Gene Information

Name : Acav_3424 (Acav_3424)
Accession : YP_004235892.1
Strain : Acidovorax avenae ATCC 19860
Genome accession: NC_015138
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 3892960 - 3894678 bp
Length : 1719 bp
Strand : +
Note : TIGRFAM: Urease, alpha subunit; KEGG: vap:Vapar_4243 urease subunit alpha; PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal

DNA sequence :
ATGGCCACCGTATCCCGCCGCGCCTACGCGGAAATGTTCGGCCCCACCGTGGGCGACCGCGTGCGGCTGGCCGACACCGG
CCTCGTCGCCGAAGTCGAGCAGGACTTCACCCTGCGCGCCGGCGGCTACGGCGAGGAAGTCAAGTTCGGCGGCGGCAAGA
CCATCCGCGACGGCATGGCCCAGAGCCAGCGCACCCGCGCCGAAGGGGCGATGGACACCGTGCTCACCAACGCCCTCGTC
ATCGACCACTGGGGCATCGTCAAGGCCGATATCGGCCTGAAGGACGGCCGCGTCGCCGCCATCGGCAAGGCCGGCAACCC
GGACACCCAGCCCGGCGTGGACATCGTCATCGGCCCCGGCACCGAGATCATCAGCTGCGAAGGCAATATCGTCACCGCCG
GAGGCATCGACAGCCACATCCACTTCATCTGCCCCCAGCAGATCGAGGAGGCGCTGGCCTCCGGCGTCACCACCATGCTC
GGCGGCGGCACCGGCCCGGCCACCGGCACCCTGGCCACCACCTCCACCCCCGGCCCCTGGCACATCGAGCGCATGCTGCA
GGCGGCGGACGCCTTCCCGATGAACATCGGCTTCCTGGGCAAGGGCAACGCCAGCCTGCCCGCCGCGCTGCACGAGCAGA
TCGAGGCCGGCGTGATCGGCCTCAAGCTGCACGAGGACTGGGGCACCACGCCCTCGGCCATCAGCAACTGCCTGGACGTG
GCCGATGCCACCGACACGCAGGTGGCGATCCACTCCGACACCCTCAACGAGAGCGGCTTCGTCGAGAACACCATCGCCGC
CGTCGGCGGGCGCGGGATCTGCGCCTTCCACACCGAAGGCGCGGGCGGGGGCCATGCGCCGGACATCCTGCGCGTGGTGG
GCGAGGACAACTTCCTGCCCTCCTCCACCAACCCCACCATGCCCTACACGCGCAACACGCTGGACGAGCACGTGGACATG
CTCATGGTGTGCCACCACCTGGACGCCTCCATCGCCGAAGACCTGGCCTTCGCCGAGAGCCGCATCCGCAAGGAAACCAT
CGCCGCCGAGGACATCCTGCACGACCTGGGCGCCATCAGCATGATGAGCAGCGACAGCCAGGCCATGGGCCGCGTCGGCG
AAGTCATCCTGCGCACCTGGCAGACGGCCGACAAGATGAAGCAGCAGCGCGGCGCCCTGCCCGAGGATGGCCCCCGCAAC
GACAACCACCGCATCAAGCGCTACGTCGCCAAGTACACCATCAACCCCGCGATCGCCCACGGCATTTCCCACGACGTGGG
CAGCCTGGAGGTCGGCAAGTGGGCCGACATCGTGGTCTGGAAGCCCGCCTTCTTCGGCGTGAAGCCCGCGATGATCCTCA
AGGGCGGCAGCATCGCCCTGGCCGCCATGGGCGACCCCAACGCCTCCATCCCCACGCCCCAGCCCGTGCACTACCGCCCC
ATGTTCGGTGCCTTCGGCGGCTCCCTGGAGCGCTCCTCGCTCACCTTCGTCTCGCAGGCGGCCATGGCGGCCGGCGTGGG
CGAGCGCTACGGCCTGGCCAAGCAGCTCAGCGCCGTGCGCGGCATCCGCGGCGTGCGCAAGCAGCACATGGTGCACAACA
GCTACACCCCGCGCATGGAGATCGACGCGCAGACCTACACCGTGCGCGCCGACGGCCAGCTGCTCACCTGCGAACCCGCC
ACCCGGCTGCCGCTGGCGCAGCGCTACTTCCTTTTCTGA

Protein sequence :
MATVSRRAYAEMFGPTVGDRVRLADTGLVAEVEQDFTLRAGGYGEEVKFGGGKTIRDGMAQSQRTRAEGAMDTVLTNALV
IDHWGIVKADIGLKDGRVAAIGKAGNPDTQPGVDIVIGPGTEIISCEGNIVTAGGIDSHIHFICPQQIEEALASGVTTML
GGGTGPATGTLATTSTPGPWHIERMLQAADAFPMNIGFLGKGNASLPAALHEQIEAGVIGLKLHEDWGTTPSAISNCLDV
ADATDTQVAIHSDTLNESGFVENTIAAVGGRGICAFHTEGAGGGHAPDILRVVGEDNFLPSSTNPTMPYTRNTLDEHVDM
LMVCHHLDASIAEDLAFAESRIRKETIAAEDILHDLGAISMMSSDSQAMGRVGEVILRTWQTADKMKQQRGALPEDGPRN
DNHRIKRYVAKYTINPAIAHGISHDVGSLEVGKWADIVVWKPAFFGVKPAMILKGGSIALAAMGDPNASIPTPQPVHYRP
MFGAFGGSLERSSLTFVSQAAMAAGVGERYGLAKQLSAVRGIRGVRKQHMVHNSYTPRMEIDAQTYTVRADGQLLTCEPA
TRLPLAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-169 69
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-169 69
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-150 60
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-150 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-150 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-150 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acav_3424 YP_004235892.1 urease subunit alpha VFG0270 Protein 2e-143 61