Gene Information

Name : Weevi_1866 (Weevi_1866)
Accession : YP_004239132.1
Strain : Weeksella virosa DSM 16922
Genome accession: NC_015144
Putative virulence/resistance : Resistance
Product : beta-lactamase
Function : -
COG functional category : R : General function prediction only
COG ID : COG0491
EC number : -
Position : 1996830 - 1998224 bp
Length : 1395 bp
Strand : +
Note : COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279:IPR001763; KEGG: msv:Mesil_2631 rhodanese domain protein; PFAM: beta-lactamase-like; Rhodanese-like; SMART: beta-lactamase-like; Rhodanese-like; SPTR: metallo-beta-lactamase fam

DNA sequence :
ATGTTTTTCCAACACATTTACGAAAAATCTTTAGCTCATTCGAGTTATTTAATCGGGTGCCAAGTAGAAGGAACCGCAAT
GGTAATCGACCCGAAACGTGATATCGATACCTATTTAGAAATTGCTGCCGAGCAAAATCTCACCATAACCCATATTGCAG
AAACCCACATCCATGCCGATTATCTTTCGGGGAGTCTAGAGTTGGCACATGTTACTGGAGCAAAAATGTATCTTTCAGAC
GAGGGTGGATCAGATTGGCAATATTCTTTTGACCATATAGGGCTAAAAGATGGTGATGTGATAAAGTTAGGAAACCTATC
TTTCGAGGTGATGCATACCCCAGGACACACACCAGAAAGTTTGAGTTTCTTGCTCACCGATCATGCAGCAACTGAAGAGC
CAGTGATGTTATTTACAGGAGATTTTGTCTTTGTAGGCGATATCGGTCGCCCAGATTTATTAGAAGAAGCTGCCGGTTTG
GTTGGTACAAAAGAAGTTGGTGCACAGCAAATATTCGAGTCGTTGAAGAAGTTTTATGCACTTCCGGATCATATACAAGT
ATGGCCCGCACACGGCGCAGGCTCATCTTGTGGAAAAGCACTAGGAGCTGTCGCAAACTCCACTGTTGGATACGAAAAAA
TACAAAATTGGGCGTTTAAACTAAAAGAAAATAGAGAAGATTTCATTCAATATCTTTTGACAGATCAGCCCGAAGCGCCG
TATTATTTTGCGAAGATGAAACAATTGAACAAGCAATTGCGTCCGTTATTGGTAGAAGTTCCTAGAATCCCTCAACTCTC
CACTACAGACCTTACTTCTATACGTGCTCATAATCTAAAAATAATTGATACCCGATCGAAAACTGATTATGCCAAAGCTT
ATTTACCAGACACGATCAATATCCAAAATAATAAAAGCTTCAATACATGGATGGGTTGGATGTTGAATTACGAAGAGCAA
TTTGTTTTGATTGTACGAGAAGAAGATCTAGACGATGTTACCCGAAAATTAATGAGAATAGGCTTGGATAATGTGTATGG
TTATTACACACCAGAACAACTGTTTTGTGAAGGTTGTGAAGCAAAGACGACCAAAATTATAGATGTTTCAACCATCGAGT
CGTATATCGGGAAGGATGATATACAAATCTTAGACGTTAGAAGTCAAACGGAGTATACTGTAGGACATTTGCCAGGTGCC
AAACACATTTTTGTAGGACATTTACCACAGAAATGGCAAACGTTAGATCCTAAGAAAAAAATCGCATTGTATTGTCAATC
AGGTGATAGATCAACAATTGCGCAAAGTTTCTTATTGAAAAAAGGCTTCGATGTAGAAAACTATACAGAAGGTATGAGCC
AGTGGAAAACCTTGAATAAAATCATCGAACAATAA

Protein sequence :
MFFQHIYEKSLAHSSYLIGCQVEGTAMVIDPKRDIDTYLEIAAEQNLTITHIAETHIHADYLSGSLELAHVTGAKMYLSD
EGGSDWQYSFDHIGLKDGDVIKLGNLSFEVMHTPGHTPESLSFLLTDHAATEEPVMLFTGDFVFVGDIGRPDLLEEAAGL
VGTKEVGAQQIFESLKKFYALPDHIQVWPAHGAGSSCGKALGAVANSTVGYEKIQNWAFKLKENREDFIQYLLTDQPEAP
YYFAKMKQLNKQLRPLLVEVPRIPQLSTTDLTSIRAHNLKIIDTRSKTDYAKAYLPDTINIQNNKSFNTWMGWMLNYEEQ
FVLIVREEDLDDVTRKLMRIGLDNVYGYYTPEQLFCEGCEAKTTKIIDVSTIESYIGKDDIQILDVRSQTEYTVGHLPGA
KHIFVGHLPQKWQTLDPKKKIALYCQSGDRSTIAQSFLLKKGFDVENYTEGMSQWKTLNKIIEQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SACOL0046 YP_184956.1 metallo-beta-lactamase Not tested Type-I SCCmec Protein 5e-75 43
unnamed BAA86645.1 hypothetical protein Not tested Type-I SCCmec Protein 4e-75 43
unnamed BAB83478.1 - Not tested SCC 12263 Protein 3e-75 43