Gene Information

Name : Weevi_R0033 (Weevi_R0033)
Accession : YP_004238149.1
Strain : Weeksella virosa DSM 16922
Genome accession: NC_015144
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 901406 - 902908 bp
Length : 1503 bp
Strand : -
Note : COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: fjo:Fjoh_2967 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase domain; SPTR: aldehyde dehydrogenase (NAD(+)); tmRNA as predicted by Rfam (RF00023), score 167.23; PFAM: aldeh

DNA sequence :
ATGAGTTTAGTACAATTACCAGAACTTAAGCAGACTTACGACAACTACATTAACGGAAAATTTGTTGCGCCTGTCCAAGG
AAAATATTTCGATAACATTTCACCAGTTACAGGTAAGGTTTTTTCTAGAGCTGCTCATTCATCCAAAGAAGATATAGAGT
TCGCTGTAGATGCGGCTCACAAAGCTTTTGAGACTTGGAGCAAAACGTCTGCAGCTGAACGAAGTAGGATTCTAAATAAG
ATAGCTGATCGGATGGAAGAGAATCTAGAAAAAATAGCGGCAGTAGAAACGTATGATAATGGAAAACCCGTACGTGAAAC
TCTCAATGCAGATATTCCTTTAGCAATTGATCATTTCCGATATTTTGCAAGTGTAATTCGAGCAGAGGAAGGCTCATTGA
ATGAGTTGGATAAAAACACGGTCTCTCTTATTGTTAATGAGCCGATTGGTGTTGTGGCGCAAATTATACCGTGGAACTTT
CCAATCCTAATGGCAGTTTGGAAATTGGCTCCCGCTCTTGCTGCTGGATGCACAGTTGTATTAAAACCTGCAGAAAGTAC
TCCTGTCTCTATTATGTATCTATTCGAGTTGATTGGCGATTTGATTCCAGAAGGAGTCGTAAATATAGTAAATGGTTTTG
GATCCGAGTTAGGGCGTACCTTAGTTACCAATCCTAAAGTTGCCAAAGCTGCTTTTACAGGTTCAACCGCAACAGGTCGA
ATGGTGATGCAGTATGCAACCGAAAATATCATACCAGTTACATTAGAATTAGGTGGAAAATCTCCGAATATTTTCTTTGA
GTCGGTCATGGCAGAAGATGATGATTATCTTGATAAAGCACTGGAAGGTGCTGTGTTGTTTGCATTAAATCAGGGAGAAA
TCTGTACTTGTCCGTCGAGATTGTTGATACAAGAGTCCATTTACGATCGATTCATAGAAAAAGTAGTACAACGAACAGAA
GCCATTGTTACGGGAAATCCTCTAGATACAAATACAATGATAGGAGCACAAGCTTCGAAAATTCAATATGATAAAATTCT
TAATTATATCAAACTTGGTAAAGAAGAGGGAGCAGAATTATTAACCGGTGGTGAAGCCAACCCGTTAACAGGAGATATTG
CAGAAGGTTATTACATCAAACCCACCTTATTCAAAGGGGATAATAAAATGAGAATTTTCCAAGAAGAAATCTTCGGACCG
GTTTTGGCTGTTACAACCTTCAAGGATCAAGAAGATGCAATACGTATTGCTAATGATACTATTTATGGTTTGGGAGCGGG
TGTTTGGACTCGAGATGCGCATCAATTATATCAAGTTCCGCGTGCGATCCAGGCAGGTAGAGTATGGGTAAATCAATACC
ATAGTTATCCAGCAGGTGCTCCTTTTGGTGGGTACAAACAATCGGGTATCGGACGAGAAAATCACAAAATGATGTTAGAC
TATTATCGCCAAACCAAAAATATGTTGATTTCTTACGATAAAAAGAAATTAGGTTTTTTTTAA

Protein sequence :
MSLVQLPELKQTYDNYINGKFVAPVQGKYFDNISPVTGKVFSRAAHSSKEDIEFAVDAAHKAFETWSKTSAAERSRILNK
IADRMEENLEKIAAVETYDNGKPVRETLNADIPLAIDHFRYFASVIRAEEGSLNELDKNTVSLIVNEPIGVVAQIIPWNF
PILMAVWKLAPALAAGCTVVLKPAESTPVSIMYLFELIGDLIPEGVVNIVNGFGSELGRTLVTNPKVAKAAFTGSTATGR
MVMQYATENIIPVTLELGGKSPNIFFESVMAEDDDYLDKALEGAVLFALNQGEICTCPSRLLIQESIYDRFIEKVVQRTE
AIVTGNPLDTNTMIGAQASKIQYDKILNYIKLGKEEGAELLTGGEANPLTGDIAEGYYIKPTLFKGDNKMRIFQEEIFGP
VLAVTTFKDQEDAIRIANDTIYGLGAGVWTRDAHQLYQVPRAIQAGRVWVNQYHSYPAGAPFGGYKQSGIGRENHKMMLD
YYRQTKNMLISYDKKKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-146 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-150 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-150 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-150 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-149 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Weevi_R0033 YP_004238149.1 aldehyde dehydrogenase VFG0082 Protein 1e-146 63