Gene Information

Name : folP (TSC_c00130)
Accession : YP_004201215.1
Strain : Thermus scotoductus SA-01
Genome accession: NC_014974
Putative virulence/resistance : Resistance
Product : dihydropteroate synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0294
EC number : 2.5.1.15
Position : 12024 - 12842 bp
Length : 819 bp
Strand : -
Note : -

DNA sequence :
GTGCTCTGGCTTCGCGACCGCACCCTGGACCTCTCCCGCCCCCGGATCATGGGGATCCTCAACCTCACCCCCGATTCCTT
TTCCGATGGCGGCCTCTACCTGGACCCGGAAAGGGCCCTGGAAAGGGCCAAGACCCTGGTGGCCGAGGGCGCGGATCTTC
TGGACCTGGGGGCCGAATCCACCCGCCCCGGGGCCGAGCCCGTGTCCGTGGAGGAGGAAAAGAAGCGGCTTCTTCCCGCC
CTCGAGGCCATCCTGGAACTGGGGGTGCCGGTGAGCGTGGACACCCGCAAGCCCGAGGTGGCGGCGGAGGCCCTGAAGCT
GGGAGCGCACCTCATCAACGACGTGACGGGTCTTAGGGATGAGCGCATGGTGGCCCTCTGCGCCCGATATGGGGTGGCGG
CGGTGGTCATGCACATGCCCGTGCCCGACCCCCAGGCCATGATGGCCCACGCCCGCTACGGGAACGTGGTGGCCGAGGTG
AAGGCCTTCCTCAAGGCCCAGGCGGAAAGCGCCCTGAGGGCCGGGGTGCCCCAGGTGGTCCTGGACCCGGGGTTTGGCTT
CGGGAAACTTCTGGAACACAACCTGGCCCTCCTTAAACGCCTGGAAGAGATCGTGGCCCTGGGCCACCCCGTTTTGGTGG
GGCTTTCCCGGAAGCGCTCCATCGGGGAGCTCACGGGGGTGGAGGAACCGGCAAAAAGGGTCCTTGGCTCCGTGGCCGCC
CACCTTTTCGCCGCCATGAAGGGGGCCAGGATCCTTCGCGTCCACGACGTGGCCGCCCACCGGGAGGCCCTTGCGGTGTG
GAACGCCCTTTGGGAATAG

Protein sequence :
MLWLRDRTLDLSRPRIMGILNLTPDSFSDGGLYLDPERALERAKTLVAEGADLLDLGAESTRPGAEPVSVEEEKKRLLPA
LEAILELGVPVSVDTRKPEVAAEALKLGAHLINDVTGLRDERMVALCARYGVAAVVMHMPVPDPQAMMAHARYGNVVAEV
KAFLKAQAESALRAGVPQVVLDPGFGFGKLLEHNLALLKRLEEIVALGHPVLVGLSRKRSIGELTGVEEPAKRVLGSVAA
HLFAAMKGARILRVHDVAAHREALAVWNALWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sul2 AEZ06044.1 Sul2, sulphonamide-insensitive dihydropteroate synthase Not tested Tn6167 Protein 2e-26 41
sul2 AEA34678.1 dihydropteroate synthase Not tested Not named Protein 1e-26 41
sulI2 AFV47959.1 sulphonamide-insensitive dihydropteroate synthase SulI2 Not tested AbaR25 Protein 1e-26 41
BJAB0868_00253 YP_008211579.1 Dihydropteroate synthase-related enzyme Not tested AbaR26 Protein 2e-26 41
ABK1_0255 YP_005512827.1 Dihydropteroate synthase type-2 Not tested AbaR4d Protein 2e-26 41
BJAB07104_00246 YP_008207711.1 Dihydropteroate synthase-related enzyme Not tested AbaR25 Protein 2e-26 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
folP YP_004201215.1 dihydropteroate synthase NC_008702.1.4608834. Protein 2e-48 54
folP YP_004201215.1 dihydropteroate synthase NC_002516.2.881715.p Protein 4e-45 50
folP YP_004201215.1 dihydropteroate synthase CP001138.1.gene3456. Protein 3e-45 48
folP YP_004201215.1 dihydropteroate synthase CP002695.1.gene1085. Protein 1e-47 48
folP YP_004201215.1 dihydropteroate synthase NC_002695.1.916103.p Protein 1e-45 47
folP YP_004201215.1 dihydropteroate synthase CP004022.1.gene3451. Protein 2e-47 47
folP YP_004201215.1 dihydropteroate synthase CP000647.1.gene3624. Protein 1e-43 46
folP YP_004201215.1 dihydropteroate synthase CP000034.1.gene3358. Protein 2e-44 46
folP YP_004201215.1 dihydropteroate synthase AE000516.2.gene3902. Protein 1e-33 45
folP YP_004201215.1 dihydropteroate synthase NC_010410.6003232.p0 Protein 3e-37 45
folP YP_004201215.1 dihydropteroate synthase NC_011595.7059722.p0 Protein 3e-37 45
folP YP_004201215.1 dihydropteroate synthase NC_011586.7045137.p0 Protein 3e-37 45
folP YP_004201215.1 dihydropteroate synthase AM180355.1.gene1650. Protein 1e-42 44
folP YP_004201215.1 dihydropteroate synthase NC_003923.1002573.p0 Protein 5e-40 44
folP YP_004201215.1 dihydropteroate synthase NC_007622.3794340.p0 Protein 1e-38 44
folP YP_004201215.1 dihydropteroate synthase NC_002952.2860679.p0 Protein 4e-39 44
folP YP_004201215.1 dihydropteroate synthase NC_007793.3915320.p0 Protein 5e-40 44
folP YP_004201215.1 dihydropteroate synthase NC_010400.5986775.p0 Protein 5e-38 44
folP YP_004201215.1 dihydropteroate synthase AE016830.1.gene3181. Protein 2e-38 43
folP YP_004201215.1 dihydropteroate synthase NC_002951.3237126.p0 Protein 5e-39 43
folP YP_004201215.1 dihydropteroate synthase NC_002758.1120474.p0 Protein 2e-39 43
folP YP_004201215.1 dihydropteroate synthase NC_009782.5559617.p0 Protein 2e-39 43
folP YP_004201215.1 dihydropteroate synthase NC_002745.1123263.p0 Protein 2e-39 43
folP YP_004201215.1 dihydropteroate synthase NC_013450.8613224.p0 Protein 2e-39 43
folP YP_004201215.1 dihydropteroate synthase NC_009641.5330254.p0 Protein 2e-38 43
folP YP_004201215.1 dihydropteroate synthase DQ464881.1.gene2.p01 Protein 4e-26 41
folP YP_004201215.1 dihydropteroate synthase CP000675.2.gene3019. Protein 2e-45 41