Gene Information

Name : ureC (BSn5_09260)
Accession : YP_004205499.1
Strain : Bacillus subtilis BSn5
Genome accession: NC_014976
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1768062 - 1769771 bp
Length : 1710 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAATGTCACGGGAGGAATATGCGGAACTGTTTGGCCCGACAACGGGCGATAAAATCAGATTGGGCGACACGGATTT
ATGGATCGAAGTCGAAAGGGATTTCACAGTATATGGTGAAGAAATGATCTTTGGCGGCGGAAAAACTATCCGCGACGGCA
TGGGCCAAAACGGCAGAATCACAGGGAAGGACGGCGCTTTGGATTTGGTTATCACCAACGTCGTGCTATTGGATTACACA
GGCATTGTCAAAGCGGATGTCGGTGTGAAAGACGGCCGGATTGTCGGTGTCGGAAAAAGCGGAAATCCTGATATCATGGA
TGGAGTCGATCCGCACATGGTCATAGGAGCGGGGACAGAGGTGATTTCCGGTGAAGGCAAAATTTTAACAGCCGGGGGAG
TGGACACGCACATTCATTTTATTTGTCCTCAGCAGATGGAAGTTGCGCTTTCTTCAGGTGTGACAACCCTTTTGGGAGGC
GGAACAGGACCCGCTACAGGAAGCAAAGCGACAACATGTACATCCGGCGCGTGGTATATGGCAAGGATGCTGGAAGCAGC
CGAGGAGTTTCCGATCAATGTCGGCTTCTTAGGGAAAGGGAATGCATCCGATAAAGCGCCGCTGATCGAGCAGGTGGAAG
CAGGCGCCATCGGCCTTAAGCTTCATGAAGACTGGGGCACGACGCCAAGCGCCATTAAAACGTGTATGGAAGTCGTGGAC
GAGACTGATATTCAAGTTGCCATCCATACCGATACGATTAACGAAGCGGGCTTTTTGGAAAACACGCTCGACGCAATCGG
GGACCGGGTCATTCATACTTATCACATTGAAGGTGCAGGCGGCGGCCATGCCCCGGATATTATGAAGCTCGCCTCTTACG
CGAACATTCTGCCGTCATCTACAACGCCAACCATTCCTTATACCGTTAATACGATGGATGAGCATCTTGACATGATGATG
GTCTGCCACCATTTAGATGCGAAAGTGCCTGAAGATGTGGCGTTCAGCCATTCCAGAATCAGGGCTGCGACGATTGCCGC
GGAGGATATTCTCCATGATATCGGTGCGATCAGCATGACATCATCGGATTCCCAAGCGATGGGGCGGGTCGGTGAAGTGA
TCATCCGAACATGGCAGGTAGCCGATAAAATGAAAAAACAGCGCGGCGCTCTTGCCGGCGAAAACGGAAATGACAATGTG
CGCGCAAAACGGTACATTGCCAAATACACGATTAATCCGGCAATTACGCACGGGCTCAGCCATGAAGTCGGCTCGGTGGA
AAAAGGGAAGCTTGCTGATCTCGTTCTGTGGGACCCGGTATTTTTCGGCGTAAAACCGGAACTGGTCTTAAAGGGCGGCA
TGATTGCACGTGCGCAAATGGGAGATCCGAACGCGTCCATCCCGACTCCTGAACCGGTTTTCATGCGCCAAATGTATGCG
TCTTACGGAAAAGCCAATCGCTCAACCTCGATTACATTTATGTCTCAGGCAAGCATAGAGCGTGGTGTGGCGGAAAGCTT
AGGGCTGGAAAAAAGGATTTCTCCAGTCAAAAATATCAGAAAGCTGAGCAAGCTGGATATGAAGCTGAATTCGGCTTTGC
CGAAGATTGAGATTGATCCAAAAACCTATCAGGTCTTTGCTGACGGGGAGGAATTGTCTTGCCAGCCTGTCGATTATGTC
CCACTTGGACAAAGATATTTCTTATTTTGA

Protein sequence :
MKMSREEYAELFGPTTGDKIRLGDTDLWIEVERDFTVYGEEMIFGGGKTIRDGMGQNGRITGKDGALDLVITNVVLLDYT
GIVKADVGVKDGRIVGVGKSGNPDIMDGVDPHMVIGAGTEVISGEGKILTAGGVDTHIHFICPQQMEVALSSGVTTLLGG
GTGPATGSKATTCTSGAWYMARMLEAAEEFPINVGFLGKGNASDKAPLIEQVEAGAIGLKLHEDWGTTPSAIKTCMEVVD
ETDIQVAIHTDTINEAGFLENTLDAIGDRVIHTYHIEGAGGGHAPDIMKLASYANILPSSTTPTIPYTVNTMDEHLDMMM
VCHHLDAKVPEDVAFSHSRIRAATIAAEDILHDIGAISMTSSDSQAMGRVGEVIIRTWQVADKMKKQRGALAGENGNDNV
RAKRYIAKYTINPAITHGLSHEVGSVEKGKLADLVLWDPVFFGVKPELVLKGGMIARAQMGDPNASIPTPEPVFMRQMYA
SYGKANRSTSITFMSQASIERGVAESLGLEKRISPVKNIRKLSKLDMKLNSALPKIEIDPKTYQVFADGEELSCQPVDYV
PLGQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 4e-172 64
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 4e-172 64
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-167 61
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-167 61
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 5e-167 61
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-167 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_004205499.1 urease subunit alpha VFG0270 Protein 1e-157 62