Gene Information

Name : Weevi_0641 (Weevi_0641)
Accession : YP_004237936.1
Strain : Weeksella virosa DSM 16922
Genome accession: NC_015144
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 653409 - 653894 bp
Length : 486 bp
Strand : -
Note : COGs: COG0262 dihydrofolate reductase; InterPro IPR001796; KEGG: coc:Coch_0487 dihydrofolate reductase; PFAM: dihydrofolate reductase domain; PRIAM: dihydrofolate reductase; SPTR: dihydrofolate reductase; PFAM: dihydrofolate reductase

DNA sequence :
ATGCTACATCTCGTAGTCGCAATTGCAAGTAATCATGCGATAGGGAAGGGGAATCAGATGCTTTGGCATTTACCAAAAGA
TTTTCTACATTTCAAGAAAATCACTACCGGACATCCGATAATTATGGGTAGGAAAACATTCGAATCAATTGGTAGACCTT
TACCCAACCGAGTAAATATTGTGATTTCGCGAGACCGCAATTACTCTGCAGATGGAATACAGGTCGTTCATTCGTTGCGA
GAAGCTATAGAAAAAGGCTATAAGTTGGATGAGGATCTTTACGTGATTGGTGGTGGAGAAATTTATCGCCAAGCAATGGA
GTTTGCCGATAAAATCTATCTCACCGAAGTGCATCACGAATTTGAAGGGGATACATTTTTCCCAGAAATTGATGATGAAA
AATGGGTAGAAGTAGACCGTGAACATCATCTAAAAGATGATAAACATCTTTATAGTTATGATTTTGTAGAATATCTAAGA
AGATAA

Protein sequence :
MLHLVVAIASNHAIGKGNQMLWHLPKDFLHFKKITTGHPIIMGRKTFESIGRPLPNRVNIVISRDRNYSADGIQVVHSLR
EAIEKGYKLDEDLYVIGGGEIYRQAMEFADKIYLTEVHHEFEGDTFFPEIDDEKWVEVDREHHLKDDKHLYSYDFVEYLR
R

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 4e-29 44