Gene Information

Name : pyk (TSC_c00040)
Accession : YP_004201206.1
Strain : Thermus scotoductus SA-01
Genome accession: NC_014974
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 4089 - 5513 bp
Length : 1425 bp
Strand : +
Note : -

DNA sequence : 
ATGAGGCCTTTTAAGCGCACCAAGATTGTGGCCACCCTGGGGCCCGCTTCGGACTCCAAGGAAGCCATCCGGGCCCTGGC
GGAGGCAGGGGCGGATGTCTTTCGCCTGAACTTTAGCCACGGCACCCACGAGGAGCACCGCAGGCGGGCGGCCTGGGTGC
GGGAGGTGGAGAAGGAACTGGGCAAAACCCTGGCCATCCTCCAGGACCTCCAGGGCCCCAAGATCCGCATAGGCCGCTTC
AAGGAGGGCCGGGTGGAGCTTAAGGCCGGCCAGCCCTTTATCCTCACCCGGGCTCCCGTGGAGGGGGACGAGACCCGGGT
TTCCATCACCTACAAGGGGCTTCCCGAGGACGTGGCTCCCGGTCAGGTGCTCCTCTTGGACGACGGCCGCCTGCGCCTTC
GGGTGGAGAGGATCCAAGGGGACGAGATCCACACCGTGGTGGAGCTGGGTGGGATTCTTTCCGACAGTAAGGGGATCAAC
GTCCCTGGCTCGGATCTTTCCATCCCCGCTCTCTCGGAAAAGGACATCCAGGACCTAGCCCTGGGGGCGGAGCTCGGGGT
GGACTGGGTGGCGGTTTCCTTCGTGCGCACCCGGGATGACCTGCTCCTGGCCCGGCACTACCTGGCCCGGCATGGTTCCC
GGGCCCGGCTCATGGCCAAGATAGAGAAGCCTTCCGCCGTCTACCGCTTTGAGGAGATCCTGGAAGAGGCCGACGGCATC
ATGGTGGCCCGGGGGGACCTGGGGGTGGAGATGCCTCTGGAGGAGGTGCCCATCATGCAAAAGCGCCTTATCCTCAAGGC
CATTGCCGCCGGGAAACCGGTGATCACCGCCACCCAGATGCTGGAGTCCATGGTGCAGAACCCAAGCCCCACCCGGGCAG
AGGCCTCGGATGTGGCCAACGCCATCTTCGACGGCACGGATGCGGTGATGCTTTCCGCGGAAACCGCTGCCGGGGCCTAT
CCGGTGGAGGCCGTGGCCACCATGGCCAGGATCGCCCGGGTGGTGGAGTCCTCCCCCGAGTTCTTGCAAAAGCTCAATGT
CCTCCGCCCGGCTCCCACCCCCACCACCCAGGACGCCATCGCCCAGGCGGCGGACGACATCGTGGAGGCAGTGGACGCCA
GGGCCATCGTGGTCTTCACCGCCACGGGGAGTTCCGCCAGGCGTATTGCCCGCACGCGGCCCAAAGTGCCCATCCTGGCC
CTCACCCCGAACCCCGAGGTGGAGCGGCAGCTGGCCTTGGTCTGGGGTGTTCTGCCCCATCTGGCCCCCGACCCCCAGGA
CACCGACGACATGGTGCGCATCGCCCTGGAGAAGGCCAAGGCCTGCGGGCTGGCCCAGGTGGGGGAGAGGGTGGTGATCG
CCGCGGGAGTGCCCTTTGGGGTGCGGGGGACCACCAACCTCATCCGGGTGGAGCGGGTGAGCTAA

Protein sequence : 
MRPFKRTKIVATLGPASDSKEAIRALAEAGADVFRLNFSHGTHEEHRRRAAWVREVEKELGKTLAILQDLQGPKIRIGRF
KEGRVELKAGQPFILTRAPVEGDETRVSITYKGLPEDVAPGQVLLLDDGRLRLRVERIQGDEIHTVVELGGILSDSKGIN
VPGSDLSIPALSEKDIQDLALGAELGVDWVAVSFVRTRDDLLLARHYLARHGSRARLMAKIEKPSAVYRFEEILEEADGI
MVARGDLGVEMPLEEVPIMQKRLILKAIAAGKPVITATQMLESMVQNPSPTRAEASDVANAIFDGTDAVMLSAETAAGAY
PVEAVATMARIARVVESSPEFLQKLNVLRPAPTPTTQDAIAQAADDIVEAVDARAIVVFTATGSSARRIARTRPKVPILA
LTPNPEVERQLALVWGVLPHLAPDPQDTDDMVRIALEKAKACGLAQVGERVVIAAGVPFGVRGTTNLIRVERVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-75 45
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-75 45
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-75 45
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-75 45
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 4e-60 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_004201206.1 pyruvate kinase VFG0479 Protein 2e-75 45