Gene Information

Name : clpB (TSC_c20310)
Accession : YP_004203186.1
Strain : Thermus scotoductus SA-01
Genome accession: NC_014974
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone protein ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1924987 - 1927572 bp
Length : 2586 bp
Strand : +
Note : -

DNA sequence :
ATGAACCTGGAACGCTGGACCCAAGCCGCCCGCGAGGCCCTGGCCCAGGCCCAGGTCCTGGCCCGGGAGATGAAGCACCA
GGCCATCGACCTGCCCCATCTCTGGGCTGTGCTGCTTAAGGACCCCACGGGCCTGGCCTGGCGGCTTCTGGAGAGGGCAG
GGGGTAACCCCAAGGCCCTTAAGGAAAGCGCCGAGCGGGAACTGGGCCGCCTGCCCAAGGTGGAGGGGGCCGAGGTGGGC
CAGTACCTTTCCCAAAGGCTTGCCCGGGCCCTGGACCGGGCCGAGGCCCTCATGGGGGAGCTTAAGGACCGGTTCGTGGC
CTTGGACACCCTGGTCCTGGCCTTGGCGGAGGCCTCGAGGGCCGAGCCCTCCTTCCAGGTGGGTATTCCCGAAGAAGGCT
CCTTAAGAAAAGCCCTACAGGAACTAAGAGGAGGTAAAACCGTGCAGACGGAACATGCGGAAAGCACCTACAACGCCCTG
GAGCAGTACGGCATCGACCTCACCAAGCTGGCCGCCGAGGGCAAGCTGGACCCAGTGATCGGCCGGGACGAGGAGATAAG
GCGCACCATCCAGATCCTCCTCCGGCGCACCAAGAACAACCCGGTGCTCATCGGCGAACCGGGGGTGGGTAAGACCGCCA
TCGTGGAGGGGCTGGCCCAGCGCATCGTCAAGGGGGATGTGCCGGAAGGCCTCAAGGGCAAGCGCATCATCTCCTTGCAG
ATGGGCTCCCTCCTGGCCGGGGCCAAGTACCGGGGCGAGTTTGAGGAGCGCCTGAAGGCGGTGATCCAGGAGGTGGTGCA
AAGCCAGGGGGAAATCATCCTCTTCATCGACGAGCTCCACACCGTGGTGGGGGCGGGCAAGGCCGAGGGGGCCGTGGACG
CCGGCAACATGCTGAAGCCCGCCCTGGCCCGGGGGGAGCTTCGGCTTATCGGCGCCACCACCCTGGACGAGTACCGGGAG
ATCGAGAAGGACCCCGCCCTGGAAAGGCGCTTCCAGCCCGTCTTCGTGGACGAGCCCAGCGTGGAGGAGACCATCTCCAT
CCTCCGGGGCATCAAGGAGAAGTACGAGGTGCACCATGGGGTCAGGATCTCCGACCCCGCCCTGGTGGCGGCGGCGGTCC
TCTCCCACCGCTACATCACGGAAAGGCGCCTTCCCGACAAGGCCATCGACCTCATCGACGAGGCGGCAGCCCGCCTGCGC
ATGGCCTTGGAAAGCGCCCCTGAGGAGATCGACACCTTGGAGCGGAAGAAGCTCCAGCTGGAGATCGAACGGGAGGCCCT
AAAGAAGGAGAAGGACCCGGACTCCCAGGAGAGGCTCAAGGCCATCGAGGAGGAGATCGCCCACCTCAACCAGGAGATCC
AGAAGCTCAAGGCCGAGTGGGAGGCAGAGCGGGAGGTCCTGAAGAAGCTGCGGGAGGCCCAGCAACGCCTGGACGAGGTC
CGGCGGCAGATCGAGCTGGCGGAGCGCCAGTACGACCTGAACCGGGCCGCCGAGCTCCGCTACGGGGAGCTTCCCCGCCT
CGAGGCCGAGGTGGAGGCCCTCTCCGAGAAGCTCAAAAACGCCCGCTTCGTACGCCTGGAGGTGACCGAGGAGGACATCG
CCGAGATCGTCTCCCGCTGGACGGGCATCCCGGTTTCCAAGCTCCTGGAAGGGGAAAGGGAGAAGCTCTTACGGCTTGAG
GACGAGCTCCACAAGCGGGTGGTGGGGCAGGAGGAGGCCATCCGGGCCGTGGCCGACGCCATAAGGCGGGCCCGGGCCGG
CCTCAAGGACCCGAACCGCCCCATCGGAAGCTTCCTTTTCCTGGGCCCCACGGGGGTGGGCAAGACGGAGCTGGCCAAGA
CCCTGGCCGCCACCCTCTTCGACACCGAGGAGGCCATGGTGCGCATCGACATGACGGAGTACATGGAGAAGCACGCGGTG
AGCCGGCTCATCGGGGCGCCACCCGGCTACGTGGGCTACGAGGAAGGTGGGCAGCTCACCGAGGCGGTGAGGCGCCGCCC
CTACACGGTCATCCTCTTCGACGAGATCGAGAAGGCCCACCCCGATGTCTTCAACATCCTCCTGCAGATCCTGGACGACG
GCCGCCTCACCGACTCCCACGGGCGCACCGTGGACTTCCGCAACACGGTGATCATCCTCACCTCCAACCTGGGAAGCCCC
CTGATCCTCGAGGGCATCCAGAAGGGCCTGCCCTACGAGCGCATCCGGGAGGAGGTCTTCGCCGTGTTGCAAAAGCACTT
CCGCCCCGAGTTCCTGAACCGCCTGGACGAGATCGTGGTCTTCAGGCCCCTCACCCGGGAGCAGCTGCGGGAGATCGTGG
AGATCCAGCTCCAAAGCCTCAGGGCCCGCCTGGCGGAAAAGCGCATCACCCTTACCCTCACCGAGGCCGCCAAGGACTAC
CTGGCCGAGCGGGGCTACGACCCCGTCTTCGGGGCCAGGCCCCTGAAGCGGGTGATCGCCCGGGAGCTGGAAACCCCCCT
GGCGGTGAAGATCCTGGCCGGGGAGATCAAGGAGGGGGATGCCGTGGTGGTGGACGCCGGGCCCACGGGGCTGGTCTTCC
GCACCCCCGAGCGGGTAGAGGCCTGA

