Gene Information

Name : Asphe3_03740 (Asphe3_03740)
Accession : YP_004239723.1
Strain : Arthrobacter phenanthrenivorans Sphe3
Genome accession: NC_015145
Putative virulence/resistance : Virulence
Product : urease
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 391108 - 392853 bp
Length : 1746 bp
Strand : +
Note : PFAM: Amidohydrolase family; Urease alpha-subunit, N-terminal domain; TIGRFAM: urease, subunit alpha

DNA sequence :
GTGAGCTTTGAGATCCCCCGCCGGCAGTACGCCGATTTGTACGGCCCCACCACCGGCGACGCGATCCGCCTGGCGGACAC
CGACTTGTTCCTCGAGATCGAGAAAGACCTTACGGTCTACGGGGAGGAGGTGGTCTTTGGCGGCGGCAAAGTGATCCGGG
ACGGCATGGGCCAGAACGGGCAGGTGACACGCGACGGGGATCCTGAAGATGACGGCGTCCCGGATACAGTCATCACCAAC
GCCGTGATCCTGGACTACACCGGCATCTACAAGGCCGATGTGGCACTCAAGGACGGCCATATCTTCAGGATCGGCAAGGC
CGGCAACCCGCAGATCACGGACGGCGTGGACATCGTGATCGGCGCCAGCACCGAAATCATCGCCGGCGAACGCAAGATCC
TCACCGCCGGGGGAGTGGACACGCACATCCACTTCATCTCCCCGGACCAGATCCCCGCGGCCCTGACCAGCGGCATCACC
ACCATGATCGGCGGCGGCACCGGCCCGGCCGAGGGCACCAAGGCCACCACGGTGACACCGGGGAAGTGGCACATCCAGCG
GATGCTCCAAGCCGCCGAAGGCTTCCCCATGAACATCGGCCTGTTCGGCAAAGGCCACGCGTCCGCCGTCGAACCCCTTG
CCGAGCAGATCCGGGCCGGTGCGGTCGGGCTGAAGGTCCACGAGGACTGGGGGTCCACCACCTCCTCCATCGACACGTCC
CTGACCGTCGCCGACGAATACGATGTCCAGGTTGCCATCCACACCGACACCCTGAACGAGTGCGGCTTCGTGGAGGACAC
CATCCGGGCCATCAACGGCAGGGTCATCCACACGTTCCATACCGAGGGAGCAGGCGGCGGGCACGCGCCGGACATCATCA
AGATCGCGGGGATGCCGAACGTCCTGCCTGCGTCCACCAACCCCACACTGCCGTACACCCGGAATACCATCGAGGAGCAC
CTGGACATGCTCATGGTGTGCCACCACCTCAACCCGGACATTCCCGAGGACGTCGCCTTCGCCGATTCCCGCATCCGGGC
CGAAACCATCGCGGCCGAGGACGTCCTGCAGGACCTCGGCATCTTCTCCATCACCTCCTCCGATTCCCAGGCGATGGGCC
GGGTGGGCGAGGTGATCACCCGCACCTGGCAGGTGGCGGACAAGATGAAGAAGCAGCGCGGGGTTTTGGAGGATGACGAC
GGCGGGGCCCACGGCAGTGCGGGCAGCGACAACTTCCGGCTCAAGCGCTACGTGGCCAAGTACACCATCAACCCGGCCAT
CGCCCAGGGCATCGCCGACACCGTCGGCTCCGTGGAGGTGGGCAAGTTCGCGGACCTGGTGCTGTGGGATCCTGCCTTCT
TCGGCGTGAAACCCGAGCTGGTACTCAAGGGCGGGCAGATCGCGTATGCGCTCATGGGGGATGCCAACGCCTCCATCCCC
ACCCCGCAGCCGCGCAGCATGCGCCCCATGTTCGCCGCGTTCGGCAAGGCAGTCCAGCAGTGCTCGATCACCTTCCTGTC
CCAGGCGGCGATCGACGCCGGCGTCCCCCACGAACTGGGGTTGGAGAAGGTCATCCGGCCCGTTTCCGGAATCCGTACGC
TCACCAAAGCCGACCTCAAGTACAACGACGCCACCCCGGACATCCAGGTGGACCCGGAAACCTATCAGGTCACGGTCGAC
GGCGAGGACGTCACCTGCGAGCCGTCCGACGTCCTGCCCATGGCGCAGCGCTACTTCCTCTTCTGA

Protein sequence :
MSFEIPRRQYADLYGPTTGDAIRLADTDLFLEIEKDLTVYGEEVVFGGGKVIRDGMGQNGQVTRDGDPEDDGVPDTVITN
AVILDYTGIYKADVALKDGHIFRIGKAGNPQITDGVDIVIGASTEIIAGERKILTAGGVDTHIHFISPDQIPAALTSGIT
TMIGGGTGPAEGTKATTVTPGKWHIQRMLQAAEGFPMNIGLFGKGHASAVEPLAEQIRAGAVGLKVHEDWGSTTSSIDTS
LTVADEYDVQVAIHTDTLNECGFVEDTIRAINGRVIHTFHTEGAGGGHAPDIIKIAGMPNVLPASTNPTLPYTRNTIEEH
LDMLMVCHHLNPDIPEDVAFADSRIRAETIAAEDVLQDLGIFSITSSDSQAMGRVGEVITRTWQVADKMKKQRGVLEDDD
GGAHGSAGSDNFRLKRYVAKYTINPAIAQGIADTVGSVEVGKFADLVLWDPAFFGVKPELVLKGGQIAYALMGDANASIP
TPQPRSMRPMFAAFGKAVQQCSITFLSQAAIDAGVPHELGLEKVIRPVSGIRTLTKADLKYNDATPDIQVDPETYQVTVD
GEDVTCEPSDVLPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 67
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 67
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 0.0 67
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 67
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-174 66
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-174 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Asphe3_03740 YP_004239723.1 urease VFG0270 Protein 1e-159 63