Gene Information

Name : Weevi_1152 (Weevi_1152)
Accession : YP_004238439.1
Strain : Weeksella virosa DSM 16922
Genome accession: NC_015144
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 1210410 - 1211561 bp
Length : 1152 bp
Strand : -
Note : COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: fjo:Fjoh_0710 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: cystathionine gamma-lyase; SPTR: cystathionine g

DNA sequence :
ATGAAATTCAATACAAAAACAATACACGGAGGACAACAACACGATCCTTCTACAGGAGCGGTGAATCCTCCTATTTATCA
GACCTCAACCTTTGCACAACAAAGTCCAGGAAAACACAAGGGATACGAATATGCACGTGGAGAAAACCCAACACGCACAG
CTCTAGAAAACTCTTTGGCTTCGATAGAAAGCGGTGTGGCCGGTTTTGCATTTGGTTCTGGACTGGCTGCAATTGATGGT
ATTTTGAAGTTATTTTCTCCAGGAGACGAAATCATCGCCATGGACGATTTGTATGGAGGTTCTTATCGATTATTCACACG
AGTTTATAGCAACTATGGCCTAAAATTCCATTTTGTGGATATGACCAATGTAGATGCGATTGTTGATTTGATGAACGACA
ACACCAAGATGATTTGGATAGAAACACCTACCAATCCTTTGATGAAAGTTGTGGATATTGAGGCTGTTTCGAAAGCTACA
AAAGCAAAAAACGCAAACGTTCTAGTGGCTGTAGACAACACTTTTGCATCGCCATATTTACAACGTCCAATCGAGTTGGG
CGCTGATATTGTTATGCATTCTGCGACCAAATATTTGGGCGGACATTCTGATTTGGTTGCTGGAGCTGTGATCGTAAATT
CGAAAGAATTAGCAGAAAAAGTTCATTTTAATTTATTCGCTACGGGCGGTATTTTAGGTCCACAAGATTCGTATTTAGTA
CTACGCGGGATAAAAACATTGGCCGTTCGCATGGATCGTCATTGCGAAAACGGAATGAAAATTGCCGAGTTTTTGGTTCA
ACATCCGAAAGTAGACAAAGTGTATTATCCGGGTCTAAGCAATCATCCACAGCACGAAATTGCCAAAAAACAAATGAAAG
CTTTTGGTGGAATGGTAACTTTCACATTAAAATCAGGTAAACAAGAAGATGCTTTTAAACTATTAGAGAACCTGAAAGTT
TTCACCTTAGCTGAGTCTTTGGGTGGCGTAGAATCTTTGGCCAATCATCCTGCAACGATGACACACGCATCGATCCCAGC
TGAAAAACGTGCTGAGATAGGAATCACAGATGATCTAATCCGCCTAAGTGTTGGTATTGAAGATATTGATGATTTGATTG
AAGATTTAACCAATGTTTTCGCGTTGATTTAA

Protein sequence :
MKFNTKTIHGGQQHDPSTGAVNPPIYQTSTFAQQSPGKHKGYEYARGENPTRTALENSLASIESGVAGFAFGSGLAAIDG
ILKLFSPGDEIIAMDDLYGGSYRLFTRVYSNYGLKFHFVDMTNVDAIVDLMNDNTKMIWIETPTNPLMKVVDIEAVSKAT
KAKNANVLVAVDNTFASPYLQRPIELGADIVMHSATKYLGGHSDLVAGAVIVNSKELAEKVHFNLFATGGILGPQDSYLV
LRGIKTLAVRMDRHCENGMKIAEFLVQHPKVDKVYYPGLSNHPQHEIAKKQMKAFGGMVTFTLKSGKQEDAFKLLENLKV
FTLAESLGGVESLANHPATMTHASIPAEKRAEIGITDDLIRLSVGIEDIDDLIEDLTNVFALI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-82 50
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-83 50
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-59 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Weevi_1152 YP_004238439.1 cystathionine gamma-synthase BAC0207 Protein 4e-75 44