Gene Information

Name : Asphe3_35000 (Asphe3_35000)
Accession : YP_004242736.1
Strain : Arthrobacter phenanthrenivorans Sphe3
Genome accession: NC_015145
Putative virulence/resistance : Virulence
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 3724800 - 3726338 bp
Length : 1539 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase family; TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase

DNA sequence :
ATGACGACCTCAACCGAAACCACCACGCACTACGTGCCGCAGGACCTTCCCACCCACATCCAGCACTACATCGACGGCCA
GTTCGTCGACTCCGTGGGCGGCAAGACTTTCGACGTCCTGGACCCGGTGTCCAACCGGAACTACGCCACCGCCGCAGCAG
GCCAGAAAGAGGACATCGACCTCGCCGTGGCCGCCGCCCGGGAAGCGTTCACCAACGGACCGTGGCCGAAGATGAAGCCG
CGCGAACGCGCCCGCGTCCTGAACCGGATCGCCGACGCGGTCGAGGCCCAGGAAGCGCGCCTCGCCGAACTGGAGACCTT
CGATACCGGCCTGCCGATCACCCAGGCCAAGGGCCAGGCCCTGCGCGCGGCTGAGAATTTCCGGTTCTTCGCGGACCTGA
TCGTGGCCCAGTTCGACGACGCCATGAAGGTTCCGGGCTCACAGATCAACTACGTGAACCGGAAGCCGATCGGCGTGGCC
GGCCTGATCACGCCGTGGAACACCCCGTTCATGCTTGAGTCCTGGAAGCTCGCCCCGGCCCTGGCCACCGGCAACACCGT
GGTCCTCAAGCCCGCGGAGTTCACGCCTCTGTCCGCGTCCCTGTGGGCCACCATCTTCAAGGACGCAGGCCTGCCCGACG
GCGTCTTCAACCTGGTCAACGGCCTTGGCGAGGAAGCCGGCGACGCCCTGGTCAAGCACCCGGACGTGCCGCTGGTCTCC
TTCACCGGCGAGACCACCACCGGCCAGACGATCTTCCGCAACGCCGCCGCCAACCTCAAGGGCCTCTCGATGGAACTCGG
CGGCAAGTCCCCCTGCGTCGTGTTTGCCGACGCGGACGTGGATGCCGCGATCGATTCGGCCCTGTTCGGCGTCTTCTCCC
TCAACGGCGAACGCTGCACCGCAGGCTCCCGCATCCTGGTGGAACGCGCCATCTACGACGAGTTCTGCGAAAAGTACGCC
GCCCGGGCAAAGAACATCGTGGTGGGCGACCCGCACGACCCCAAGACCGAGGTGGGTGCCCTGGTCCACCCCGAGCACTA
CGAAAAAGTGGCCTCCTACGTGGAGATCGGCAAGTCCGAAGGCCGGCTCCTGGCCGGCGGCGGCCGCCCGAGCCACCTCC
CCGAGGGCAACTACATTGCACCCACCGTGTTCGCCGACGTCTCCCCCGATGCCCGGATCTTCCAGGAGGAAATCTTCGGC
CCCGTCGTCGCCATCACCCCATTCGAGAACGACGACGAGGCCCTCGCCCTGGCCAACAACACCAAGTACGGCCTGGCCGC
CTACATCTGGACCCAGAACCTCACCCGGGCGCACAACTTCTCGCAGAACGTCGAAGCCGGCATGGTCTGGCTGAACAGCC
ACAACGTCCGCGACCTGCGCACCCCGTTCGGCGGCGTCAAGGCCTCCGGCCTGGGCCACGAAGGCGGCTACCGCTCCATC
GACTTCTACACCGACCAGCAGGCCGTCCACATCACCCTCGGCACCGTCCACACTCCGAAGTTCGGCAGCATCGAGGACTC
CGCTGCCAACGAAGGCTAG

Protein sequence :
MTTSTETTTHYVPQDLPTHIQHYIDGQFVDSVGGKTFDVLDPVSNRNYATAAAGQKEDIDLAVAAAREAFTNGPWPKMKP
RERARVLNRIADAVEAQEARLAELETFDTGLPITQAKGQALRAAENFRFFADLIVAQFDDAMKVPGSQINYVNRKPIGVA
GLITPWNTPFMLESWKLAPALATGNTVVLKPAEFTPLSASLWATIFKDAGLPDGVFNLVNGLGEEAGDALVKHPDVPLVS
FTGETTTGQTIFRNAAANLKGLSMELGGKSPCVVFADADVDAAIDSALFGVFSLNGERCTAGSRILVERAIYDEFCEKYA
ARAKNIVVGDPHDPKTEVGALVHPEHYEKVASYVEIGKSEGRLLAGGGRPSHLPEGNYIAPTVFADVSPDARIFQEEIFG
PVVAITPFENDDEALALANNTKYGLAAYIWTQNLTRAHNFSQNVEAGMVWLNSHNVRDLRTPFGGVKASGLGHEGGYRSI
DFYTDQQAVHITLGTVHTPKFGSIEDSAANEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-101 49
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-71 42
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-70 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-72 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-72 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-72 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Asphe3_35000 YP_004242736.1 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase VFG0082 Protein 2e-70 41