Protein sequence :
MNLERWTQAAREALAQAQVLAREMKHQAIDLPHLWAVLLKDPTGLAWRLLERAGGNPKALKESAERELGRLPKVEGAEVG
QYLSQRLARALDRAEALMGELKDRFVALDTLVLALAEASRAEPSFQVGIPEEGSLRKALQELRGGKTVQTEHAESTYNAL
EQYGIDLTKLAAEGKLDPVIGRDEEIRRTIQILLRRTKNNPVLIGEPGVGKTAIVEGLAQRIVKGDVPEGLKGKRIISLQ
MGSLLAGAKYRGEFEERLKAVIQEVVQSQGEIILFIDELHTVVGAGKAEGAVDAGNMLKPALARGELRLIGATTLDEYRE
IEKDPALERRFQPVFVDEPSVEETISILRGIKEKYEVHHGVRISDPALVAAAVLSHRYITERRLPDKAIDLIDEAAARLR
MALESAPEEIDTLERKKLQLEIEREALKKEKDPDSQERLKAIEEEIAHLNQEIQKLKAEWEAEREVLKKLREAQQRLDEV
RRQIELAERQYDLNRAAELRYGELPRLEAEVEALSEKLKNARFVRLEVTEEDIAEIVSRWTGIPVSKLLEGEREKLLRLE
DELHKRVVGQEEAIRAVADAIRRARAGLKDPNRPIGSFLFLGPTGVGKTELAKTLAATLFDTEEAMVRIDMTEYMEKHAV
SRLIGAPPGYVGYEEGGQLTEAVRRRPYTVILFDEIEKAHPDVFNILLQILDDGRLTDSHGRTVDFRNTVIILTSNLGSP
LILEGIQKGLPYERIREEVFAVLQKHFRPEFLNRLDEIVVFRPLTREQLREIVEIQLQSLRARLAEKRITLTLTEAAKDY
LAERGYDPVFGARPLKRVIARELETPLAVKILAGEIKEGDAVVVDAGPTGLVFRTPERVEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 4e-91 44
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 5e-95 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-95 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_004203186.1 ATP-dependent chaperone protein ClpB VFG2076 Protein 3e-103 44