Gene Information

Name : Asphe3_16730 (Asphe3_16730)
Accession : YP_004240968.1
Strain : Arthrobacter phenanthrenivorans Sphe3
Genome accession: NC_015145
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1791686 - 1793176 bp
Length : 1491 bp
Strand : +
Note : PFAM: pyruvate kinase, barrel domain; pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGAGACGCGCAAAAATTGTGGCTACGTTCGGCCCGGCAATTGCCAGCTACGAAAACACCCTCGCGGTGCTGGAAGCCGG
TGTTGACGTCGCCCGCATGAACATGAGCCACGGCGACTACTCCGTGCACGACAACACCTACGAGAACGTCCGCAAGGCGG
CAGCGGACCTCGGCAAGGCCGTGGCCATCATGGCCGACCTGCAGGGGCCGAAGATCCGCCTGGGCCGCTTCGTTGACGGA
CCGCACGCCCTCGCTGTAGGCGACACGTTCACCATCACCACCGAGGACGTGCCCGGCACCAAGGAGATCTGCTCCACCAC
GCTGAAGAGCCTCACCGAGGATGTCAACGTGGGCGATGCCCTGCTGATCGACGACGGCAAGGTGGCCCTGCGCGCCATCG
CTGTCGACGACGTGAAGGTTGTGGCCGAGGTGACCGTGGGCGGCATGGTGTCCAACAACAAGGGCATCAACCTGCCCGGC
GTGGCCGTCAACGTGCCCGCGCTGAGCGAAAAGGACGAGGACGACCTCCGCTGGGCCATGCGCCGCGGTGTCGACCTGGT
GGCACTGTCCTTCGTCCGGGATGCTTCGGACATTGTCCGCGTGCACGAGATCATGGACGAGGAAGGCCGCCGCGTGCCGG
TCATCGCCAAGATCGAGAAGCCGCAGGCCGTGGAGCAGTTGCCGGAGATCATCGACGCGTTCGACGCCATCATGGTGGCC
CGTGGCGACCTCGGCGTTGAGCTTCCGCTGGAGGAAGTGCCGATCGTCCAGAAGCGCGCCATCGAACTGGCCCGCCGCTG
GGCCAAGCCGGTCATCGTGGCCACCCAGGTGCTGGAATCCATGATCGACAACCCGCGCCCCACCCGCGCCGAGGCCTCCG
ACTGCGCCAACGCTGTGCTGGACGGTGCGGACGCCGTCATGCTTTCCGGTGAGACCAGCGTGGGCAAGTACCCGATCGAA
ACCGTCAAGGTCATGGCCCGGATCATCGAATCCACCGAGGTCCACGGCCTGGAGCGGGTCCCCCCGCTGGGGACCAAGCC
CAAGACCCGCGGCGGCGCCATCACCCGTGCCGCCGTCGAAATCGCCGACCAGCTGGACGCCAAGTACATCTGTGCTTTCA
CCCAGTCCGGCGACTCGGCCCGCCGCCTGTCCCGCCTGCGGCCCATCAAGCCGGTCTTCGCCTTCACTCCGGTGGAGCAG
GTCTGGAACCAGCTGGCGCTGACCTGGGGGATCCAGCCGGTGCTGGTGCAGATGGTGGACCACACCGATGAGATGACCGC
GCAGGTTGACCGCAGCCTGCTGGAGATGGACTTGGTGGATGACGGAGACCTGGTGGTTATTGCCGCCGGTTCGCCTCCCG
GAAAGGCCGGCTCCACGAACTCGCTGAAGGTGCACAAGGTGGGCGACCTCGCCGACTCCACCCGTGTTGGTGACGCCACC
AGCAACAAGGAAAAGCTCGGCCCCTGGCCGGAAAAGAAGAAGAAGGCCTAG

Protein sequence :
MRRAKIVATFGPAIASYENTLAVLEAGVDVARMNMSHGDYSVHDNTYENVRKAAADLGKAVAIMADLQGPKIRLGRFVDG
PHALAVGDTFTITTEDVPGTKEICSTTLKSLTEDVNVGDALLIDDGKVALRAIAVDDVKVVAEVTVGGMVSNNKGINLPG
VAVNVPALSEKDEDDLRWAMRRGVDLVALSFVRDASDIVRVHEIMDEEGRRVPVIAKIEKPQAVEQLPEIIDAFDAIMVA
RGDLGVELPLEEVPIVQKRAIELARRWAKPVIVATQVLESMIDNPRPTRAEASDCANAVLDGADAVMLSGETSVGKYPIE
TVKVMARIIESTEVHGLERVPPLGTKPKTRGGAITRAAVEIADQLDAKYICAFTQSGDSARRLSRLRPIKPVFAFTPVEQ
VWNQLALTWGIQPVLVQMVDHTDEMTAQVDRSLLEMDLVDDGDLVVIAAGSPPGKAGSTNSLKVHKVGDLADSTRVGDAT
SNKEKLGPWPEKKKKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-71 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-71 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-71 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-71 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Asphe3_16730 YP_004240968.1 pyruvate kinase VFG0479 Protein 5e-72 43