGCAAACAACTTACTTGACTTCAGTGCCAAACAGACATTGG
ATGTGCTGCAGGCCCTGTATGAGCAACATAAGATAGTTACCTATCCGAGAACCGATAGCCGTTACATCACCACCGATATT
GTAGCTACGCTTCCCGATCGCCTCCGTTCCCTGGCGGACACACCATTCGCTCCTCTCTGCAGTGGTTTTGTCAAGGACGG
GTTCCGTGTAGACGAGGAGCGCTTTGTCCAGGATCTGCAGGTAACCGATCACCATGCCATTATCCCAACCGAACAACGGG
TGAATCTATCAAGGCTCAATGCCCAAGAAAAGGCTCTCTGGGAGTTGATAGTTCTGCGCTTTTTGGAAGTGCTCAGTCCC
GATTACATCTACCAGACCACTACCTTGATAGCCGAGGTTGAGGAAAGCCGGTTCAAGACCCGGCTCACCATCCCTGTCCA
GCAAGGGTGGAGAAGTGTAGCCACCTTGATCGGCAAGCGAAGCGCCCAGGCTTCATTGGGCGAGGAGGATGAGGCAAGTC
CTGCCTTGTTGAGCCTGAAGCAGGGTGATGGACTTACCATTTCATCGCTCAAGCTCAGAAAGCTTGCCACAACCGCTCCC
TCCCGCTATACCGAAGCAACCTTGCTCTCTGCCATGGAACATGCAGGACGGTTTGTCGATGACGCAAAACTGAAAAAGCG
GCTGTCCAATGGTTTAGGTACTCCTGCCACCCGCGCAGATATTATTGAGAAGCTGATCCAGAACCATTACATCGAGCGGG
CAGGCAAGGAACTGGTTCCCACCCCAAAGGGAAGGGAACTGGTTCGCCTTGCCCCGGAAGAGCTTCGCTCACCTGAATTG
ACCGGTCGTTGGGAAGAGAGACTTGGCAATATCGCAGAAGGGAAAGAGAATGGCGATTTGTTCATTCAGGATATCAAGCG
TAATGCTTCAGCCCTGGTTACTCAGGTGACCGGTAGCAGCGATGTCTTTTCGCCGCATTTTCCCGACGCCAAGCAGTGTC
CCTACTGCAAAACACCCATGATGAAGGTTGTTGATGAGATCGGGCAGAATCACTATCTCTGCCAGAAGCTTTCTTGCAGT
TATGAGGAGATGGAAGTCAAGAAACGAGTACCAAAACCCCAAGCTGCAAAGCCGGTGGAACCGGAAAAGAAAATGGTGGT
CAAGGTTAAGGCAGTCGAAACCGACAGTGTGAAAAAACGGGTGGTAGTGAAAAAGAAGGCTCCCGTCCAAGCTTTTTCCC
TGCCTGATGAAGTTGAGGCTCCGTCCTATACGTGGGAGACGGTCATCGAGGTGGTAAGGCCAAGCAAACTTGCTTTCCGC
GCAGAGAGGAATGAACGGCCACCTGAAAACAGGGGTGGGTGGAGATCCCCGGTTCAATCGTCACATCTGGTGGAGCAGAC
TCCTTCCGAGGGTGGAAGCTTTGCTGATTTTCTTAAGCTGAATGAAGAAAGAAAGAAGCGCGATCGCGATAAAAAGCGTA
AGTAA

Protein sequence :
MKKLVLAEKPSVGRELARVLNCYKRETGYIEGEHYIVTWALGHLVELAQPAAYSERYKRWSLRDLPMLPPVLQQEVIEQS
KDQFAVVKSLIKRPDIESLVIATDAGREGELVARWIMKLADYQGPAHRLWISSQTEGAIKEGFANLKEASLYDNLYKAAE
SRAAADWYVGMNVTRALTCHYDAKLSAGRVQTPTLALMTRREDEIEAFSGQFYWTLKADFIHFSASYYPTEDTIRITEEA
TAKALEASLVGKQGRVVSLETVQRNEQPPLAYDLTELQRDANNLLDFSAKQTLDVLQALYEQHKIVTYPRTDSRYITTDI
VATLPDRLRSLADTPFAPLCSGFVKDGFRVDEERFVQDLQVTDHHAIIPTEQRVNLSRLNAQEKALWELIVLRFLEVLSP
DYIYQTTTLIAEVEESRFKTRLTIPVQQGWRSVATLIGKRSAQASLGEEDEASPALLSLKQGDGLTISSLKLRKLATTAP
SRYTEATLLSAMEHAGRFVDDAKLKKRLSNGLGTPATRADIIEKLIQNHYIERAGKELVPTPKGRELVRLAPEELRSPEL
TGRWEERLGNIAEGKENGDLFIQDIKRNASALVTQVTGSSDVFSPHFPDAKQCPYCKTPMMKVVDEIGQNHYLCQKLSCS
YEEMEVKKRVPKPQAAKPVEPEKKMVVKVKAVETDSVKKRVVVKKKAPVQAFSLPDEVEAPSYTWETVIEVVRPSKLAFR
AERNERPPENRGGWRSPVQSSHLVEQTPSEGGSFADFLKLNEERKKRDRDKKRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB-2 NP_815968.1 DNA topoisomerase III Not tested Not named Protein 2e-104 41