Gene Information

Name : TSC_c16730 (TSC_c16730)
Accession : YP_004202837.1
Strain : Thermus scotoductus SA-01
Genome accession: NC_014974
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 1591600 - 1593081 bp
Length : 1482 bp
Strand : +
Note : aldh-e2; aldhi; ahd-m1; aldhclass 2

DNA sequence : 
ATGCGTCTTCCCCTGCCGGAAAAGGCCGAGGCCTTCTTAAAGCGGGTAGGCCCCCTTTACCTAGGGGGAACTTTCCGGAA
GGCCGCAACAGGGGAGGTTTTTCCTGTTTTGAACCCAGCCACGGGGGAAGTCTTGGCCCGGGTGGCCCGGGGCGGCAAGG
AGGACGTGGACCAGGCGGTGGCCCTGGCTCGGAAGGCCTTGGAGGGAAGCTGGGGCCGCACGAGCCCCGATGAGCGGGGC
CGGCTTCTCTTTCGCCTAAGCGAGCTCATTGAGGCGCACGCGGACACCCTGGCCGCCCTCGAGGCCTTGAACGTGGGCAA
ACCCTATGCGGAGGCCCGCACTGCCGATATCCCTCTGGTAGCCCAGCACTTCCGTTACTTCGCGGGCTGGGCCACCAAGT
GGGGGGGCGAGGTCCTGCCCGTCTCCTTCCCCGGGGAATACCTGGCCTATACCCGGCGGGAACCCGTGGGGGTGGTAGGG
GCCATCACCCCTTGGAACTTTCCTCTCCTCATCGCGAGCTGGAAGCTTGCCCCGGCTTTGGCCGTGGGTTGCACGGTTAT
CCTCAAACCCTCGGAACTCACCCCCCTCACCGCCCTCTACTTGGCCGAGCTCATGGAAGAGGCTGGTTTCCCCAAGGGTA
CGGTAAGCGTGATTCCCGGGTATGGGGAAGAAGCGGGGGCGGCCTTGGTAGCCCACCCCGGGGTGGACAAGATCTCCTTC
ACGGGCTCGGTGGAGGTGGGCAAGGGCATCCTCAAGCAGGCGGCGGAAACCCTAAAAAGGGTGACCCTGGAACTCGGGGG
TAAGTCTCCGGTCATCCTCCTAGAGGACGCCGACCCCAAGCGGGTCCTCAAGGGAGCTCTCTTCGCAAGTTTCTTCAACC
AAGGCGAGGTGTGTGCTGCGGGAAGCCGCCTTTTCGTGCCCAAAAGTAAGTTAGATTACTTCTTAGAAAACCTGGTAACG
GGCGCGCAGGCCATCCAGCAAGGCCATCCCTTGGACCCCAGGACGCAGATGGGGCCGCTCATTAGCCGGGAACACATGGA
GCGGGTTTTAGGCTATGTCCAAAGGGGGCTGGAGGAGGGGGCCACCCTGCTCACGGGTGGGGAGCCAAATCCCGGGGCAG
GCCCGGGTTTCTTTGTAAAACCAACGATCTTCCTAGCTGAGGATGGGCAGACCATCGCCCGGGAAGAAATCTTCGGACCC
GTCCTCAGCGTCCTCCCCTATGAAGACCCGGAGGAGGTGGCTCGGCGGGCCAACGCTACTCCCTACGGCCTCGCCGCGGG
AATCTTCGGCCAGGACATGAGGCGGGCTATTCGGCTGGCCCATGCCTTAAAGGCGGGTACGGTCTGGATCAACGGCTACC
TCCTCCTGGATGCGGCAAGTCCCTGGGGTGGGTACAAGGAAAGTGGCATAGGTCGGGAGATGGGCCGGTATGCCTTAGAG
CACTACACCGAGGTCAAGAGTGTGTGGCTCAACCTAACTTGA

Protein sequence : 
MRLPLPEKAEAFLKRVGPLYLGGTFRKAATGEVFPVLNPATGEVLARVARGGKEDVDQAVALARKALEGSWGRTSPDERG
RLLFRLSELIEAHADTLAALEALNVGKPYAEARTADIPLVAQHFRYFAGWATKWGGEVLPVSFPGEYLAYTRREPVGVVG
AITPWNFPLLIASWKLAPALAVGCTVILKPSELTPLTALYLAELMEEAGFPKGTVSVIPGYGEEAGAALVAHPGVDKISF
TGSVEVGKGILKQAAETLKRVTLELGGKSPVILLEDADPKRVLKGALFASFFNQGEVCAAGSRLFVPKSKLDYFLENLVT
GAQAIQQGHPLDPRTQMGPLISREHMERVLGYVQRGLEEGATLLTGGEPNPGAGPGFFVKPTIFLAEDGQTIAREEIFGP
VLSVLPYEDPEEVARRANATPYGLAAGIFGQDMRRAIRLAHALKAGTVWINGYLLLDAASPWGGYKESGIGREMGRYALE
HYTEVKSVWLNLT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 9e-66 45
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 4e-66 45
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 2e-64 45
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 2e-65 45
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 9e-66 45
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 9e-66 45
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-89 45
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-90 45
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-90 45
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-90 45
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-75 45
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-90 45
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 2e-65 44
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 2e-65 44
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 2e-65 44
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-78 44
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 1e-82 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TSC_c16730 YP_004202837.1 aldehyde dehydrogenase VFG0082 Protein 4e-89 45