Gene Information

Name : Asphe3_40770 (Asphe3_40770)
Accession : YP_004243279.1
Strain :
Genome accession: NC_015146
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 87612 - 89150 bp
Length : 1539 bp
Strand : +
Note : PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: mercuric reductase

DNA sequence :
ATGCAGAGCTGGTCTTCGGTTGAAGGCTGCACATGGCGGTCGGTTGAGCAACAGGTGTGCTGGCGGCTGCTTCCCTTCCA
TCTTCAGGAGTCCCTCGTGTCGGCAGCATCTTTCGATTATGACCTGGCCATTATCGGTTCCGGCGGGGCTGCTTTCGCTG
CGGCCATCCGGGCAACCAGCCGTGGCAAGCGGGTGTTGATGGTGGAGCGCAGCACTGTGGGAGGCACGTGCGTGAACACG
GGCTGCATCCCGTCCAAGGCCCTGCTGGCCGCCGCGGAAGCCCGCCATGTCGCCCTCGATGCTTCCGGACGGTTCCCCGG
TATCAGCACCTCCGCAGAGCCGGTGGATATGCCCGAACTGGTCGCCGGGAAGCGCTCACTGGTCGAATCCATGCGGTCAG
AGAAGTATGTGGATCTCGCCGCGGGCTATGGATGGAACCTGCAGCGGGGGACGGCGGTGTTCGCCGGAACCGCAGCCGCA
CCGGTTTTGAACATCACCGCCCCGGGCGGAACCACCGAGACAGTCAGCGCGGAACACTACCTGGTCGCGACCGGCTCCAC
CCCCTGGATCCCTGAAGTGCCGGGAATGGACGAGGTGGATTATCTGACGTCCACGAGTGCGATGGAGCTGCAGGACGTTC
CCGCTTCGATGCTGGTGGTGGGCGGCGGGTATGTGGCGCTGGAGCAGGCGCAGCTTTTCGCCCGGCTCGGCACGGAGGTG
ACCATCCTGGTCCGGTCCAAGCTCGCCTCGGCCGAAGAGCCTGAAGCCGGGCATGCCCTCGCCGGTGTCTTCGCCGATGA
GGGCATCCGGGTCGTCCGTCGAGCGACAGCGTCCTCGGTCCGGACCGATGAGGTGTCGGGGGACGTGGTCGTGGATGCTT
CCGTCTCAGGAGGAAACGAGGAATTCAGGGCCGCGCGCCTGCTCATGGCAACAGGCCGGCGCCCGGTCACGGAGGATTTG
AACCTTTGCATGGTCGGCGTTGAAACCGGGGACCGCGGGGAAGTCCTGGTCGACGGGAGCCTTCGCAGTACTAATCCGAG
GATCTGGGCCGCGGGTGATGTGACGGGTCACCCGGAGTTCGTTTACGTCGCCGCCGCGCACGGGGCCCTGATGGTGGAGA
ACGCCTTTGAGGGTGCCGGGCGTGAGGTCGATTACCGGCACCTGCCCCGGGTCACGTTTACCAGCCCTGCCCTGGCCGCT
GTCGGGATGACGGACAAGGAAGCGAACCAGGCAGGGATCCGGTGCATGTGCCGGGTTCTGCCGCTCAAATTTATCCCTCG
CGCGCTGGTGAACCGTGATACCCGCGGCTTCATCAAGATCGTTGCCGACGCGGACACGGGTCGGATTGTAGGGATCACTG
TCGTGGGTAAGGACGCCGGGGACATCGCCGCCGCAGGGATTTACATTCTGGAGGCCGGGATGACCGTTGATCAGGTCGCG
AATCTCTGGAGCCCCTATCTGACCATGGCCGAAGGCATCAAGATAGCAGCCCAGTCCTTCACTACTGACGTCTCCAAACT
GTCCTGTTGCGCGGCATGA

Protein sequence :
MQSWSSVEGCTWRSVEQQVCWRLLPFHLQESLVSAASFDYDLAIIGSGGAAFAAAIRATSRGKRVLMVERSTVGGTCVNT
GCIPSKALLAAAEARHVALDASGRFPGISTSAEPVDMPELVAGKRSLVESMRSEKYVDLAAGYGWNLQRGTAVFAGTAAA
PVLNITAPGGTTETVSAEHYLVATGSTPWIPEVPGMDEVDYLTSTSAMELQDVPASMLVVGGGYVALEQAQLFARLGTEV
TILVRSKLASAEEPEAGHALAGVFADEGIRVVRRATASSVRTDEVSGDVVVDASVSGGNEEFRAARLLMATGRRPVTEDL
NLCMVGVETGDRGEVLVDGSLRSTNPRIWAAGDVTGHPEFVYVAAAHGALMVENAFEGAGREVDYRHLPRVTFTSPALAA
VGMTDKEANQAGIRCMCRVLPLKFIPRALVNRDTRGFIKIVADADTGRIVGITVVGKDAGDIAAAGIYILEAGMTVDQVA
NLWSPYLTMAEGIKIAAQSFTTDVSKLSCCAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-83 45
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-83 45
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 5e-63 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Asphe3_40770 YP_004243279.1 mercuric reductase BAC0224 Protein 1e-80 46
Asphe3_40770 YP_004243279.1 mercuric reductase BAC0651 Protein 1e-83 45