Gene Information

Name : Weevi_1068 (Weevi_1068)
Accession : YP_004238355.1
Strain : Weeksella virosa DSM 16922
Genome accession: NC_015144
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1124929 - 1126368 bp
Length : 1440 bp
Strand : -
Note : COGs: COG0469 pyruvate kinase; InterPro IPR001697:IPR015793:IPR015795; KEGG: fba:FIC_02294 pyruvate kinase; PFAM: pyruvate kinase, barrel; pyruvate kinase, C-terminal-like; PRIAM: pyruvate kinase; SPTR: pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyr

DNA sequence : 
ATGAATGCAAACAAATACCTAAAAAAGACAAAAATTGTCGCAACTTTAGGACCAGCAACCGACTCGAAAGAAATTTTATT
AGACATGATGACCAAAGGTGTGGATGTTTTCCGCATCAACTTTTCGCATGCAGAATACGACGAAGTGAAAAAAAAGATAG
AAACCATACATCAACTCAACGATGAACATGGTTTCAACACTGCAGTATTAGCCGATTTACAAGGTCCTAAATTGCGAATC
GGGAAAATGGAGCACGAAGATTTTGTGATTAATCCGGGCGATATTTTGACGTTTACCAACGAAAAAGTAATCGGCAATGC
AGAAAAAGTATACATGACCTATCCCAAGTTTGCGCAAGATGTGCAGATAGGAGAAAATATTTTGATTGATGATGGAAAAT
TGATTTTTACGGTCATCGAAACCAACGGAGTGGATACTGTAAAAGCAAAAACAATCCAAGGTGGACCATTACGCTCTAAG
AAAGGTGTAAATCTTCCCAACACAAAAATTTCTTTACCTGCTCTGACAGAAAAAGACAAAGAAGATGCGCTTTTTGCTAT
CGAAAATAGAGTCGATTGGTTTGCTCTTTCGTTTGTTCGATCGGCACAAGATGTAGAAGATCTGAAAGCCTTTATCAGAG
AAAATTCGAATCTAAAAATTCCGATTATTAGTAAAATAGAAAAGCCAGAAGCACTCCAAAATATAGATGATATTCTGAAA
GTTTCTGATGGATTGATGGTTGCTCGTGGAGATTTGGGCGTTGAAGTTCCTTTTGAAGAAGTTCCTAGAGAACAAAAGCG
CTTGATAGACAAATCGAAATTGGCTCGTAAACCTGTTATTGTTGCTACCCAAATGATGGAATCTATGATTAGCAGCCTTA
CACCAACACGCGCAGAGGTAAGTGACGTAGCAAATGCTGTTTTTGATGGTGCTGATGCGGTAATGCTATCGGGCGAAACT
TCTGTTGGTAAATATCCTGTTCAGGTGATTGAGAAAATGACCAAAATACTTCAGACTGTAGAAGACGATGAACATATTAA
TATCCCAGAACATCAACCCAAAATCCAGAACGAACGCTTTGTAACAGACATCGTTTGTTACAATGCAGCAAAGATGGTAG
AACAAACCAATGCCAAAGTAATTGCAACCTTGACCTATTCGGGATACACGGCGTTCCAGATTTCCTCTCATCGTCCGTTA
TCGTATATTCTAGTGTTTAACCCTAGTAAGCGAATCAACCGAATGCTGAATTTACTTTGGGGTGTAAAAGCAATTAATTA
TGATCCACGAGATACAAGCACCGACCAAACAGTGATCGAAGTCAACACCATTGCTATTGAGCGTGGATTCGTAAAATATG
GCGAGTATATTATTAATCTAAATGCGATGCCAGCCTTCGAAAAAGGAATTACCAATACCGTTCGTTTAACGACTGCGTAA

Protein sequence : 
MNANKYLKKTKIVATLGPATDSKEILLDMMTKGVDVFRINFSHAEYDEVKKKIETIHQLNDEHGFNTAVLADLQGPKLRI
GKMEHEDFVINPGDILTFTNEKVIGNAEKVYMTYPKFAQDVQIGENILIDDGKLIFTVIETNGVDTVKAKTIQGGPLRSK
KGVNLPNTKISLPALTEKDKEDALFAIENRVDWFALSFVRSAQDVEDLKAFIRENSNLKIPIISKIEKPEALQNIDDILK
VSDGLMVARGDLGVEVPFEEVPREQKRLIDKSKLARKPVIVATQMMESMISSLTPTRAEVSDVANAVFDGADAVMLSGET
SVGKYPVQVIEKMTKILQTVEDDEHINIPEHQPKIQNERFVTDIVCYNAAKMVEQTNAKVIATLTYSGYTAFQISSHRPL
SYILVFNPSKRINRMLNLLWGVKAINYDPRDTSTDQTVIEVNTIAIERGFVKYGEYIINLNAMPAFEKGITNTVRLTTA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-66 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-66 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-66 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-66 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Weevi_1068 YP_004238355.1 pyruvate kinase VFG0479 Protein 1e-66 42