Gene Information

Name : BSn5_06880 (BSn5_06880)
Accession : YP_004205029.1
Strain : Bacillus subtilis BSn5
Genome accession: NC_014976
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 1296238 - 1297857 bp
Length : 1620 bp
Strand : -
Note : COG1021 Peptide arylation enzymes

DNA sequence : 
ATGCTGAAAGGATTTACGCCTTGGCCTGATGAGTTAGCTAAGACCTATCGAAAGAACGGCTGCTGGGCCGGTGAGACGTT
TGGAGATTTGTTAAGGGACCGGGCAGCCAAATATGGTGATCGCATTGCCATTACATGCGGAAACACCCATTGGAGCTATC
GAGAGCTTGACACAAGAGCTGATCGCCTGGCTGCCGGATTTCAAAAGCTCGGCATTCAACAGATGGATCGTGTTGTGGTG
CAGCTGCCAAATATCAAAGAGTTTTTTGAAGTCATTTTCGCGCTTTTCCGTCTGGGGGCGCTTCCAGTCTTCGCACTGCC
TTCTCATCGAAGCAGTGAAATTACATATTTTTGCGAGTTTGCTGAAGCGGCTGCATATATCATTCCCGACGCTTATTCCG
GTTTTGACTACCGTTCGCTTGCCAGACAGGTTCAAAGCAAGCTGCCGACTTTGAAAAACATCATTGTCGCAGGTGAGGCA
GAGGAATTTTTGCCGCTGGAGGATTTGCATGCAGAACCTGTAAAACTGCCTGAAGTCAAATCTTCGGATGTGGCGTTCCT
CCAGCTTTCTGGCGGGAGCACCGGGCTATCGAAACTGATTCCGAGGACCCACGATGACTACATATACAGCCTGAAGCGGA
GTGTGGAGGTCTGCTGGCTCGACCACAGCACGGTGTACTTGGCCGCGCTGCCGATGGCACACAATTATCCGCTGAGCTCA
CCCGGCGTTCTCGGCGTATTATACGCTGGAGGAAGAGTGGTATTATCTCCTTCTCCAAGTCCAGATGACGCATTTCCTTT
AATTGAACGGGAAAAGGTCACGATAACCGCTCTTGTTCCGCCTCTTGCGATGGTATGGATGGATGCGGCATCCTCACGCC
GTGATGATTTATCCAGCCTTCAAGTGCTGCAGGTCGGCGGTGCCAAGTTTAGTGCTGAAGCCGCGCGCAGGGTAAAAGCT
GTTTTCGGCTGCACGCTGCAGCAGGTGTTCGGAATGGCAGAGGGTCTCGTCAATTATACGAGATTGGATGATCCTGAGGA
GATCATTGTCAACACCCAAGGAAAACCGATGTCTCCATATGATGAAGTGCGTGTTTGGGATGATCATGATCGCGACGTAA
AACCTGGTGAAACAGGCCATCTGCTGACGCGGGGACCGTATACAATTCGAGGTTACTATAAGGCGGAAGAGCATAATGCC
GCTTCATTTACTGAGGATGGTTTTTACCGTACGGGTGATATCGTCAGGCTGACACGAGACGGCTATATTGTCGTTGAAGG
CCGGGCGAAGGATCAAATTAACCGTGGAGGAGAAAAGGTTGCGGCTGAAGAGGTAGAAAATCATCTGCTGGCGCATCCGG
CTGTCCATGATGCGGCAATGGTCTCCATGCCTGATCAATTTCTTGGCGAAAGATCTTGTGTGTTCATTATTCCCCGGGAT
GAAGCCCCAAAAGCCGCAGAGCTCAAAGCATTTTTGAGAGAGCGCGGACTGGCGGCATATAAAATCCCTGATCGAGTTGA
ATTTGTCGAATCCTTCCCGCAGACAGGAGTAGGAAAAGTCAGCAAAAAAGCGCTCCGTGAAGCCATTTCCGAGAAGCTTC
TTGCAGGATTAAAAAAATAA

Protein sequence : 
MLKGFTPWPDELAKTYRKNGCWAGETFGDLLRDRAAKYGDRIAITCGNTHWSYRELDTRADRLAAGFQKLGIQQMDRVVV
QLPNIKEFFEVIFALFRLGALPVFALPSHRSSEITYFCEFAEAAAYIIPDAYSGFDYRSLARQVQSKLPTLKNIIVAGEA
EEFLPLEDLHAEPVKLPEVKSSDVAFLQLSGGSTGLSKLIPRTHDDYIYSLKRSVEVCWLDHSTVYLAALPMAHNYPLSS
PGVLGVLYAGGRVVLSPSPSPDDAFPLIEREKVTITALVPPLAMVWMDAASSRRDDLSSLQVLQVGGAKFSAEAARRVKA
VFGCTLQQVFGMAEGLVNYTRLDDPEEIIVNTQGKPMSPYDEVRVWDDHDRDVKPGETGHLLTRGPYTIRGYYKAEEHNA
ASFTEDGFYRTGDIVRLTRDGYIVVEGRAKDQINRGGEKVAAEEVENHLLAHPAVHDAAMVSMPDQFLGERSCVFIIPRD
EAPKAAELKAFLRERGLAAYKIPDRVEFVESFPQTGVGKVSKKALREAISEKLLAGLKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-116 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-116 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-116 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-116 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-116 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-116 50
ybtE CAA21394.1 - Virulence HPI Protein 2e-116 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-116 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-116 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BSn5_06880 YP_004205029.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-135 55
BSn5_06880 YP_004205029.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 4e-111 48
BSn5_06880 YP_004205029.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-111 45